Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Takahiro ITOYAMA"'
Autor:
Nobuyuki Kurosawa, Rika Fujimoto, Tatsuhiko Ozawa, Takahiro Itoyama, Naoki Sadamori, Masaharu Isobe
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55147 (2013)
BACKGROUND: Adult T-cell leukemia/lymphoma (ATLL) develops in a small proportion of human T-cell leukemia virus type I (HTLV-I)-infected individuals. However, the mechanism by which HTLV-I causes ATLL has not been fully elucidated. To provide fundame
Externí odkaz:
https://doaj.org/article/c07d257f8649478e8fcde50c2e88eeab
Publikováno v:
Kampo Medicine. 72:415-419
Autor:
Tatsuhiko Ozawa, Rika Fujimoto, Nobuyuki Kurosawa, Masaharu Isobe, Takahiro Itoyama, Naoki Sadamori
Publikováno v:
Cancer Genetics. 205:356-364
To provide fundamental insights into the leukemogenesis of adult T-cell leukemia/lymphoma (ATLL), we performed a molecular analysis of the chromosomal abnormalities in one ATLL case with a novel reciprocal translocation: t(2;14)(q34;q32). Using fluor
Autor:
Takahiro Itoyama, Masahito Tokunaga, Mayumi Tokunaga, Nobuhito Ohno, Minako Gotoh, Hirohito Tubouchi, Kouichi Haraguchi, Masafumi Taniwaki
Publikováno v:
Leukemia Research. 33:1552-1555
Most cases of acute promyelocytic leukemia (APL) are characterized by the reciprocal translocation t(15;17); however, several complex variant translocations have also been reported. Here we report complex cytogenetic abnormalities without t(15;17) as
Autor:
Hendrati Pirc-Danoewinata, Vadim G. Dyomin, Takahiro Itoyama, Gouri Nanjangud, R. S. K. Chaganti, Oskar A. Haas, Helmut Schmidt, Nallasivam Palanisamy
Publikováno v:
Oncogene. 23:6991-6996
The t(12;14)(q23;q32) breakpoints in a case of B-cell chronic lymphocytic leukemia (B-CLL) were mapped by fluorescence in situ hybridization (FISH) and Southern blot analysis and cloned using an IGH switch-gamma probe. The translocation affected a pr
Autor:
Weiyi Chen, Gouri Nanjungud, Takahiro Itoyama, Vadim G. Dyomin, R. S. K. Chaganti, Suresh C. Jhanwar, Julie Teruya-Feldstein, Andrew D. Zelenetz
Publikováno v:
Genes, Chromosomes and Cancer. 35:318-328
Abnormalities of chromosome arm 1q have frequently been reported in B-cell non-Hodgkin lymphoma (NHL), and correlated with poor outcome. Five genes mapped to this region (BCL9, MUC1, FCGR2B, IRTA1, and RTA2) have been shown to be deregulated by juxta
Autor:
Sunao Atogami, Masahiro Kikuchi, Takahiro Itoyama, Kunihiro Tsukasaki, Hideo Nakamura, Masao Tomonaga, Naoki Sadamori, R. S. K. Chaganti, Koichi Ohshima, Yasuaki Yamada
Publikováno v:
Blood. 97:3612-3620
Identification of cytogenetic abnormalities is an important clue for the elucidation of carcinogenesis. However, the cytogenetic and clinical significance of adult T-cell leukemia/lymphoma (ATLL) is still unclear. To address this point, cytogenetic f
Autor:
Kunihiro Tsukasaki, Masao Tomonaga, Takahiro Itoyama, Yasuaki Yamada, Shuichi Ikeda, Tomoko Hata, Fujimoto T, Hideo Nakamura, Naoki Sadamori
Publikováno v:
Cancer Genetics and Cytogenetics. 109:1-13
To detect chromosomal abnormalities in prodromal phase of adult T-cell leukemia (ATL), we established a clonal culture method for human T-lymphotropic virus type I (HTLV-I) infected T-cells in methylcellulose containing recombinant human interleukin
Publikováno v:
Leukemia Research. 22:793-796
We investigated parental origin of rearranged chromosomes 9 and 22 (9q+ and 22q−) in five patients with Ph-positive chronic myeloid leukemia (CML) using the C-banding and silver-staining methods of nucleolus organizer regions, respectively; of rear
Autor:
Yuji Ohno, Kenji Ishitsuka, Atae Utsunomiya, Yukiyoshi Moriuchi, Mototsugu Shimokawa, Yoshio Saburi, Nobuaki Nakano, Kunihiro Tsukasaki, Shuichi Hanada, Kiyoshi Yamashita, Takahiro Itoyama, Hiroo Katsuya, Eizaburo Sueoka, Naokuni Uike, Kazuo Tamura, Tetsuya Eto, Hitoshi Suzushima, Junji Suzumiya, Shinichiro Yoshida, Masaharu Miyahara
Publikováno v:
Blood. 128:4123-4123
Background: Adult T-cell leukemia-lymphoma (ATL), which is a hematological malignancy related to human T-lymphotropic virus type I (HTLV-1), is known as a malignant lymphoid disease with poor prognosis. Allogeneic hematopoietic stem cell transplantat