Zobrazeno 1 - 10
of 236
pro vyhledávání: '"Takahiko Nakagawa"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Bone marrow-derived cells (BMDCs) are heterogeneous populations in which not only pluripotent stem cells, namely, hematopoietic stem cells (HSCs), mesenchymal stem cells (MSC) but also endothelial progenitor cells (EPC) are involved. BMDCs contribute
Externí odkaz:
https://doaj.org/article/243b69cded544e799cad6890b1d6735f
Autor:
Hideto Kojima, Miwako Katagi, Junko Okano, Yuki Nakae, Natsuko Ohashi, Kazunori Fujino, Itsuko Miyazawa, Takahiko Nakagawa
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Despite the growing epidemic worldwide, diabetes is an incurable disease. We have been focusing on why diabetes manifests refractoriness to any therapy. We recently found that abnormal bone marrow-derived cells (BMDCs), namely, Vcam-1+ST-HSC
Externí odkaz:
https://doaj.org/article/23671901db2d4547b23779f640d86201
Autor:
Yuuki Shirai, Junko Okano, Takahiko Nakagawa, Miwako Katagi, Yuki Nakae, Atsuhiro Arakawa, Shinya Koshinuma, Gaku Yamamoto, Hideto Kojima
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Deep skin wounds with periosteal defects, frequently caused by traffic accidents or radical dissection, are refractory. Transplant surgery is frequently performed, but patients are subjected to stress for long operation periods, the sacrific
Externí odkaz:
https://doaj.org/article/38647d5ca48a4c0998eb0a0c92f32d44
Autor:
Takahiko Nakagawa, Duk-Hee Kang
Publikováno v:
Kidney Research and Clinical Practice, Vol 40, Iss 4, Pp 527-541 (2021)
The Warburg effect is a unique property of cancer cells, in which glycolysis is activated instead of mitochondrial respiration despite oxygen availability. However, recent studies found that the Warburg effect also mediates non-cancer disorders, incl
Externí odkaz:
https://doaj.org/article/4a255fd4e8944ccaa3cb2d34103951cd
Autor:
Mehdi A. Fini, Miguel A. Lanaspa, Eric A. Gaucher, Brian Boutwell, Takahiko Nakagawa, Richard M. Wright, Laura G. Sanchez-Lozada, Peter Andrews, Kurt R. Stenmark, Richard J. Johnson
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-5 (2021)
Abstract Background Recent studies suggest that fructose, as well as its metabolite, uric acid, have been associated with increased risk for both cancer incidence and growth. Both substances are known to cause oxidative stress to mitochondria and to
Externí odkaz:
https://doaj.org/article/6cf8865c41f7429f8e6c8c278ac69c75
Publikováno v:
BMJ Open, Vol 12, Iss 8 (2022)
Objectives Haemoglobin concentration is a potentially modifiable factor that may help lower the risk of intradialytic hypotension (IDH), but its association with IDH is not well understood. This study aimed to clarify the relationship between haemogl
Externí odkaz:
https://doaj.org/article/87250009753c450d9277c44ed61ee864
Autor:
Miwako Katagi, Tomoya Terashima, Natsuko Ohashi, Yuki Nakae, Akane Yamada, Takahiko Nakagawa, Itsuko Miyazawa, Hiroshi Maegawa, Junko Okano, Yoshihisa Suzuki, Kazunori Fujino, Yutaka Eguchi, Hideto Kojima
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Katagi et al. show that abnormal bone marrow-derived cells originated from hematopoietic stem cells (CD106-positive short-term HSCs) aberrantly fuse with neurons to develop diabetic neuropathy. This study suggests that the pathological abnormality is
Externí odkaz:
https://doaj.org/article/e89bf4e21fc54a66a503dcaba1d6baae
Autor:
Junko Okano, Yuki Nakae, Takahiko Nakagawa, Miwako Katagi, Tomoya Terashima, Daisuke Nagakubo, Takashi Nakayama, Osamu Yoshie, Yoshihisa Suzuki, Hideto Kojima
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Exposure to moderate doses of ionizing radiation (IR), which is sufficient for causing skin injury, can occur during radiation therapy as well as in radiation accidents. Radiation-induced skin injury occasionally recovers, although its under
Externí odkaz:
https://doaj.org/article/6af682acd4a34395939e1f2e7783ce9b
Autor:
Ana Andres-Hernando, David J. Orlicky, Christina Cicerchi, Masanari Kuwabara, Gabriela E. Garcia, Takahiko Nakagawa, Laura Gabriela Sanchez-Lozada, Richard J. Johnson, Miguel A. Lanaspa
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 780 (2023)
The presence of obesity and metabolic syndrome is strongly linked with chronic kidney disease (CKD), but the mechanisms responsible for the association are poorly understood. Here, we tested the hypothesis that mice with obesity and metabolic syndrom
Externí odkaz:
https://doaj.org/article/3ec6a4967d224e0ca7fbc7778e645436
Autor:
Takahiko Nakagawa, Miguel A. Lanaspa, Inigo San Millan, Mehdi Fini, Christopher J. Rivard, Laura G. Sanchez-Lozada, Ana Andres-Hernando, Dean R. Tolan, Richard J. Johnson
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-12 (2020)
Abstract Obesity and metabolic syndrome are strongly associated with cancer, and these disorders may share a common mechanism. Recently, fructose has emerged as a driving force to develop obesity and metabolic syndrome. Thus, we assume that fructose
Externí odkaz:
https://doaj.org/article/28f0bb6a5bc74d3795be8b5f9ba50730