Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Takafumi ISHIHARA"'
Autor:
Yasuhiro Fukunaka, Takayuki Homma, Takahiro Oyanagi, Masahiro Kunimoto, Kazuki Nakajima, Nobufumi Matsuo, Takafumi Ishihara
Publikováno v:
ECS Transactions. 64:91-97
Elimination of boron species via solvent extraction with 2,2,4-trimethyl-1,3-pentandiaol was engaged in a flow-type device into which the aqueous solution dissolving diatomaceous earth, a candidate of the resource for high-purity silicon material. Th
Autor:
Tetsuya Sugiyama, Mizuo Miyazaki, Tsunehiko Ikeda, Masato Sakaguchi, Shinji Takai, Yulin Yao, Takafumi Ishihara, Hitoshi Sakaguchi
Publikováno v:
Current Eye Research. 24:325-331
Two pathways for the formation of angiotensin II (Ang II) in local tissues are known to exist, one involving angiotensin-converting enzyme (ACE), and the other in which chymase plays a role. It has been shown that chymase activity is present in monke
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1545:146-152
A low molecular weight protein complexed with chymase was isolated from hamster cheek pouch tissues. This protein had an apparent molecular mass of about 10 kDa on SDS-PAGE and the N-terminal sequence showed some homology to secretory leukocyte prote
Autor:
Mizuo Miyazaki, Kazumasa Takao, Naotaka Shiota, Shinji Takai, Takafumi Ishihara, Keifu Song, Kazuo Nishimura
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1427:74-81
Human chymase from vascular tissues was purified to homogeneity by heparin affinity and gel filtration chromatography. Treatment of human chymase with endoglycosidase F resulted in cleavage of the carbohydrate moiety yielding a deglycosylation produc
Publikováno v:
Japanese Journal of Pharmacology. 81:404-407
Chymase is a chymotrypsin-like protease localized in mast cells in complexes with heparin. In the present study, we demonstrated that suramin, a hexasulfonated naphthylurea used as an anti-cancer drug, inhibits the activity of purified human chymase
Autor:
Toshio Tatsuoka, Tomochika Ohno, Kenji Suzuki, K. Aisaka, Fumio Satoh, Seiji Miyano, Takafumi Ishihara, Kunihiro Sumoto, Ryoko Ogino, Manami Kuroki
Publikováno v:
Chemical and Pharmaceutical Bulletin. 44:132-138
Two new series of 1-(1, 4-benzoquinon-2-yl)-1, 2, 3, 4-tetrahydronaphthalenes (3, 4) were synthesized for evaluation of their pharmacological activities. These compounds showed significant anti-lipid peroxidation (ALP) activities with rat brain homog
Autor:
Ryoko Ogino, Manami Kuroki, Seiji Miyano, Kunihiro Sumoto, K. Aisaka, Tomochika Ohno, Toshio Tatsuoka, Fumio Satoh, Kenji Suzuki, Takafumi Ishihara
Publikováno v:
ChemInform. 27
Two new series of 1-(1, 4-benzoquinon-2-yl)-1, 2, 3, 4-tetrahydronaphthalenes (3, 4) were synthesized for evaluation of their pharmacological activities. These compounds showed significant anti-lipid peroxidation (ALP) activities with rat brain homog
Autor:
Toshio Tatsuoka, K. Suzuki, Tomoko Miyazaki, Teruyoshi Inoue, T. Murakami, Takafumi Ishihara, K. Aisaka, Kunihiro Sumoto, Ryoko Ogino, Fumio Satoh, Manami Kuroki, Seiji Miyano
Publikováno v:
ChemInform. 27
Autor:
Tomoko Miyazaki, K. Suzuki, Takafumi Ishihara, Toshio Tatsuoka, Ryoko Ogino, Seiji Miyano, Kunihiro Sumoto, Fumio Satoh
Publikováno v:
ChemInform. 28
Publikováno v:
Archives of Biochemistry and Biophysics. 298:726-730
(6 R )-5,6,7,8-Tetrahydro- l -biopterin (R-THBP) is a cofactor not only for aromatic amino acid hydroxylases in mammalian tissues but also for nitric oxide synthase (NOS) induced by endotoxins or cytokines in some kinds of cells. Recently it has been