Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Takafumi, Kuzuya"'
Autor:
Kiyofumi Yamada, Yoshihiko Watarai, Yuko Miwa, Kenta Iwasaki, Takaaki Kobayashi, Kazuharu Uchida, Takafumi Kuzuya, Hideyuki Kushihara
Publikováno v:
Biological & Pharmaceutical Bulletin. 39:1085-1090
Cyclosporine (CSA), which is one of the substrates of ATP binding cassette subfamily B member 1 (ABCB1), is widely used as an immunosuppressant in patients undergoing transplantation. The expression level of P-glycoprotein on lymphocytes that is enco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7fdd23af0fe593f434176b0abb6799
https://doi.org/10.1248/bpb.b15-00690
https://doi.org/10.1248/bpb.b15-00690
Autor:
Takafumi Kuzuya, Yoshihiko Watarai, Akio Katayama, Takaaki Kobayashi, Kazuharu Uchida, Yuko Miwa, Kiyofumi Yamada, Kenta Iwasaki, Masataka Haneda, Katsuo Amioka, Yoko Kurata
Publikováno v:
International Immunopharmacology. 22:384-391
Although therapeutic drug monitoring based on blood concentration has been widely implemented in transplant recipients treated with immunosuppressive agents, clinical adverse events such as rejection, infection or drug-induced toxicity caused by inap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e250d335e139471e45d318a70d3284
https://doi.org/10.1016/j.intimp.2014.07.022
https://doi.org/10.1016/j.intimp.2014.07.022
Autor:
Shoichiro Sembon, Takafumi Kuzuya, Takaaki Kobayashi, Shunichi Suzuki, Shoichi Maruyama, Haruko Ogawa, Koji Yamamoto, Satoko Yazaki, Masataka Haneda, Yuko Miwa, Michiko Hashimoto, Daiichiro Fuchimoto, D Liu, Tadashi Furusawa, Masaki Iwamoto, Takaharu Nagasaka, Akira Onishi, Takatsugu Oishi, Kenta Iwasaki
Publikováno v:
Xenotransplantation. 19:82-91
For long-term xenograft survival, coagulation control is one of the remaining critical issues. Our attention has been directed toward human thrombomodulin (hTM), because it is expected to exhibit the following beneficial effects on coagulation contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d35703c462b1fbd90e1dc19c16886ed9
https://doi.org/10.1111/j.1399-3089.2012.00696.x
https://doi.org/10.1111/j.1399-3089.2012.00696.x
Autor:
Takaaki Kobayashi, Takafumi Kuzuya, Kazuharu Uchida, Hayato Iwase, Yasuhiro Kodera, Yuko Miwa, Asami Takeda, Yoshihiko Watarai, Masataka Haneda, Kenta Iwasaki, Kunio Morozumi, Akimasa Nakao, Akio Katayama
Publikováno v:
Transplantation. 91:191-198
Background. Regulatory T cells (Tregs) have been suggested to be deeply associated with immune tolerance and long-term graft survival in transplantation. Some recipients with stable graft function (ST) could possibly minimize immunosuppression during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece5738843de2fb05d98132fdc5675b6
https://doi.org/10.1097/tp.0b013e3181ffbab4
https://doi.org/10.1097/tp.0b013e3181ffbab4
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 35:679-684
Summary What is known and objective: Total knee and hip joint replacement has a high risk of postoperative nausea and vomiting (PONV), and steroid cover is used for cases associated with autoimmune diseases. Our aim is to evaluate the antiemetic effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e678c90fea1d890e63966c9e57913f2e
https://doi.org/10.1111/j.1365-2710.2009.01141.x
https://doi.org/10.1111/j.1365-2710.2009.01141.x
Autor:
Akimasa Nakao, Takaharu Nagasaka, Yuko Miwa, Tadashi Furusawa, Akira Onishi, Takaaki Kobayashi, Kazuharu Uchida, Haruko Ogawa, Kenji Kadomatsu, Shunichi Suzuki, Shoichi Maruyama, D Liu, Satoko Yazaki, Michiko Hashimoto, Takafumi Kuzuya, Shoichiro Sembon, Masaki Iwamoto, Daiichiro Fuchimoto, Takatsugu Oishi
Publikováno v:
Xenotransplantation. 16:511-521
Yazaki S, Iwamoto M, Onishi A, Miwa Y, Suzuki S, Fuchimoto D, Sembon S, Furusawa T, Hashimoto M, Oishi T, Liu D, Nagasaka T, Kuzuya T, Maruyama S, Ogawa H, Kadomatsu K, Uchida K, Nakao A, Kobayashi T. Successful cross-breeding of cloned pigs expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03eed31e942e62c416be554f6f986c03
https://doi.org/10.1111/j.1399-3089.2009.00549.x
https://doi.org/10.1111/j.1399-3089.2009.00549.x
Autor:
Takafumi Kuzuya, Akira Onishi, Kazuharu Uchida, Kenji Kadomatsu, Takaharu Nagasaka, Yuko Miwa, D Liu, Akimasa Nakao, Masaki Iwamoto, Yu-Teh Li, Haruko Ogawa, Takaaki Kobayashi, Shoichi Maruyama
Publikováno v:
Transplant Immunology. 20:132-138
Background ABO incompatibility in organ transplantation is still a high risk factor for antibody-mediated rejection, despite the progress in effective treatments. We have explored the possibility of using the enzyme to remove the blood type A/B antig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf17638556a2bbce97a9d92e03d86ec
https://doi.org/10.1016/j.trim.2008.09.007
https://doi.org/10.1016/j.trim.2008.09.007
Autor:
Itsuo Yokoyama, Takaaki Kobayashi, Takaharu Nagasaka, Takafumi Kuzuya, Y Ma, D Liu, Akimasa Nakao, Tadashi Oikawa, Kunio Morozumi, Yuko Miwa, Kazuharu Uchida
Publikováno v:
Biological and Pharmaceutical Bulletin. 29:336-342
The clinical significance of cyclosporine (CsA) concentration 2 h postdose (C(2)) monitoring is widely recognized in organ transplantation, because C(2) value is considered to be a predictable surrogate marker of full area under the concentration-tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f8f264398aacae048a237b088d700a
https://doi.org/10.1248/bpb.29.336
https://doi.org/10.1248/bpb.29.336
Autor:
Yasunobu Shimano, Akimasa Nakao, Kazuharu Uchida, O Takeuchi, D Liu, Takafumi Kuzuya, Takaharu Nagasaka, Yu Ma, Takaaki Kobayashi, Kunio Morozumi, Tadashi Oikawa, Yuko Miwa, Itsuo Yokoyama
Publikováno v:
Transplant International. 18:401-407
Mizoribine (MZ) inhibits the proliferation of lymphocytes selectively via inhibition of inosine monophosphate dehydrogenase, like mycophenolate mofetil (MMF). The clinical dosage of MZ (2-5 mg/kg) is much lower than that of MMF (20-60 mg/kg). The pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a9b2695449cb6acba02ec6da3edc8e
https://doi.org/10.1111/j.1432-2277.2004.00042.x
https://doi.org/10.1111/j.1432-2277.2004.00042.x
Autor:
Takaaki Kobayashi, Toshitaka Nabeshima, Akimasa Nakao, Takaharu Nagasaka, Takafumi Kuzuya, Itsuo Yokoyama, Natsuko Moriyama, Kazuharu Uchida
Publikováno v:
Transplantation. 76:865-868
BACKGROUND Cyclosporine A (CsA) is a critical immunosuppressive drug with a narrow therapeutic range and wide interindividual variation in its pharmacokinetics. Many factors, including P-glycoprotein (PGP), influence the oral bioavailability and inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5044b920b74fba116125e9a02fbbda6
https://doi.org/10.1097/01.tp.0000084873.20157.67
https://doi.org/10.1097/01.tp.0000084873.20157.67