Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Takahiko , Murayama"'
Autor:
Mitsuhito Hirano, Yoichi Imai, Yuta Kaito, Takahiko Murayama, Kota Sato, Tadao Ishida, Junichi Yamamoto, Takumi Ito, Muneyoshi Futami, Masaki Ri, Hiroshi Yasui, Tamami Denda, Yukihisa Tanaka, Yasunori Ota, Masanori Nojima, Yasuhiko Kamikubo, Noriko Gotoh, Shinsuke Iida, Hiroshi Handa, Arinobu Tojo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Abstract Background Multiple myeloma (MM) is an incurable disease. The acquisition of resistance to drugs, including immunomodulatory drugs (IMiDs), has a negative effect on its prognosis. Cereblon (CRBN) is a key mediator of the bioactivities of IMi
Externí odkaz:
https://doaj.org/article/f2e71599d7d641fb9ece99c28c22cc0d
Autor:
David A. Barbie, Matthew G. Oser, Ellis L. Reinherz, Scott Rodig, Robin Edwards, Evisa Gjini, Pasi A. Jänne, Kathleen Pfaff, Michael Y. Tolstorukov, Lynette M. Sholl, Fangxin Hong, Benjamin Chen, Xi-Tao Wang, Ana Lako, Eliezer M. Van Allen, Mark M. Awad, Cloud P. Paweletz, Prafulla C. Gokhale, Brendan Reardon, Hideo Watanabe, Maya Fridrikh, Aoi Akitsu, Shunsuke Kitajima, Israel Cañadas, Takahiko Murayama, Alison D. Santucci, Victor Quadros, Andrew Portell, Patrick H. Lizotte, Luke J. Taus, Michael J. Poitras, Jonathan S. Duke-Cohan, Bruce B. Reinhold, Saemi Han, Brandon Piel, Tran C. Thai, Deli Hong, Marco Campisi, Maria Saigí, Amir Vajdi, Jacquelyn O. Wolff, Erik H. Knelson, Navin R. Mahadevan
Small cell lung carcinoma (SCLC) is highly mutated, yet durable response to immune checkpoint blockade (ICB) is rare. SCLC also exhibits cellular plasticity, which could influence its immunobiology. Here we discover that a distinct subset of SCLC uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4647caa0d1c61ca9a140b00973df6824
https://doi.org/10.1158/2159-8290.c.6549244.v1
https://doi.org/10.1158/2159-8290.c.6549244.v1
Autor:
David A. Barbie, Matthew G. Oser, Ellis L. Reinherz, Scott Rodig, Robin Edwards, Evisa Gjini, Pasi A. Jänne, Kathleen Pfaff, Michael Y. Tolstorukov, Lynette M. Sholl, Fangxin Hong, Benjamin Chen, Xi-Tao Wang, Ana Lako, Eliezer M. Van Allen, Mark M. Awad, Cloud P. Paweletz, Prafulla C. Gokhale, Brendan Reardon, Hideo Watanabe, Maya Fridrikh, Aoi Akitsu, Shunsuke Kitajima, Israel Cañadas, Takahiko Murayama, Alison D. Santucci, Victor Quadros, Andrew Portell, Patrick H. Lizotte, Luke J. Taus, Michael J. Poitras, Jonathan S. Duke-Cohan, Bruce B. Reinhold, Saemi Han, Brandon Piel, Tran C. Thai, Deli Hong, Marco Campisi, Maria Saigí, Amir Vajdi, Jacquelyn O. Wolff, Erik H. Knelson, Navin R. Mahadevan
Supplementary Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdb01871ac4703e7fdf6229583a3de7
https://doi.org/10.1158/2159-8290.22540003.v1
https://doi.org/10.1158/2159-8290.22540003.v1
Autor:
David A. Barbie, Matthew G. Oser, Ellis L. Reinherz, Scott Rodig, Robin Edwards, Evisa Gjini, Pasi A. Jänne, Kathleen Pfaff, Michael Y. Tolstorukov, Lynette M. Sholl, Fangxin Hong, Benjamin Chen, Xi-Tao Wang, Ana Lako, Eliezer M. Van Allen, Mark M. Awad, Cloud P. Paweletz, Prafulla C. Gokhale, Brendan Reardon, Hideo Watanabe, Maya Fridrikh, Aoi Akitsu, Shunsuke Kitajima, Israel Cañadas, Takahiko Murayama, Alison D. Santucci, Victor Quadros, Andrew Portell, Patrick H. Lizotte, Luke J. Taus, Michael J. Poitras, Jonathan S. Duke-Cohan, Bruce B. Reinhold, Saemi Han, Brandon Piel, Tran C. Thai, Deli Hong, Marco Campisi, Maria Saigí, Amir Vajdi, Jacquelyn O. Wolff, Erik H. Knelson, Navin R. Mahadevan
Supplementary Figures 1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219fb0a74b9ede1ef293c6a7f98f274e
https://doi.org/10.1158/2159-8290.22540006.v1
https://doi.org/10.1158/2159-8290.22540006.v1
Publikováno v:
International Journal of Geosciences. 13:1103-1114
Autor:
Takahiko Murayama, Noriko Gotoh
Publikováno v:
Cells, Vol 8, Iss 6, p 621 (2019)
Recently, patient-derived xenograft (PDX) models of many types of tumors including breast cancer have emerged as a powerful tool for predicting drug efficacy and for understanding tumor characteristics. PDXs are established by the direct transfer of
Externí odkaz:
https://doaj.org/article/9ec183554fdd4d509998589f2f6f737b
Autor:
Takahiko Murayama, Navin R. Mahadevan, Tetsuo Tani, Xueying Ma, Hideo Watanabe, David A. Barbie, Israel Cañadas
Publikováno v:
Cancer Research. 83:5145-5145
Small cell lung cancer (SCLC) is the most lethal type of lung cancer. The uniqueness of this tumor consists of an initial exquisite response to chemotherapy. However, at relapse, which occurs nearly in all patients, the tumor is resistant to all avai
Autor:
Toyoaki Natsume, Satoshi Inoue, Noriko Gotoh, Asako Sasahara, Masahiko Tanabe, Takayuki Enomoto, Rojas-Chaverra N. Marcela, Tatsunori Nishimura, Kuniko Horie-Inoue, Kana Tominaga, Masato T. Kanemaki, Kei-Ichiro Tada, Koji Okamoto, Satoko Ishikawa, Mengjiao Li, Arinobu Tojo, Yutaka Suzuki, Takahiko Murayama, Kazuhiro Ikeda, Sumio Sugano, Kaoru Yamawaki, Yuta Kogure, Yasuto Takeuchi, Masahide Seki, Masao Yano, Asuka Nakata, Tetsuo Ohta
Publikováno v:
Cancer Science
Cancer stem‐like cells (CSCs) induce drug resistance and recurrence of tumors when they experience DNA replication stress. However, the mechanisms underlying DNA replication stress in CSCs and its compensation remain unclear. Here, we demonstrate t
Publikováno v:
International Journal of Intelligent Transportation Systems Research. 19:34-43
With the spread of smartphones, accidents caused by “Simultaneous-Action” such as “Simultaneous-Walking” which is walking while operating a smartphone and “Simultaneous-Cycling” which is cycling while operating a smartphone are increasing
Autor:
Masataka Ito, Reiko Sakamoto, Dominic Chih-Cheng Voon, Mengjiao Li, Masahiko Kuroda, Arinobu Tojo, Noriko Gotoh, Koichi Akashi, Nobuaki Yoshida, Hideyuki Saya, Natsuko Kimura, Yasuto Takeuchi, Tatsunori Nishimura, Minoru Terashima, Takeshi Suzuki, Mizuki Yamamoto, Takahiko Murayama, Naoki Itano, Yukino Machida, Yusuke Inoue, Daisuke Iejima, Issay Kitabayashi, Koji Fujita, Jun-ichiro Inoue, Yuming Wang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Human breast cancer develops after a long period of latency under premalignant conditions. Strategies to target the premalignant conditions have yet to materialize since the molecular mechanisms remain obscure. Here, we discovered that F