Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Takahiko Usui"'
Autor:
Tomohiko Urano, Masayo Fujita, Takahiko Usui, Kotaro Azuma, Satoshi Inoue, Nobuhiro Ijichi, Kuniko Horie-Inoue, Yasuyoshi Ouchi, Kazuhiro Ikeda
Publikováno v:
The Open Bone Journal. 1:28-37
Glucocorticoid-induced osteoporosis is a clinical problem in patients under chronic steroid therapy. To delineate the action of glucocorticoids on osteoblasts, we performed microarray analysis using rat primary osteoblasts and identified several gluc
Publikováno v:
Geriatrics & Gerontology International. 9:235-241
Background: Nuclear receptors play an important role in bone metabolism. In bone cells, the vitamin D receptor (VDR) and the steroid and xenobiotic receptor (SXR) are activated by vitamin D and vitamin K2, respectively. VDR and SXR are the NR1I subfa
Autor:
Masataka Shiraki, Satoshi Inoue, Takahiko Usui, Yasuyoshi Ouchi, Noriko Sasaki, Tomohiko Urano
Publikováno v:
Endocrine Journal. 56:625-631
Wnt signaling is an important regulator of bone homeostasis. The Wnt co-receptor, namely, low-density lipoprotein receptor-related protein 5 (LRP5), initiates Wnt signal transduction. Recently, we and several other groups have shown that there is a s
Autor:
Noriko Sasaki, Yasuyoshi Ouchi, Satoshi Inoue, Takahiko Usui, Tomohiko Urano, Kenichiro Narusawa, Takayuki Hosoi, Toshitaka Nakamura, Masataka Shiraki
Publikováno v:
Spine. 33:1256-1261
Study design An association study investigating the genetic etiology for spinal disc degeneration. Objective To determine the association of single-nucleotide polymorphism (SNP) in the insulin-like growth factor-1 receptor (IGF1R) with spinal disc de
Publikováno v:
Geriatrics & Gerontology International. 7:48-53
Background: Wnt signaling pathway regulates bone mineral density (BMD) through the lipoprotein receptor-related protein (LRP)5, a receptor of this signaling. Recently, we and several groups have shown that genetic variations at the LRP5 gene locus ar
Autor:
Noriko Sasaki, Yasuyoshi Ouchi, Tomohiko Urano, Masataka Shiraki, Takahiko Usui, Satoshi Inoue, Takayuki Hosoi, Toshitaka Nakamura, Kenʼichiro Narusawa
Publikováno v:
Spine. 32:25-29
STUDY DESIGN An association study investigating the genetic etiology for spinal osteoarthritis. OBJECTIVE To determine the association of single-nucleotide polymorphism (SNP) causing an amino-acid change (Q89R) in the low-density lipoprotein receptor
Autor:
Satoshi Inoue, Takahiko Usui, Yasuyoshi Ouchi, Noriko Sasaki, Tomohiko Urano, Masataka Shiraki
Publikováno v:
Bone. 47(3)
Genetic factors are important for the development of osteoporosis. During the search for novel markers of single-nucleotide polymorphisms (SNPs) associated with bone mineral density (BMD) by performing a large-scale SNP screen with 251 Japanese postm
Publikováno v:
Journal of aquatic animal health. 20(4)
The epidemic process of the parasite Ichthyophonus hoferi in cultured rainbow trout Oncorhynchus mykiss was quantitatively estimated by both the cohabitation experiment and two standard models (the Kermarck-McKendrick model and the Reed-Frost model).
Autor:
Kazuhiro Ikeda, Takahiko Usui, Jun Otomo, Shizu Takeda, Satoshi Inoue, Takao Iwayanagi, Yasuyoshi Ouchi, Tomohiko Urano, Atsushi Okada, Yoshiko Ishida
Publikováno v:
Biochemical and biophysical research communications. 383(2)
Terf/TRIM17 is a member of the TRIM family of proteins, which is characterized by the RING finger, B-box, and coiled-coil domains. In the present study, we found that terf interacts with TRIM44. Terf underwent ubiquitination in vitro in the presence
Autor:
Takahiko Usui, Satoshi Inoue, Takayuki Hosoi, Yasuyoshi Ouchi, Toshitaka Nakamura, Masataka Shiraki, Tomohiko Urano, Kenichiro Narusawa, Noriko Sasaki
Publikováno v:
Journal of bone and mineral metabolism. 25(4)
The Wnt-beta-catenin signaling pathway that regulates bone density is also involved in cartilage development and homeostasis in vivo. Here, we assumed that genetic variation in Wnt-beta-catenin signaling genes can affect the pathogenesis of cartilage