Zobrazeno 1 - 10
of 357
pro vyhledávání: '"Takahiko, Shimizu"'
Autor:
Rahmawati Aisyah, Noriyasu Ohshima, Daiki Watanabe, Yoshiko Nakagawa, Tetsushi Sakuma, Felix Nitschke, Minako Nakamura, Koji Sato, Kaori Nakahata, Chihiro Yokoyama, Charlotte R. Marchioni, Thanutchaporn Kumrungsee, Takahiko Shimizu, Yusuke Sotomaru, Toru Takeo, Naomi Nakagata, Takashi Izumi, Shinji Miura, Berge A. Minassian, Takashi Yamamoto, Masanobu Wada, Noriyuki Yanaka
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Glycerophosphocholine (GPC) is an important precursor for intracellular choline supply in phosphatidylcholine (PC) metabolism. GDE5/Gpcpd1 hydrolyzes GPC into choline and glycerol 3-phosphate; this study aimed to elucidate its physiological
Externí odkaz:
https://doaj.org/article/cb2483d665d74748b78e1920755b6628
Autor:
Ikko Sakamoto, Shuichi Shibuya, Hidetoshi Nojiri, Kotaro Takeno, Hiroshi Nishimune, Keisuke Yaku, Takashi Nakagawa, Muneaki Ishijima, Takahiko Shimizu
Publikováno v:
Antioxidants, Vol 13, Iss 11, p 1421 (2024)
Mitochondria and glycogen are co-distributed in skeletal muscles to regulate the metabolic status. Mitochondria are also redox centers that regulate the muscle function during exercise. However, the pathophysiological relationship between the mitocho
Externí odkaz:
https://doaj.org/article/7bf8fbb4ba8e43368ef6ee38150cd1d9
Autor:
Shota Tamagawa, Daisuke Sakai, Hidetoshi Nojiri, Yoshihiko Nakamura, Takayuki Warita, Erika Matsushita, Jordy Schol, Hazuki Soma, Shota Ogasawara, Daiki Munesada, Masato Koike, Takahiko Shimizu, Masato Sato, Muneaki Ishijima, Masahiko Watanabe
Publikováno v:
Redox Biology, Vol 71, Iss , Pp 103091- (2024)
Low back pain (LBP) is a pervasive global health concern, primarily associated with intervertebral disc (IVD) degeneration. Although oxidative stress has been shown to contribute to IVD degeneration, the underlying mechanisms remain undetermined. Thi
Externí odkaz:
https://doaj.org/article/902f516d23074c69809ad465ad9459d4
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 748 (2024)
PAPLAL, a mixture of platinum (nPt) and palladium (nPd) nanoparticles, is widely used as a topical agent because of its strong antioxidant activity. Allergic contact dermatitis (ACD) is one of the most common occupational skin diseases worldwide. How
Externí odkaz:
https://doaj.org/article/e19ccdaf69e041a2a466d4616de8b41f
Autor:
Yayoi Obata, Kazuma Murakami, Taiji Kawase, Kenji Hirose, Naotaka Izuo, Takahiko Shimizu, Kazuhiro Irie
Publikováno v:
ACS Omega, Vol 5, Iss 34, Pp 21531-21537 (2020)
Externí odkaz:
https://doaj.org/article/fb417b04a9af4aa3b1597a9b183e48de
Autor:
Aowen Zhuang, Christine Yang, Yingying Liu, Yanie Tan, Simon T. Bond, Shannen Walker, Tim Sikora, Adrienne Laskowski, Arpeeta Sharma, Judy B. de Haan, Peter J. Meikle, Takahiko Shimizu, Melinda T. Coughlan, Anna C. Calkin, Brian G. Drew
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102135- (2021)
Metabolic conditions such as obesity, insulin resistance and glucose intolerance are frequently associated with impairments in skeletal muscle function and metabolism. This is often linked to dysregulation of homeostatic pathways including an increas
Externí odkaz:
https://doaj.org/article/ae96313ccf2649e18f91a9351306e975
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3073 (2022)
Musculoskeletal disease can be a serious condition associated with aging that may lead to fractures and a bedridden state due to decreased motor function. In addition to exercise training to increase muscle mass, increasing muscle function with the i
Externí odkaz:
https://doaj.org/article/05344a7a6bcb46ab95aaca64193eab90
Autor:
Ruth E. Fulton, Jennifer N. Pearson-Smith, Christopher Q. Huynh, Timothy Fabisiak, Li-Ping Liang, Stefanos Aivazidis, Brigit A. High, Georgia Buscaglia, Timothy Corrigan, Robert Valdez, Takahiko Shimizu, Manisha N. Patel
Publikováno v:
Neurobiology of Disease, Vol 158, Iss , Pp 105470- (2021)
Mitochondrial superoxide (O2−) production is implicated in aging, neurodegenerative disease, and most recently epilepsy. Yet the specific contribution of neuronal O2− to these phenomena is unclear. Here, we selectively deleted superoxide dismutas
Externí odkaz:
https://doaj.org/article/05ca107846c64e9d90c8cc9f4faa05a3
Autor:
Sudha Sharma, Susmita Bhattarai, Hosne Ara, Grace Sun, Daret K. St Clair, Md Shenuarin Bhuiyan, Christopher Kevil, Megan N. Watts, Paari Dominic, Takahiko Shimizu, Kevin J. McCarthy, Hong Sun, Manikandan Panchatcharam, Sumitra Miriyala
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101740- (2020)
Electrophilic aldehyde (4-hydroxynonenal; 4-HNE), formed after lipid peroxidation, is a mediator of mitochondrial dysfunction and implicated in both the pathogenesis and the progression of cardiovascular disease. Manganese superoxide dismutase (MnSOD
Externí odkaz:
https://doaj.org/article/2e80799244c74b9aa7443b34abaa0a5a
Autor:
Daniel Andergassen, Markus Muckenhuber, Philipp C Bammer, Tomasz M Kulinski, Hans-Christian Theussl, Takahiko Shimizu, Josef M Penninger, Florian M Pauler, Quanah J Hudson
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009151 (2020)
[This corrects the article DOI: 10.1371/journal.pgen.1008268.].
Externí odkaz:
https://doaj.org/article/e3b0679cd3ec4221a2c5e55dd74ef5f1