Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Takahiro Fuchigami"'
Autor:
Ikki Sakuma, Hidekazu Nagano, Naoko Hashimoto, Masanori Fujimoto, Akitoshi Nakayama, Takahiro Fuchigami, Yuki Taki, Tatsuma Matsuda, Hiroyuki Akamine, Satomi Kono, Takashi Kono, Masataka Yokoyama, Motoi Nishimura, Koutaro Yokote, Tatsuki Ogasawara, Yoichi Fujii, Seishi Ogawa, Eunyoung Lee, Takashi Miki, Tomoaki Tanaka
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Fructose-1,6-bisphosphatase (FBPase) deficiency, caused by an FBP1 mutation, is an autosomal recessive disorder characterized by hypoglycemic lactic acidosis. Due to the rarity of FBPase deficiency, the mechanism by which the mutations cause
Externí odkaz:
https://doaj.org/article/ec6b457d1727479d8857f01897a31d6d
Autor:
Kenny Anak Daun, Takahiro Fuchigami, Natsu Koyama, Noriko Maruta, Kazuhiro Ikenaka, Seiji Hitoshi
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Early life stress can exert detrimental or beneficial effects on neural development and postnatal behavior depending on the timing, duration, strength, and ability to control the stressors. In this study, we utilized a maternal and social deprivation
Externí odkaz:
https://doaj.org/article/1fccdc3e57a640cfb726a3035b0a3435
Publikováno v:
bioRxiv
The postnatal neural stem cell (NSC) pool hosts quiescent and activated radial glia-like NSCs contributing to neurogenesis throughout adulthood. However, the underlying regulatory mechanism during the transition from quiescent NSCs to activated NSCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d4a239b3d7ac24c060ba0f43ddc316
https://doi.org/10.1101/2023.03.14.532547
https://doi.org/10.1101/2023.03.14.532547
Publikováno v:
Mol Neurobiol
Parkinson’s disease (PD) is the second most common neurodegenerative disorder affecting the body and mind of millions of people in the world. As PD progresses, bradykinesia, rigidity, and tremor worsen. These motor symptoms are associated with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd09248a21504a0717516685aa9c406
https://europepmc.org/articles/PMC10140382/
https://europepmc.org/articles/PMC10140382/
Publikováno v:
Advances in Neurobiology ISBN: 9783031123894
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c4aa96c3d97981681e8b0e4d9fb15fb
https://doi.org/10.1007/978-3-031-12390-0_14
https://doi.org/10.1007/978-3-031-12390-0_14
Publikováno v:
Advances in neurobiology. 29
Patients with nervous system disorders suffer from impaired cognitive, sensory and motor functions that greatly inconvenience their daily life and usually burdens their family and society. It is difficult to achieve functional recovery for the damage
Autor:
Aoi Tanaka, Takahiro Fuchigami, Seiji Hitoshi, Shohei Ishida, Anri Kuroda, Yoshitaka Hayashi, Yugo Fukazawa, Kazuhiro Ikenaka
Publikováno v:
Cerebral cortex (New York, N.Y. : 1991). 30(12):6415-6425
The origin and life-long fate of quiescent neural stem cells (NSCs) in the adult mammalian brain remain largely unknown. A few neural precursor cells in the embryonic brain elongate their cell cycle time and subsequently become quiescent postnatally,
Publikováno v:
Mol Ther
Parkinson's disease (PD) is characterized by Lewy bodies (composed predominantly of alpha-synuclein [aSyn]) and loss of pigmented midbrain dopaminergic neurons comprising the nigrostriatal pathway. Most PD patients show significant deficiency of gang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3c35c90eacbb8ae16a875030b4cc5b
https://europepmc.org/articles/PMC8531229/
https://europepmc.org/articles/PMC8531229/
Publikováno v:
Neurochemical Research. 43:219-226
Minocycline not only has antibacterial action but also produces a variety of pharmacological effects. It has drawn considerable attention as a therapeutic agent for symptoms caused by inflammation in many neurological disorders, leading to several cl
Autor:
Shin-ichi Hisanaga, Mitsuharu Hattori, Ken Ichiro Kubo, Taro Saito, Kazunori Nakajima, Mitsunori Fukuda, Takahiro Fuchigami, Yukinori Tsuchiya, Shin Ya Miyauchi, Tetsuya Takano, Yuya Tomita, Yutaka Sato
Publikováno v:
Genes to Cells. 18:410-424
Reelin-Dab1 signaling is indispensable for proper positioning of neurons in mammalian brain. Reelin is a glycoprotein secreted from Cajal-Reztuis cells in marginal zone of cerebral cortex, and its receptors are Apolipoprotein E receptor 2 (ApoER2) or