Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Takahiko, Murata"'
Autor:
Florence Massiera, Perla Saint-Marc, Josiane Seydoux, Takahiko Murata, Takuya Kobayashi, Shuh Narumiya, Philippe Guesnet, Ez-Zoubir Amri, Raymond Negrel, Gérard Ailhaud
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 2, Pp 271-279 (2003)
High fat intake is associated with fat mass gain through fatty acid activation of peroxisome proliferator-activated receptors δ and γ, which promote adipogenesis. We show herein that, compared to a combination of specific agonists to both receptors
Externí odkaz:
https://doaj.org/article/47992fd004a24cb58505437401a59729
Publikováno v:
Scientific Reports
Mid-infrared sensors detect infrared radiation emitted from objects, and are actually widely used for monitoring gases and moisture as well as for imaging objects at or above room temperature. Infrared photodetectors offer fast detection, but many de
Autor:
Satoshi Nishimura, Koji Eto, Hidenori Hirose, Shinji Hirata, Takahiko Murata, Daisuke Suzuki, Sou Nakamura, Ryoko Jono-Ohnishi, Akira Sawaguchi, Naoshi Sugimoto
Publikováno v:
Stem Cells Translational Medicine
Donor-independent platelet concentrates for transfusion can be produced in vitro from induced pluripotent stem cells (iPSCs). However, culture at 37°C induces ectodomain shedding on platelets of glycoprotein Ibα (GPIbα), the von Willebrand factor
Autor:
Masahiro Amakawa, Takahiko Murata, Takuji Tanaka, Yasushi Matsumura, Tango Handa, Koji Takeuchi, Yoshihide Miyake, Katsuhiko Konishi, Yusuke Watanabe
Publikováno v:
European Journal of Pharmacology. 754:179-189
Agonists for EP4 receptor, a prostaglandin E2 receptor subtype, appear to be a promising therapeutic strategy for ulcerative colitis (UC) due to their anti-inflammatory and epithelial regeneration activities. However, the clinical development of oral
Autor:
Yoshio Matsui, Hideki Amano, Hidero Kitasato, Masataka Majima, Shuh Narumiya, Takahiko Murata, Yoshiya Ito, Tastunori Suzuki, Robert M. Senior, Shintaro Kato, Yukitoshi Satoh, Izumi Hayashi, Yukihiko Sugimoto, Fumihiro Ogawa
Publikováno v:
Cancer Science. 100:2318-2324
Cyclooxygenase (COX)-2 is known to correlate with poor cancer prognosis and to contribute to tumor metastasis. However, the precise mechanism of this phenomenon remains unknown. We have previously reported that host stromal prostaglandin E(2) (PGE(2)
Publikováno v:
Journal of the Neurological Sciences. 267:66-69
To investigate whether mitochondrial oxidative damage contributes to the pathogenesis of sporadic amyotrophic lateral sclerosis (sALS), we used high-performance liquid chromatography with an electrochemical detector to measure the concentrations of t
Autor:
Tomoyuki Furuyashiki, Yoshiki Miyachi, Takahiko Murata, Miyako Nagamachi, Shuh Narumiya, Kenji Kabashima, Toshiyuki Matsuoka, Kitipong Soontrapa, Daiji Sakata, Eri Segi-Nishida
Publikováno v:
The Journal of Experimental Medicine
Prostaglandin E2 (PGE2) exerts its actions via four subtypes of the PGE receptor, EP1–4. We show that mice deficient in EP1 exhibited significantly attenuated Th1 response in contact hypersensitivity induced by dinitrofluorobenzene (DNFB). This phe
Publikováno v:
European Journal of Neurology. 13:346-350
Long-term or high-dose L-DOPA therapy in patients with Parkinson's disease (PD) may accelerate degeneration of dopaminergic neurons, possibly by increasing oxidative stress. To investigate the effects of cabergoline on peroxynitrite-mediated oxidativ
Publikováno v:
IEEE Journal of Solid-State Circuits. 39:2426-2430
This paper presents new MOS image sensor technologies that realize ultra-small pixel size, i.e., 2.25/spl times/2.25 /spl mu/m/sup 2/, with high sensitivity and low supply voltage. A 1/4-inch 2-Mpixel MOS image sensor has been developed by a new pixe
Autor:
Takashi Ohno, Sumito Mizuguchi, Takahiko Murata, Izumi Hayashi, Shuh Narumiya, Katsuharu Arai, Kouju Kamata, Masataka Majima, Takeo Saeki, K. Saigenji
Publikováno v:
Gut. 52:1242-1249
Background: We previously reported that endogenous prostaglandin I 2 , generated by a mild irritant, sensitised calcitonin gene related peptide (CGRP) containing sensory nerves and facilitated the release of CGRP and gastric mucosal protection agains