Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Takahide Matsushima"'
Autor:
Yoshiaki Ito, Tokio Matsuzaki, Fumiaki Ayabe, Sho Mokuda, Ryota Kurimoto, Takahide Matsushima, Yusuke Tabata, Maiko Inotsume, Hiroki Tsutsumi, Lin Liu, Masahiro Shinohara, Yoko Tanaka, Ryo Nakamichi, Keiichiro Nishida, Martin K. Lotz, Hiroshi Asahara
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Osteoarthritis is caused by an imbalance between extracellular matrix synthesis and degradation. Here, the authors show that both strands of microRNA-455, -5p and -3p, target HIF2α and regulate cartilage homeostasis, and show that overexpression of
Externí odkaz:
https://doaj.org/article/f8166b7edfce46f19f52746332d9254e
Autor:
Hiroki Tsutsumi, Ryota Kurimoto, Ryo Nakamichi, Tomoki Chiba, Takahide Matsushima, Yuta Fujii, Risa Sanada, Tomomi Kato, Kana Shishido, Yuriko Sakamaki, Tsuyoshi Kimura, Akio Kishida, Hiroshi Asahara
Publikováno v:
Journal of Tissue Engineering, Vol 13 (2022)
Tendons and ligaments are essential connective tissues that connect the muscle and bone. Their recovery from injuries is known to be poor, highlighting the crucial need for an effective therapy. A few reports have described the development of artific
Externí odkaz:
https://doaj.org/article/8a19bcd27337489aa78fffa7de09e233
Autor:
Hiroto Yamamoto, Yutaro Uchida, Tomoki Chiba, Ryota Kurimoto, Takahide Matsushima, Maiko Inotsume, Chihiro Ishikawa, Haiyan Li, Takashi Shiga, Masafumi Muratani, Tokujiro Uchida, Hiroshi Asahara
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0236771 (2020)
BackgroundsSevoflurane is a most frequently used volatile anesthetics, but its molecular mechanisms of action remain unclear. We hypothesized that specific genes play regulatory roles in brain exposed to sevoflurane. Thus, we aimed to evaluate the ef
Externí odkaz:
https://doaj.org/article/03e466b9c9a146999024338ee148f070
Autor:
Tatsuya Hoshino, Koichiro Suzuki, Takahide Matsushima, Naoki Yamakawa, Toshiharu Suzuki, Tohru Mizushima
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76306 (2013)
Amyloid-β peptide (Aβ) plays an important role in the pathogenesis of Alzheimer's disease (AD). Aβ is generated by the secretase-mediated proteolysis of β-amyloid precursor protein (APP), and cleared by enzyme-mediated degradation and phagocytosi
Externí odkaz:
https://doaj.org/article/1b71a41dfba94657bf2dda69f5b3cc97
Autor:
Maiko Inotsume, Tomoki Chiba, Takahide Matsushima, Ryota Kurimoto, Mitsuyo Nakajima, Tomomi Kato, Kana Shishido, Lin Liu, Koichi Kawakami, Hiroshi Asahara
Publikováno v:
FEBS Letters. 597:975-984
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d1a3cbfad1edfa664e6b091f3a28fe8
https://doi.org/10.1002/1873-3468.14605
https://doi.org/10.1002/1873-3468.14605
Autor:
Naoto Washihira, Mika Murakami, Miho Nakamura, Sho Fujii, Takahide Matsushima, Hiroshi Asahara, Akio Kishida, Tadao Tanabe, Tsuyoshi Kimura, Mako Kobayashi, Masaya Yamamoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb1159f6294d331426c6a8d9824b8ded
https://doi.org/10.2139/ssrn.4420015
https://doi.org/10.2139/ssrn.4420015
Autor:
Hiroto Yamamoto, Yutaro Uchida, Ryota Kurimoto, Tomoki Chiba, Takahide Matsushima, Yoshiaki Ito, Maiko Inotsume, Kohei Miyata, Kenta Watanabe, Masaki Inada, Naoki Goshima, Tokujiro Uchida, Hiroshi Asahara
Publikováno v:
The Journal of biological chemistry. 299(1)
Hypoxia-inducible factor 1α (HIF1α) is a transcription factor that regulates angiogenesis under hypoxic conditions. To investigate the posttranscriptional regulatory mechanism of HIF1α, we performed a cell-based screening to reveal potential cis-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b6eb77415af6d99fb2478edff4f2b2
https://pubmed.ncbi.nlm.nih.gov/36509142
https://pubmed.ncbi.nlm.nih.gov/36509142
Autor:
Yukiho Kobayashi, Keiji Moriyama, Kana Shishido, Tomoki Chiba, Hiroki Tsutsumi, Tsutomu Matsumoto, Ryo Nakamichi, Lisa Yagasaki, Ryota Kurimoto, Takahide Matsushima, Tomomi Kato, Takayuki Miyazaki, Hiroshi Asahara, Kaho Takada
Publikováno v:
Journal of Bone and Mineral Metabolism. 39:780-786
The periodontal ligament (PDL) plays an important role in orthodontic tooth movement; however, the underlying molecular mechanism remains unclear. We have previously reported that the Mohawk homeobox (Mkx), a tendon-specific transcription factor, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b3c3c39e85d8d8b52284215ff132555
https://doi.org/10.1007/s00774-021-01233-2
https://doi.org/10.1007/s00774-021-01233-2
Publikováno v:
Transactions of the Institute of Systems, Control and Information Engineers. 34:69-80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f24e523ddec1ef9a466b385465e9a87a
https://doi.org/10.5687/iscie.34.69
https://doi.org/10.5687/iscie.34.69
Autor:
Takayuki, Miyazaki, Ryota, Kurimoto, Tomoki, Chiba, Takahide, Matsushima, Ryo, Nakamichi, Hiroki, Tsutsumi, Kaho, Takada, Lisa, Yagasaki, Tomomi, Kato, Kana, Shishido, Yukiho, Kobayashi, Tsutomu, Matsumoto, Keiji, Moriyama, Hiroshi, Asahara
Publikováno v:
Journal of bone and mineral metabolism. 39(5)
The periodontal ligament (PDL) plays an important role in orthodontic tooth movement; however, the underlying molecular mechanism remains unclear. We have previously reported that the Mohawk homeobox (Mkx), a tendon-specific transcription factor, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69cd4f2caad4e6fe4ef82d74bfe1514d
https://pubmed.ncbi.nlm.nih.gov/33988755
https://pubmed.ncbi.nlm.nih.gov/33988755