Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Takafumi Ichikawa"'
Autor:
Fumitaka Kawakami, Motoki Imai, Yuki Isaka, Mark R. Cookson, Hiroko Maruyama, Makoto Kubo, Matthew J. Farrer, Makoto Kanzaki, Rei Kawashima, Tatsunori Maekawa, Shun Tamaki, Yoshifumi Kurosaki, Fumiaki Kojima, Kenichi Ohba, Takafumi Ichikawa
Publikováno v:
FEBS Open Bio, Vol 13, Iss 12, Pp 2200-2214 (2023)
Epidemiological studies have shown that abnormalities of glucose metabolism are involved in leucine‐rich repeat kinase 2 (LRRK2)‐associated Parkinson's disease (PD). However, the physiological significance of this association is unclear. In the p
Externí odkaz:
https://doaj.org/article/b45a9cfcdb4646e59fbb5d9ee09970be
Autor:
Sirithip Chuaijit, Chuchard Punsawad, Veronica Winoto, Waluga Plaingam, Itti Kongkaew, Atidtaya Phetcharat, Takafumi Ichikawa, Makoto Kubo, Fumitaka Kawakami, Aman Tedasen, Moragot Chatatikun
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction:Garcinia atroviridis has been used for traditional medicines, healthy foods and tea. The chemical compositions and biological activities of fruit, stem bark and root have been widely studied. However, the phytochemical components and the
Externí odkaz:
https://doaj.org/article/12da3f2205644afc9ed28d9d551aae34
Autor:
Kunwadee Noonong, Moragot Chatatikun, Sirirat Surinkaew, Manas Kotepui, Rahni Hossain, Kingkan Bunluepuech, Chanittha Noothong, Aman Tedasen, Wiyada Kwanhian Klangbud, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Yoshimasa Kitagawa, Hiroshi Ichikawa, Takuro Kanekura, Suriyan Sukati, Voravuth Somsak, Lunla Udomwech, Takafumi Ichikawa, Veeranoot Nissapatorn, Jitbanjong Tangpong, Hiroko P. Indo, Hideyuki J. Majima
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
SignificanceThis review discusses the coronavirus disease 2019 (COVID-19) pathophysiology in the context of diabetes and intracellular reactions by COVID-19, including mitochondrial oxidative stress storms, mitochondrial ROS storms, and long COVID.Re
Externí odkaz:
https://doaj.org/article/ac5917ed72de48e197935d19fec494b7
Autor:
Daisuke Masuda, Ikuo Nakanishi, Kei Ohkubo, Hiromu Ito, Ken-ichiro Matsumoto, Hiroshi Ichikawa, Moragot Chatatikun, Wiyada Kwanhian Klangbud, Manas Kotepui, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Hirofumi Matsui, Jitbanjong Tangpong, Takafumi Ichikawa, Toshihiko Ozawa, Hsiu-Chuan Yen, Daret K. St Clair, Hiroko P. Indo, Hideyuki J. Majima
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 128 (2024)
Questions about which reactive oxygen species (ROS) or reactive nitrogen species (RNS) can escape from the mitochondria and activate signals must be addressed. In this study, two parameters, the calculated dipole moment (debye, D) and permeability co
Externí odkaz:
https://doaj.org/article/2f9fcb72f1c247bc85463ff752e569d2
Autor:
Rei Kawashima, Shun Tamaki, Yusuke Hara, Tatsunori Maekawa, Fumitaka Kawakami, Takafumi Ichikawa
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14971 (2023)
Non-steroidal anti-inflammatory drugs (NSAIDs), which are antipyretics and analgesics, cause gastrointestinal disorders, such as inflammation and ulcers. To prescribe NSAIDs more safely, it is important to clarify the mechanism of NSAID-induced gastr
Externí odkaz:
https://doaj.org/article/d76e06fa4e06419b9960e7fd5d7edca1
Autor:
Keita Aida, Kentaro Kamiya, Nobuaki Hamazaki, Kohei Nozaki, Takafumi Ichikawa, Takeshi Nakamura, Masashi Yamashita, Shota Uchida, Emi Maekawa, Jennifer L. Reed, Minako Yamaoka-Tojo, Atsuhiko Matsunaga, Junya Ako
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Six-minute walk distance (6MWD) of 300 and 400 m are important targets of functional capacity. The present study was performed to determine cutoff values of physical function associated with 6MWD 65 years (median age, 75: interquartile range
Externí odkaz:
https://doaj.org/article/6452f4e466ef489cab2095927b2655f4
Autor:
Masashi Yamashita, Kentaro Kamiya, Atsuhiko Matsunaga, Tadashi Kitamura, Nobuaki Hamazaki, Takafumi Ichikawa, Shota Uchida, Takumi Noda, Naoya Yanagi, Emi Maekawa, Minako Yamaoka‐Tojo, Junya Ako, Kagami Miyaji
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 2, Pp 1054-1063 (2022)
Abstract Background Low skeletal muscle area or density, such as myosteatosis, identified on computed tomography (CT) is associated with poor prognosis in patients with cardiovascular diseases. However, there is a lack of evidence regarding the clini
Externí odkaz:
https://doaj.org/article/896ea1e269b3410b844ef88e8d0ca006
Autor:
Takumi Noda, Kentaro Kamiya, Nobuaki Hamazaki, Kohei Nozaki, Takafumi Ichikawa, Masashi Yamashita, Shota Uchida, Kensuke Ueno, Emi Maekawa, Tasuku Terada, Jennifer L. Reed, Minako Yamaoka-Tojo, Atsuhiko Matsunaga, Junya Ako
Publikováno v:
Experimental Gerontology, Vol 171, Iss , Pp 112021- (2023)
Objectives: We investigated whether SARC-F scores were associated with motor function, quality of life (QOL) related to physical function, and prognosis in older patients with cardiovascular disease (CVD) and cognitive impairment. Methods: This was a
Externí odkaz:
https://doaj.org/article/4ea3557322854be8a0e5f9455fab8066
Autor:
Fumiaki Kojima, Hiroki Sekiya, Yuka Hioki, Hitoshi Kashiwagi, Makoto Kubo, Masaki Nakamura, Shotaro Maehana, Yoshitaka Imamichi, Koh-ichi Yuhki, Fumitaka Ushikubi, Hidero Kitasato, Takafumi Ichikawa
Publikováno v:
Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-24 (2022)
Abstract Background Microsomal prostaglandin E synthase-1 (mPGES-1) is a key enzyme that acts downstream of cyclooxygenase and plays a major role in inflammation by converting prostaglandin (PG) H2 to PGE2. The present study investigated the effect o
Externí odkaz:
https://doaj.org/article/78235e4fb4724385b2106c700040599e
Autor:
Kensuke Ueno, Kentaro Kamiya, Nobuaki Hamazaki, Kohei Nozaki, Takafumi Ichikawa, Masashi Yamashita, Shota Uchida, Naoya Yanagi, Emi Maekawa, Minako Yamaoka‐Tojo, Atsuhiko Matsunaga, Junya Ako
Publikováno v:
ESC Heart Failure, Vol 8, Iss 6, Pp 5092-5101 (2021)
Abstract Aims High‐sensitivity cardiac troponin T (hs‐cTnT) and B‐type natriuretic peptide (BNP) are associated with prognosis and severity in patients with heart failure (HF); however, their association with physical function is unclear. This
Externí odkaz:
https://doaj.org/article/ae93c1c1185e43daa8fa865275ba9827