Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Takahide Nishi"'
Autor:
Shingo Takiguchi, Takahide Nishi
Publikováno v:
Synlett. 34:277-282
In synthesizing novel derivatives of the natural cyclic peptides the ogipeptins, we established a simple and practical solid-phase peptide synthesis and macrocyclization method. By using this method, it became possible to obtain skeleton-modified ogi
Publikováno v:
Synlett. 33:2033-2037
A practical method for synthesizing 7-azaserotonin and 7-azamelatonin was developed by using 3-bromo-5-methoxy-1-tosyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-2-ol as a starting material. This compound is a useful reactant for the formal C3-electrophili
Publikováno v:
Organic Letters. 24:4935-4938
The first total synthesis of ogipeptin A was achieved. Recently, using the advanced Marfey's method, we determined the absolute configuration patterns of three β-hydroxy-α,γ-diaminobutyric acids (β-OH Dabs) composing ogipeptins. On the basis of t
Publikováno v:
Synlett.
We herein describe a practical synthetic method to access oxazolidinone-2,3-fused indoline and azaindoline derivatives via one-pot cyclization. These derivatives, which contain sp3-hybridized carbons, may be useful as new scaffolds in medicinal chemi
Publikováno v:
Tetrahedron. 135:133328
Publikováno v:
Synlett. 32:1034-1038
We describe a practical method for synthesizing heterocycle-2,3-fused indoline or azaindoline derivatives through haloetherification and cyclization. We applied this method in syntheses of six- to eight-membered heterocycle-2,3-fused indoline and aza
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 78:597-607
Publikováno v:
Synlett. 30:2247-2252
We disclose a silver-mediated intramolecular Friedel–Crafts-type cyclization of 2-benzyloxy-3-bromoindolines to afford an untapped family of isochromeno[3,4-b]indolines and 3-arylindoles, in which deformylative arylation of 2-(4-methoxybenzyloxy)-3
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:199-203
We herein report a practical one-step glucuronidation method by biotransformation using Streptomyces sp. SANK 60895. This novel direct method of biotransformation has been shown to be more practical and scalable for glucuronidation than previously re
Publikováno v:
Tetrahedron. 113:132760