Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Takahiro, TSUJIMURA"'
Autor:
Takayuki Morimoto, Tsutomu Nakazawa, Ryosuke Maeoka, Ryosuke Matsuda, Mitsutoshi Nakamura, Fumihiko Nishimura, Shuichi Yamada, Ichiro Nakagawa, Young-Soo Park, Takahiro Tsujimura
Publikováno v:
Regenerative Therapy, Vol 25, Iss , Pp 367-376 (2024)
Introduction: Innate immune cells are important in tumor immunotherapy. Natural killer cells (NKCs) are also categorized as innate immune cells and can control tumor growth and metastatic spread. Glioblastoma (GBM) is the most common and aggressive p
Externí odkaz:
https://doaj.org/article/be4643f40ac640d0ada6eb83d5f6e08a
Autor:
Tsutomu Nakazawa, Ryosuke Maeoka, Takayuki Morimoto, Ryosuke Matsuda, Mitsutoshi Nakamura, Fumihiko Nishimura, Shuichi Yamada, Ichiro Nakagawa, Young-Soo Park, Toshihiro Ito, Hiroyuki Nakase, Takahiro Tsujimura
Publikováno v:
Regenerative Therapy, Vol 24, Iss , Pp 32-42 (2023)
Introduction: Natural killer cells (NKCs) are immune cells that can attack cancer cells through the direct recognition of ligands without prior sensitization. Cord blood-derived NKCs (CBNKCs) represent a promising tool for allogenic NKC-based cancer
Externí odkaz:
https://doaj.org/article/99ed7a75bb9e402cb9fb37eedbaf9b59
Autor:
Tsutomu Nakazawa, Takayuki Morimoto, Ryosuke Maeoka, Ryosuke Matsuda, Mitsutoshi Nakamura, Fumihiko Nishimura, Noriko Ouji, Shuichi Yamada, Ichiro Nakagawa, Young Soo Park, Toshihiro Ito, Hiroyuki Nakase, Takahiro Tsujimura
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-22 (2023)
Abstract Background Glioblastoma (GBM) is the most common malignant brain tumor and has “immunologically cold” features. Changing GBM to an “immunologically hot” tumor requires a strong trigger that induces initial immune responses in GBM. Al
Externí odkaz:
https://doaj.org/article/dab32889ea614f1b8035bdd96dbc57d7
Autor:
Tsutomu Nakazawa, Takayuki Morimoto, Ryosuke Maeoka, Kengo Yamada, Ryosuke Matsuda, Mitsutoshi Nakamura, Fumihiko Nishimura, Shuichi Yamada, Young-Soo Park, Takahiro Tsujimura, Ichiro Nakagawa
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5896 (2024)
Enhancing immune cell functions in tumors remains a major challenge in cancer immunotherapy. Natural killer cells (NK) are major innate effector cells with broad cytotoxicity against tumors. Accordingly, NK cells are ideal candidates for cancer immun
Externí odkaz:
https://doaj.org/article/f7a3a2b06fb0432db9c103e713a3cd3d
Autor:
Tsutomu Nakazawa, Takayuki Morimoto, Ryosuke Maeoka, Ryosuke Matsuda, Mitsutoshi Nakamura, Fumihiko Nishimura, Shuichi Yamada, Ichiro Nakagawa, Young-Soo Park, Hiroyuki Nakase, Takahiro Tsujimura
Publikováno v:
Regenerative Therapy, Vol 21, Iss , Pp 185-191 (2022)
Introduction: Cell-based immunotherapy is categorized as a regenerative therapy under the Regenerative Medicine Safety Act in Japan. Natural killer (NK) cell-based immunotherapy is considered a promising strategy for treating cancer, including gliobl
Externí odkaz:
https://doaj.org/article/987a5b807c6e42b8837923fa9a3d6a82
Autor:
Takayuki Morimoto, Tsutomu Nakazawa, Ryosuke Matsuda, Ryosuke Maeoka, Fumihiko Nishimura, Mitsutoshi Nakamura, Shuichi Yamada, Young-Soo Park, Takahiro Tsujimura, Ichiro Nakagawa
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2435 (2024)
Despite standard multimodality treatment, containing maximum safety resection, temozolomide, radiotherapy, and a tumor-treating field, patients with glioblastoma (GBM) present with a dismal prognosis. Natural killer cell (NKC)-based immunotherapy wou
Externí odkaz:
https://doaj.org/article/e69d7435536e4836bf434d53e72855bc
Autor:
Ryosuke Maeoka, Tsutomu Nakazawa, Ryosuke Matsuda, Takayuki Morimoto, Yoichi Shida, Shuichi Yamada, Fumihiko Nishimura, Mitsutoshi Nakamura, Ichiro Nakagawa, Young-Soo Park, Takahiro Tsujimura, Hiroyuki Nakase
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14183 (2023)
Glioblastoma (GBM) is the leading malignant intracranial tumor, where prognosis for which has remained extremely poor for two decades. Immunotherapy has recently drawn attention as a cancer treatment, including for GBM. Natural killer (NK) cells are
Externí odkaz:
https://doaj.org/article/98f914e467f249148763ec6520dbc1b3
Autor:
Takayuki Morimoto, Tsutomu Nakazawa, Ryosuke Maeoka, Ichiro Nakagawa, Takahiro Tsujimura, Ryosuke Matsuda
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2111 (2023)
Glioblastoma (GBM) is the most aggressive and malignant primary brain tumor in adults. Despite multimodality treatment involving surgical resection, radiation therapy, chemotherapy, and tumor-treating fields, the median overall survival (OS) after di
Externí odkaz:
https://doaj.org/article/26380806298e49b3bbdfd55d3716d2b6
Autor:
Tsutomu Nakazawa, Ryosuke Maeoka, Takayuki Morimoto, Ryosuke Matsuda, Mitsutoshi Nakamura, Fumihiko Nishimura, Shuichi Yamada, Ichiro Nakagawa, Young-Soo Park, Hiroyuki Nakase, Takahiro Tsujimura
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12992 (2022)
Irradiated murine induced-pluripotent stem cells (iPSCs) elicit the antitumor response in vivo. However, it is unclear whether human iPSCs would elicit antitumor effects. In the present study, we investigated the capability of human iPSC lysate (iPSL
Externí odkaz:
https://doaj.org/article/499e801e68b642c2bbaaf391a1fdac6f
Autor:
Yoichi Shida, Tsutomu Nakazawa, Ryosuke Matsuda, Takayuki Morimoto, Fumihiko Nishimura, Mitsutoshi Nakamura, Ryosuke Maeoka, Shuichi Yamada, Ichiro Nakagawa, Young-Soo Park, Motoaki Yasukawa, Takashi Tojo, Takahiro Tsujimura, Hiroyuki Nakase
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9975 (2021)
Glioblastoma (GBM) is the leading malignant intracranial tumor and is associated with a poor prognosis. Highly purified, activated natural killer (NK) cells, designated as genuine induced NK cells (GiNKs), represent a promising immunotherapy for GBM.
Externí odkaz:
https://doaj.org/article/f9f06084ec364a94832d1c8cfbf323d6