Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Takahiro Iino"'
Autor:
Yumi Matsuyama, Tomoki Nakamura, Keisuke Yoshida, Tomohito Hagi, Takahiro Iino, Kunihiro Asanuma, Akihiro Sudo
Publikováno v:
Bone & Joint Research, Vol 11, Iss 10, Pp 715-722 (2022)
AimsAcridine orange (AO) demonstrates several biological activities. When exposed to low doses of X-ray radiation, AO increases the production of reactive radicals (radiodynamic therapy (AO-RDT)). We elucidated the efficacy of AO-RDT in breast and pr
Externí odkaz:
https://doaj.org/article/1c408b17f11747ba9c249229c5161f1b
Autor:
Yumi Matsuyama, Kunihiro Asanuma, Keisuke Yoshida, Tomohito Hagi, Takahiro Iino, Tomoki Nakamura, Akihiro Sudo
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-9 (2022)
Abstract Background Immune checkpoint protein (ICP), which is a central factor group of the immune system, has been reported to have a correlation between the degree of its expression and the prognosis of patients with malignant tumors, and many inhi
Externí odkaz:
https://doaj.org/article/ed14097b9bce4c6cb7d524c636f274c4
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2257 (2023)
Despite its widespread existence, there are relatively few drugs that can inhibit the progression of osteoarthritis (OA). Syndecan-4 (SDC4) is a transmembrane heparan sulfate proteoglycan that modulates cellular interactions with the extracellular ma
Externí odkaz:
https://doaj.org/article/7bdff567c9c34ecc998a831c6b85e94c
Publikováno v:
Communicative & Integrative Biology, Vol 15, Iss 1 (2022)
In reconstructive surgery using artificial materials after wide resection, soft tissues are usually adjacent to metal surfaces or mesh. The purpose of this study was to provide histological evaluation of the soft tissues adjacent to the metal surface
Externí odkaz:
https://doaj.org/article/34d1e758b8f1443b9a637a7ed8893d1b
Autor:
Koichi Nakamura, Kunihiro Asanuma, Takayuki Okamoto, Takahiro Iino, Tomohito Hagi, Tomoki Nakamura, Akihiro Sudo
Publikováno v:
Cancers, Vol 15, Iss 9, p 2468 (2023)
The combination of the mammalian target of rapamycin and proteasome inhibitors is a new treatment strategy for various tumors. Herein, we investigated the synergistic effect of everolimus and bortezomib on tumor growth and metastasis in bone and soft
Externí odkaz:
https://doaj.org/article/f5667cd0007f48529bc701640dfde2bf
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
BackgroundThe aims of this study were to analyze the effects of the administration of edaravone on C2C12 myoblasts exposed to oxidative stress; to evaluate the skeletal muscles in ob/ob mice; and to analyze the effect of the administration of edaravo
Externí odkaz:
https://doaj.org/article/e2a4c7b1223f4d7bb3eef4c46e28e241
Autor:
Sho Kato, Hiroki Wakabayashi, Taro Nakagawa, Gaku Miyamura, Yohei Naito, Takahiro Iino, Akihiro Sudo
Publikováno v:
Journal of Orthopaedic Surgery, Vol 28 (2019)
Purpose: The aim of this study was to examine the inhibitory effect of teriparatide (TPTD) on pain and on bone loss in ovariectomized (OVX) mice. The mechanism of osteoporotic pain in OVX mice was evaluated through an examination of pain-related beha
Externí odkaz:
https://doaj.org/article/2bb2013b6376443e8c350fef309a19ce
Publikováno v:
Journal of Orthopaedic Surgery, Vol 27 (2019)
Purpose: The purpose of this study was to evaluate local and systemic pathology in a murine model of ischemia–reperfusion (I/R) injury induced by long-term application of a tourniquet on the hind limbs and to assess the protective effects of edarav
Externí odkaz:
https://doaj.org/article/85ece16f8d0e404cb09d15b098433086
Publikováno v:
Journal of Orthopaedic Surgery, Vol 26 (2018)
Purpose: To determine the expression and distribution of bone morphogenetic protein (BMP)-7 and related molecules during peripheral nerve regeneration and to assess whether administration of parathyroid hormone (PTH) drug (1-34) potentiates the intri
Externí odkaz:
https://doaj.org/article/14d09b4452d14fb8aeb1590f6fed08a5
Autor:
Koichi Nakamura, Tomoki Nakamura, Takahiro Iino, Tomohito Hagi, Kouji Kita, Kunihiro Asanuma, Akihiro Sudo
Publikováno v:
Cancers, Vol 12, Iss 3, p 585 (2020)
Interleukin-6 (IL-6) affects the key parameters of oncogenesis, which increases the cell resistance to apoptosis, the proliferation of cancer cells, angiogenesis, invasion, malignancy, and the ability of tumor cells to respond to anticancer therapy.
Externí odkaz:
https://doaj.org/article/0c4ae20a95bc4338a2d84d850f10bbd0