Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Takaharu Mizutani"'
Autor:
Takaharu Mizutani1 (AUTHOR) takaharu@mbr.nifty.com, Mizutani, Takaharu1 (AUTHOR)
Publikováno v:
Journal of Environmental & Public Health. 2009, p1-9. 9p. 2 Diagrams, 1 Chart, 5 Graphs.
Autor:
Masatoshi Masuda, Takaharu Mizutani
Publikováno v:
Drug Metabolism Letters. 1:306-310
We have developed an easy and sensitive method to measure P-glycoprotein (P-gp) activity using [gamma-(32)P]ATP and charcoal. This method utilizes the nature of adsorption of organic phosphate to charcoal. The standard assay method is as follows: the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9077c4b0a6cb92a54f2bd0d2379f7bd6
https://doi.org/10.2174/187231207783221448
https://doi.org/10.2174/187231207783221448
Publikováno v:
Gene. 392:7-13
Eukaryotic tRNA genes are transcribed by RNA polymerase III. These tRNA genes are generally predicted using computer programs, and 620 tRNA genes in the Arabidopsis thaliana genome are currently annotated. However, no effort has been made to assay wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc4ae9464722498be9446be12d62d94
https://doi.org/10.1016/j.gene.2006.10.011
https://doi.org/10.1016/j.gene.2006.10.011
Autor:
Takaharu Mizutani, Hitomi Mori
Publikováno v:
Journal of Health Science. 53:302-310
The serum concentration of valproic acid (VPA) in epilepsy patients decreased by the administration of carbapenem antibiotics, such as meropenem, panipenem or imipenem, to a sub-therapeutic level. Studies to explain the decrease were carried out usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6f0b7b91252dee29b2042aa689eb590
https://doi.org/10.1248/jhs.53.302
https://doi.org/10.1248/jhs.53.302
Autor:
Takaharu Mizutani, Masatoshi Masuda
Publikováno v:
Journal of Health Science. 53:282-290
Multiple drug resistant protein 1 (MDR1), P-glycoprotein, plays a role in the blood-brain barrier, preventing drug distribution into the brain, and in cancer chemotherapy. MDR1 is composed of two repeated fragments and there are six transmembrane dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abab68655bf1dd9aba93336c94af7775
https://doi.org/10.1248/jhs.53.282
https://doi.org/10.1248/jhs.53.282
Autor:
Yasuko Murakami, Takashi Osaka, Takashi Shinkawa, Asuka Hattori, Senya Matsufuji, Toshiaki Isobe, Tamiko Matsufuji, Yuta Tanaka, Takaharu Mizutani
Publikováno v:
JOURNAL OF HEALTH SCIENCE. 53:682-691
Autoimmune hepatitis (AIH) serum contains autoantibodies against solubl el iver antigen/liver and pancreas (SLA/LP), a protein that interacts with the selenocysteine (Sec)-tRNA Sec .W e investigated the infl uence of AIH serum on Sec production. Two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cc0694d9859aa67fabe976becfc94ed
https://doi.org/10.1248/jhs.53.682
https://doi.org/10.1248/jhs.53.682
Publikováno v:
Biochemical Pharmacology. 71:693-701
Previous study showed noinduction of the reporter gene (-3174/+14) of UGT1A1 in HepG2 by bilirubin, but induction by dexamethasone (DEX). This induction was enhanced seven-fold by the co-expression of human glucocorticoid receptor (GR) and was inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ea463f9dbc3709d96ea9ed4ec7cfb7
https://doi.org/10.1016/j.bcp.2005.11.014
https://doi.org/10.1016/j.bcp.2005.11.014
Autor:
Haruo Nukaya, Teruhisa Hirayama, Haruyuki Mori, Takaharu Mizutani, Tomomi Horibe, Satoshi Yoshida, Gao Ning, Kazuhiko Takahashi, Tetsushi Watanabe, Masaharu Asanoma
Publikováno v:
Genes and Environment. 28:160-166
An organic extract from surface soil collected at a park in Nagoya, Aichi prefecture, which showed extremely high mutagenicity in Salmonella typhimurium TA98 in the absence of a mammalian metabolic system (S9 mix), was investigated to identify the ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1673649e55eac33737ed057784ef736b
https://doi.org/10.3123/jemsge.28.160
https://doi.org/10.3123/jemsge.28.160
Publikováno v:
Journal of Health Science. 52:549-557
We have reported that erythrosine (ET), a xanthene dye, inhibited uridine 5-diphosphate (UDP)glucuronosyltransferase 1A6 (UGT1A6). In order to clarify the structure-inhibition relationships of these xanthene dyes, the inhibitory effect of xanthene dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3104194e452106e8940c7a5bbaf67722
https://doi.org/10.1248/jhs.52.549
https://doi.org/10.1248/jhs.52.549