Cell death induced by NLRP3-palmitate axis impairs pulmonary damage tolerance and aggravates immunopathology during obesity-tuberculosis comorbidity.

Autor: Palma Albornoz SP; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil., Fraga-Silva TF; Department of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil., de Carvalho RV; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil., Rodrigues TS; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil., Gembre AF; Department of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil., de Oliveira RS; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil., de Souza FM; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil., Corrêa GF; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil., Ramalho LN; Department of Pathology and Legal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil., Carlos D; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil.; Department of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil., de Almeida DC; Department of Immunology, Institute of Biomedical Sciences IV, University of Sao Paulo, São Paulo, Brazil., Câmara NO; Department of Immunology, Institute of Biomedical Sciences IV, University of Sao Paulo, São Paulo, Brazil., Zamboni DS; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil.; Department of Cell Biology, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil., Takahashi VN; Department of Clinical Analysis, Toxicology and Bromatology, School of Pharmaceutical Sciences of Ribeirão Preto, University of Sao Paulo, São Paulo, Brazil., Sorgi CA; Department of Clinical Analysis, Toxicology and Bromatology, School of Pharmaceutical Sciences of Ribeirão Preto, University of Sao Paulo, São Paulo, Brazil., Faccioli LH; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil.; Department of Clinical Analysis, Toxicology and Bromatology, School of Pharmaceutical Sciences of Ribeirão Preto, University of Sao Paulo, São Paulo, Brazil., Medeiros AI; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil.; Department of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, São Paulo, Brazil., Costa DL; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil.; Department of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil., Bonato VL; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil.; Department of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, São Paulo, Brazil.

Publikováno v: The Journal of pathology [J Pathol] 2023 Mar; Vol. 259 (3), pp. 291-303. Date of Electronic Publication: 2023 Jan 03.

PD-L1 ⁺ neutrophils contribute to injury-induced infection susceptibility.

Autor: Thanabalasuriar A; Microbial Sciences, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.; McGill University, Department of Pharmacology and Therapeutics, Faculty of Medicine, Montreal, QC Canada., Chiang AJ; Dynamic Omics, Antibody Discovery and Protein Engineering (ADPE), R&D, AstraZeneca, Gaithersburg, MD, USA., Morehouse C; Microbial Sciences, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Camara M; Microbial Sciences, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Hawkins S; Animal Sciences and Technologies, Clinical Pharmacology and Safety Sciences, AstraZeneca, Gaithersburg, MD, USA., Keller AE; Microbial Sciences, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Koksal AC; Dynamic Omics, Antibody Discovery and Protein Engineering (ADPE), R&D, AstraZeneca, Gaithersburg, MD, USA., Caceres CS; Microbial Sciences, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Berlin AA; Respiratory and Immunology, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Holoweckyj N; Research and Early Development, Oncology R&D, AstraZeneca, Gaithersburg, MD, USA., Takahashi VN; Microbial Sciences, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Cheng L; Research and Early Development, Oncology R&D, AstraZeneca, Gaithersburg, MD, USA., de Los Reyes M; Research and Early Development, Oncology R&D, AstraZeneca, Gaithersburg, MD, USA., Pelletier M; Microbial Sciences, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Patera AC; Microbial Sciences, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Sellman B; Microbial Sciences, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Hess S; Dynamic Omics, Antibody Discovery and Protein Engineering (ADPE), R&D, AstraZeneca, Gaithersburg, MD, USA., Marelli M; Dynamic Omics, Antibody Discovery and Protein Engineering (ADPE), R&D, AstraZeneca, Gaithersburg, MD, USA., Boo CC; Dynamic Omics, Antibody Discovery and Protein Engineering (ADPE), R&D, AstraZeneca, Gaithersburg, MD, USA., Cohen TS; Microbial Sciences, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., DiGiandomenico A; Microbial Sciences, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA. antonio.digiandomenico@astrazeneca.com.

Publikováno v: Science advances [Sci Adv] 2021 Mar 05; Vol. 7 (10). Date of Electronic Publication: 2021 Mar 05 (Print Publication: 2021).

Investigation of 15q11-q13, 16p11.2 and 22q13 CNVs in autism spectrum disorder Brazilian individuals with and without epilepsy.

Autor: Moreira DP; Centro de Pesquisas sobre o Genoma Humano e Células Tronco, Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo, Brasil., Griesi-Oliveira K; Centro de Pesquisas sobre o Genoma Humano e Células Tronco, Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo, Brasil., Bossolani-Martins AL; Departamento de Biologia Molecular, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brasil., Lourenço NC; Centro de Pesquisas sobre o Genoma Humano e Células Tronco, Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo, Brasil., Takahashi VN; Centro de Pesquisas sobre o Genoma Humano e Células Tronco, Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo, Brasil., da Rocha KM; Centro de Pesquisas sobre o Genoma Humano e Células Tronco, Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo, Brasil., Moreira ES; Centro de Pesquisas sobre o Genoma Humano e Células Tronco, Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo, Brasil., Vadasz E; Instituto de Psiquiatria do Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brasil., Meira JG; Centro de Pesquisas sobre o Genoma Humano e Células Tronco, Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo, Brasil., Bertola D; Centro de Pesquisas sobre o Genoma Humano e Células Tronco, Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo, Brasil; Instituto da Criança da Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brasil., O'Halloran E; Academic Centre on Rare Diseases, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland., Magalhães TR; Academic Centre on Rare Diseases, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland., Fett-Conte AC; Departamento de Biologia Molecular, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brasil., Passos-Bueno MR; Centro de Pesquisas sobre o Genoma Humano e Células Tronco, Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo, Brasil.

Publikováno v: PloS one [PLoS One] 2014 Sep 25; Vol. 9 (9), pp. e107705. Date of Electronic Publication: 2014 Sep 25 (Print Publication: 2014).

A West Nile virus recombinant protein vaccine that coactivates innate and adaptive immunity.

Autor: McDonald WF; VaxInnate Corporation, New Haven, CT 06511, USA. wmcdonald@vaxinnate.com, Huleatt JW, Foellmer HG, Hewitt D, Tang J, Desai P, Price A, Jacobs A, Takahashi VN, Huang Y, Nakaar V, Alexopoulou L, Fikrig E, Powell TJ

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2007 Jun 01; Vol. 195 (11), pp. 1607-17. Date of Electronic Publication: 2007 Apr 17.