Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Takahiko Utsugi"'
Autor:
Masaki Umezawa, Masaya Ohtsu, Mayumi Waki, Dai Kato, Yuka Aoki, Takahiko Utsugi, Yasufumi Murakami
Publikováno v:
Biochemical and Biophysical Research Communications. 417:433-438
Double strand breaks (DSBs) are the most serious type of DNA damage. DSBs can be generated directly by exposure to ionizing radiation or indirectly by replication fork collapse. The DNA damage tolerance pathway, which is conserved from bacteria to hu
Publikováno v:
Genes to Cells. 16:166-178
Many of the genes that control cyclin-dependent kinase (Cdks) activity have been identified by genetic research using yeast mutants. Suppression analysis and synthetic enhancement analysis are two broad approaches to the identification of genetic int
Autor:
Mika Kawate, Fumio Hanaoka, Wataru Gunji, Masashi Fukuoka, Yasufumi Murakami, Fumitoshi Onoda, Masaya Ohtsu, Takahiko Utsugi
Publikováno v:
DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
Transcriptional activation and repression are a key step in the regulation of all cellular activities. The development of comprehensive analysis methods such as DNA microarray has advanced our understanding of the correlation between the regulation o
Publikováno v:
Biochemical and Biophysical Research Communications. 365(3):472-477
Temperature-sensitive (ts) mutants are powerful tools with which to investigate gene function, but it has been difficult to generate ts mutants in mammalian cells. Recently, RNA interference (RNAi) has been widely used for loss of function analyses.
Publikováno v:
Mycotoxins. 55:117-128
The DNA microarray technology is a very useful tool for a comprehensive analysis of the gene expression profile. On the other hand, cost, sensitivity, accuracy, and reproducibility are some of the many problems that must still be solved for this tech
Autor:
Mitsuhiro Abe, Takahiko Utsugi, Daisuke Watanabe, Yoshikazu Ohya, Aiko Hirata, Masayo Minemura
Publikováno v:
Genes to Cells. 7:1-9
Background : The cell wall has an important role in maintaining cell shape. In the budding yeast Saccharomyces cerevisiae , the major filamentous component of the cell wall responsible for its rigidity is 1,3- β glucan and is synthesized by 1,3- β
Autor:
Steven A. Edling, Yoshiko Kikuchi, William Gump, Takeshi Sasaki, Takahiko Utsugi, Steven R. Ellis, Clavia R. Wooten-Kee, Amy L. Tabb
Publikováno v:
Genetics. 157:1107-1116
The Saccharomyces cerevisiae RPS0A/B genes encode proteins of the 40S ribosomal subunit that are required for the maturation of 18S rRNA. We show here that the RPS0 genes interact genetically with TOM1. TOM1 encodes a member of the hect-domain-contai
Publikováno v:
Gene. 234:285-295
A tom1-1 mutant was isolated from Saccharomyces cerevisiae. At high temperatures, 60% of the cells were arrested as dumbbell forms with a single large nucleus containing duplicated DNA and a short spindle. Electron-microscopy showed electron-dense st
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1263:285-288
A new gene ( STM1 ;_suppressor of_to_ml) Saccharomyces cerevisiae was isolated by the ability to suppress the temperature sensitivity of a tom1 mutant, by increasing its gene dosage. The gene could also suppress the temperature sensitivity of the htr
Autor:
Makoto, Inaki, Dai, Kato, Takahiko, Utsugi, Fumitoshi, Onoda, Fumio, Hanaoka, Yasufumi, Murakami
Publikováno v:
Genes to cells : devoted to molecularcellular mechanisms. 16(2)
Many of the genes that control cyclin-dependent kinase (Cdks) activity have been identified by genetic research using yeast mutants. Suppression analysis and synthetic enhancement analysis are two broad approaches to the identification of genetic int