Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Takahiro, Nagatake"'
Autor:
Koji Hosomi, Noritoshi Hatanaka, Atsushi Hinenoya, Jun Adachi, Yoko Tojima, Mari Furuta, Keita Uchiyama, Makiko Morita, Takahiro Nagatake, Azusa Saika, Soichiro Kawai, Ken Yoshii, Saki Kondo, Shinji Yamasaki, Jun Kunisawa
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionCampylobacter spp. are a public health concern, yet there is still no effective vaccine or medicine available.MethodsHere, we developed a Campylobacter jejuni-specific antibody and found that it targeted a menaquinol cytochrome c reductas
Externí odkaz:
https://doaj.org/article/377cf10cccfd4ba19f78854bf5fa0d34
Autor:
Azusa Saika, Takahiro Nagatake, Shigenobu Kishino, Nahoko Kitamura, Tetsuya Honda, Koji Hosomi, Prabha Tiwari, Eri Node, Soichiro Kawai, Saki Kondo, Kei Ishida, Kenji Kabashima, Jun Ogawa, Jun Kunisawa
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Intestinal bacteria metabolize dietary substances to produce bioactive postbiotics, among which some are recognized for their role in promoting host health. We here explored the postbiotic potential of two omega-3 α-linolenic acid–derived metaboli
Externí odkaz:
https://doaj.org/article/022a996b610841cea714f99a2292266c
Autor:
Shota Kajiyama, Takahiro Nagatake, Satoru Ishikawa, Koji Hosomi, Yuki Shimada, Yasunori Matsui, Jun Kunisawa
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Immune cell activation is essential for cancer rejection; however, the tumor microenvironment leads to deterioration of immune function, which enables cancer cells to survive and proliferate. We previously reported that oral ingestion of Len
Externí odkaz:
https://doaj.org/article/4953b808495f4145be84f1af1eb460b6
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Iodine-containing formulations have been widely used to treat iodine deficiency and as antiseptics. Lecithin-bound iodine (LBI) has been approved to treat allergic diseases in Japan; however, its underlying mechanism remains unknown. In this
Externí odkaz:
https://doaj.org/article/75cad2e71dff494dbe216b44cb6a3716
Autor:
Koji Hosomi, Mayu Saito, Jonguk Park, Haruka Murakami, Naoko Shibata, Masahiro Ando, Takahiro Nagatake, Kana Konishi, Harumi Ohno, Kumpei Tanisawa, Attayeb Mohsen, Yi-An Chen, Hitoshi Kawashima, Yayoi Natsume-Kitatani, Yoshimasa Oka, Hidenori Shimizu, Mari Furuta, Yoko Tojima, Kento Sawane, Azusa Saika, Saki Kondo, Yasunori Yonejima, Haruko Takeyama, Akira Matsutani, Kenji Mizuguchi, Motohiko Miyachi, Jun Kunisawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Here, the authors inversely associate Blautia wexlerae with obesity and type 2 diabetes mellitus in humans and further show that administration of B. wexlerae to mice decrease both high-fat diet–induced obesity and diabetes via modulating gut micro
Externí odkaz:
https://doaj.org/article/17725b6c6ae24b218512afb8a846b033
Autor:
Kei Ishida, Takahiro Nagatake, Azusa Saika, Soichiro Kawai, Eri Node, Koji Hosomi, Jun Kunisawa
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Macrophages manifest as various subtypes that play diverse and important roles in immunosurveillance and the maintenance of immunological homeostasis in various tissues. Many in vitro studies divide macrophages into two broad groups: M1 macrophages i
Externí odkaz:
https://doaj.org/article/d2c8bd5da58d43838fde5573d46cddac
Autor:
Azusa Saika, Prabha Tiwari, Takahiro Nagatake, Eri Node, Koji Hosomi, Tetsuya Honda, Kenji Kabashima, Jun Kunisawa
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Retinol is widely used in topical skincare products to ameliorate skin aging and treat acne and wrinkles; however, retinol and its derivatives occasionally have adverse side effects, including the induction of irritant contact dermatitis. Previously,
Externí odkaz:
https://doaj.org/article/d7afa3a0165a44cea3a15e458946c45b
Autor:
Takahiro Nagatake, Yuki Shibata, Sakiko Morimoto, Eri Node, Kento Sawane, So-ichiro Hirata, Jun Adachi, Yuichi Abe, Junko Isoyama, Azusa Saika, Koji Hosomi, Takeshi Tomonaga, Jun Kunisawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Atherosclerosis is a chronic inflammatory disease associated with macrophage aggregate and transformation into foam cells. In this study, we sought to investigate the impact of dietary intake of ω3 fatty acid on the development of atheroscl
Externí odkaz:
https://doaj.org/article/46db4e714e7349749bbe4ce5c4ec444c
Publikováno v:
FEBS Open Bio, Vol 10, Iss 1, Pp 28-40 (2020)
The functional state (FS) of adult pancreatic islets is regulated by a large array of regulatory molecules including numerous transcription factors. Whether any islet structural molecules play such a role has not been well understood. Here, multiple
Externí odkaz:
https://doaj.org/article/37eb1df581bd45cfb92a11e63c42ebca
Autor:
Azusa Saika, Takahiro Nagatake, Shigenobu Kishino, Si‐Bum Park, Tetsuya Honda, Naomi Matsumoto, Michiko Shimojou, Sakiko Morimoto, Prabha Tiwari, Eri Node, So‐ichiro Hirata, Koji Hosomi, Kenji Kabashima, Jun Ogawa, Jun Kunisawa
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 1, Pp 59-71 (2020)
Abstract Dietary intake of ω3 polyunsaturated fatty acids such as eicosapentaenoic acid and docosahexaenoic acid is beneficial for health control. We recently identified 17,18‐epoxyeicosatetraenoic acid (17,18‐EpETE) as a lipid metabolite endoge
Externí odkaz:
https://doaj.org/article/4e11a89c773a4e4daef81db04045be1d