Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Takahiro Hanashi"'
Autor:
Koji Hori, Kimiko Konishi, Haijime Yuda, Atsuko Inamoto, Norihisa Akashi, Yuka Kitajima, Misa Hosoi, Takahiro Hanashi, Hiroi Tomioka, Hiromi Ouchi, Masayuki Tani, Mitsugu Hachisu, Kenzo Kurosawa
Publikováno v:
Neurodegenerative Diseases. 15:149-156
In this article, we review and repropose our hypothesis of the endogenous appearance of anticholinergic activity (AA) in Alzheimer's disease (AD). First, we introduce our previous articles and speculate that, because acetylcholine (ACh) regulates bot
Autor:
Kimiko Konishi, Nodoka Kikuchi, Takahiro Hanashi, Sayaka Hasegawa, Yuka Kitajima, Atsuko Inamoto, Hiroi Tomioka, Kenzo Kurosawa, Misa Hosoi, Masayuki Tani, Norihisa Akashi, Koji Hori, Takuji Izuno, Mitsugu Hachisu
Publikováno v:
Neuro-degenerative diseases. 15(3)
We report a case of a 54-year-old woman presenting with amnesia, apathy, work-related difficulties and mental stress. At presentation, her Mini-Mental State Examination score was 27 and her serum anticholinergic activity (SAA) was positive without me
Autor:
Kimiko Konishi, Yuka Kitajima, Hajime Yuda, Hiroi Tomioka, Hiromi Ouchi, Masayuki Tani, Misa Hosoi, Kenzo Kurosawa, Norihisa Akashi, Koji Hori, Atsuko Inamoto, Takahiro Hanashi, Mitsugu Hachisu
Publikováno v:
Neuro-degenerative diseases. 15(3)
We previously proposed the hypothesis of endogenous anticholinergic activity (AA) in Alzheimer's disease (AD). According to this hypothesis, the downregulation of acetylcholine seen in AD is associated with upregulation/hyperactivity of N-methyl-D-as