Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Takaharu Okada"'
Autor:
Keitaro Fukuda, Yoshihiro Ito, Yuki Furuichi, Takeshi Matsui, Hiroto Horikawa, Takuya Miyano, Takaharu Okada, Mark van Logtestijn, Reiko J. Tanaka, Atsushi Miyawaki, Masayuki Amagai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The stratum corneum is the outermost skin layer with a vital role in skin barrier function. It is comprised of dead keratinocytes (corneocytes) and is known to maintain its thickness by shedding cells, although, the precise mechanisms that s
Externí odkaz:
https://doaj.org/article/67513ada9a894969804586d1f76040a0
Autor:
Yukihiro Ohya, Toshiya Ebata, Yusei Ohshima, Tsugunobu Andoh, Mitsutoshi Tominaga, Yoko Kataoka, Yoshinori Fukui, Nobuyuki Ebihara, Shunji Hasegawa, Shigetoshi Kobayashi, Yutaka Morisawa, Norihiro Inoue, Masami Narita, Sakae Kaneko, Ken Igawa, Takeshi Nakahara, Yozo Ishiuji, Takaharu Okada, Masanori Fujii, Hiroshi Kawasaki, Hiroyuki Irie, Miho Shiratori-Hayashi, Hiroyuki Murota
Publikováno v:
Journal of Cutaneous Immunology and Allergy, Vol 7 (2024)
Background: The nature of itch sensation varies depending upon the patient and the disease. However, few studies have focused on verbal expressions describing itch of atopic dermatitis (AD) in quality.Objectives: To investigate itch quality in patien
Externí odkaz:
https://doaj.org/article/4f846319ae3b45e19745494433ba0a6c
Autor:
Madoka Nakajima, Shigeki Yamada, Masakazu Miyajima, Kaito Kawamura, Chihiro Akiba, Hiroaki Kazui, Etsuro Mori, Masatsune Ishikawa, The SINPHONI-2 Investigators, Masaaki Hashimoto, Hideki Origasa, Haruko Yamamoto, Hajime Arai, Koreaki Mori, Shigenobu Nakamura, Tamotsu Miki, Kazunari Ishii, Hiroji Miyake, Nobumasa Kuwana, Naoyuki Samejima, Daisuke Kita, Takahiko Tokuda, Mitsuhito Mase, Satoru Mori, Yoshinaga Kajimoto, Teiji Nakayama, Osamu Hirai, Masatoshi Takeda, Chia-Cheng Chang, Isao Date, Masahiro Kameda, Takaharu Okada, Junichiro Hamada, Mitsuya Watanabe, Mitsunobu Kaijima, Souichi Sunada, Yoshihumi Hirata
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background: We analyzed the predictive value of the tap test (TT) on the outcome of cerebrospinal fluid (CSF) shunting in patients with idiopathic normal pressure hydrocephalus (iNPH) and cognitive impairment up to 12 months postoperatively.Methods:
Externí odkaz:
https://doaj.org/article/1681ab6ab71a4c4287244bd8b3e526e4
Autor:
Daisuke Takahashi, Naomi Hoshina, Yuma Kabumoto, Yuichi Maeda, Akari Suzuki, Hiyori Tanabe, Junya Isobe, Takahiro Yamada, Kisara Muroi, Yuto Yanagisawa, Atsuo Nakamura, Yumiko Fujimura, Aiko Saeki, Mizuki Ueda, Ryohtaroh Matsumoto, Hanako Asaoka, Julie M. Clarke, Yohsuke Harada, Eiji Umemoto, Noriko Komatsu, Takaharu Okada, Hiroshi Takayanagi, Kiyoshi Takeda, Michio Tomura, Koji Hase
Publikováno v:
EBioMedicine, Vol 58, Iss , Pp 102913- (2020)
Background: Rheumatoid arthritis (RA) is a chronic debilitating autoimmune disorder with a high prevalence, especially in industrialized countries. Dysbiosis of the intestinal microbiota has been observed in RA patients. For instance, new-onset untre
Externí odkaz:
https://doaj.org/article/1f63ab6004a146fa8e8dd2e2492aca39
Autor:
Wen-Hsuan W. Lin, William C. Adams, Simone A. Nish, Yen-Hua Chen, Bonnie Yen, Nyanza J. Rothman, Radomir Kratchmarov, Takaharu Okada, Ulf Klein, Steven L. Reiner
Publikováno v:
Cell Reports, Vol 13, Iss 10, Pp 2203-2218 (2015)
Metazoan sibling cells often diverge in activity and identity, suggesting links between growth signals and cell fate. We show that unequal transduction of nutrient-sensitive PI3K/AKT/mTOR signaling during cell division bifurcates transcriptional netw
Externí odkaz:
https://doaj.org/article/14178e8238a842baa15557f6ad3eeaef
Autor:
Miho Ushijima, Takehito Uruno, Akihiko Nishikimi, Fumiyuki Sanematsu, Yasuhisa Kamikaseda, Kazufumi Kunimura, Daiji Sakata, Takaharu Okada, Yoshinori Fukui
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
A hallmark of humoral immune responses is the production of antibodies. This process involves a complex cascade of molecular and cellular interactions, including recognition of specific antigen by the B cell receptor (BCR), which triggers activation
Externí odkaz:
https://doaj.org/article/0d39915c0a3441c7a7131c4a644ff3e3
Publikováno v:
Materials, Vol 9, Iss 1, p 12 (2015)
Inactivated Hemagglutinating Virus of Japan Envelope (HVJ-E) was immobilized on electrospun nanofibers of poly(ε-caprolactone) by layer-by-layer (LbL) assembly technique. The precursor LbL film was first constructed with poly-L-lysine and alginic ac
Externí odkaz:
https://doaj.org/article/3a2ca9ab3b5f43589adf98eca8b2c4e7
Autor:
Takaharu Okada, Mark J Miller, Ian Parker, Matthew F Krummel, Margaret Neighbors, Suzanne B Hartley, Anne O'Garra, Michael D Cahalan, Jason G Cyster
Publikováno v:
PLoS Biology, Vol 3, Iss 6, p e150 (2005)
Interactions between B and T cells are essential for most antibody responses, but the dynamics of these interactions are poorly understood. By two-photon microscopy of intact lymph nodes, we show that upon exposure to antigen, B cells migrate with di
Externí odkaz:
https://doaj.org/article/8974c5cbbb18411492ced432ef0142e8
Autor:
Kazuyuki Sugita, Eiji Nagata, Hisaaki Sakate, Takaharu Okada, Shinya Adachi, Shogo Kamo, Akinobu Matsuzawa
Publikováno v:
Synthesis. 55:663-669
In this article, we report the synthesis of (±)-5-epi-vetiverianine A. The key reactions, including a rhodium-catalyzed coupling reaction and an oxidative phenolic cyclization, allow for efficient and stereoselective access to (±)-5-epi-vetiveriani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7845c2bb8cbee4b92d9fd0759a5635df
https://doi.org/10.1055/a-1947-6049
https://doi.org/10.1055/a-1947-6049
Autor:
Toshiya Ebata, Yukihiro Ohya, Yusei Ohshima, Tsugunobu Andoh, Mitsutoshi Tominaga, Yoko Kataoka, Yoshinori Fukui, Nobuyuki Ebihara, Shunji Hasegawa, Shigetoshi Kobayashi, Yutaka Morisawa, Norihiro Inoue, Masami Narita, Sakae Kaneko, Ken Igawa, Takeshi Nakahara, Yozo Ishiuji, Takaharu Okada, Masanori Fujii, Hiroshi Kawasaki
Publikováno v:
Arerugi: Japanese Journal of Allergology; 2024, Vol. 73 Issue 2, p171-179, 9p