Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Takae Toyoshima"'
Autor:
Kento Fukano, Kousho Wakae, Naganori Nao, Masumichi Saito, Akihito Tsubota, Takae Toyoshima, Hideki Aizaki, Hiroko Iijima, Takahiro Matsudaira, Moto Kimura, Koichi Watashi, Wataru Sugiura, Masamichi Muramatsu
Publikováno v:
Hepatology Communications; Dec2023, Vol. 7 Issue 12, p1-15, 15p
Autor:
Naoki Takeda, Takao Iwawaki, Tomo O. Ishikawa, Ryoko Akai, Ken Ichi Yamamura, Takae Toyoshima
Publikováno v:
Scientific Reports
Activating transcription factor 4 (ATF4) is a translationally activated protein that plays a role in cellular adaptation to several stresses. Because these stresses are associated with various diseases, the translational control of ATF4 needs to be e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8573fdbddd1d9bc989c96cb32d5c41a9
http://europepmc.org/articles/PMC5384252
http://europepmc.org/articles/PMC5384252
Autor:
Kiyoshi Ando, Kazuki Okuyama, Ai Kotani, Tomokatsu Ikawa, Kazuaki Yokoyama, Bernhard Gentner, Arinobu Tojo, Toyotaka Kawamata, Jun Lu, Harvey F. Lodish, Hiroshi Kawamoto, Daon Ha, Katsuto Hozumi, Ratanakanit Harnprasopwat, Riu Yamashita, Shusheng Wang, Takae Toyoshima, Bidisha Chanda
Publikováno v:
Proceedings of the National Academy of Sciences. 110:13410-13415
Lineage specification is thought to be largely regulated at the level of transcription, where lineage-specific transcription factors drive specific cell fates. MicroRNAs (miR), vital to many cell functions, act posttranscriptionally to decrease the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830dba61582a73f97844311e53c1ac8a
https://doi.org/10.1073/pnas.1220710110
https://doi.org/10.1073/pnas.1220710110
Autor:
Hitoshi Nagaoka, Kiyoshi Ando, Ai Kotani, Takae Toyoshima, Jun Lu, Tadayuki Sato, Kazuaki Yokoyama, Yasutoshi Agata, Naoya Nakamura, Masafumi Tanaka, Toyotaka Kawamata, Arinobu Tojo, Naoki Oyaizu
Publikováno v:
Blood. 119:3123-3127
Activation-induced cytidine deaminase (AID) is essential for class switch recombination and somatic hypermutation. Its deregulated expression acts as a genomic mutator that can contribute to the development of various malignancies. During treatment w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6681b9bef21d9c3eb2f3fbc1c0b380e6
https://doi.org/10.1182/blood-2011-01-327932
https://doi.org/10.1182/blood-2011-01-327932
Autor:
Takae Toyoshima, Kazuo Kinoshita, Masamichi Muramatsu, Taichiro Nonaka, Tomomitsu Doi, Tasuku Honjo
Publikováno v:
Proceedings of the National Academy of Sciences. 106:2747-2751
Activation-induced cytidine deaminase (AID) is essential for the class switch recombination (CSR) and somatic hypermutation (SHM) of Ig genes. Originally, AID was postulated to be an RNA-editing enzyme, because of its structural homology with a known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4830582a1e255d148b81e0224977f280
https://doi.org/10.1073/pnas.0812957106
https://doi.org/10.1073/pnas.0812957106
Autor:
Takae Toyoshima, Naoki Takeda, Ken Ichi Yamamura, Ryoko Akai, Mitsumi Suzuki, Tomo O. Ishikawa, Takao Iwawaki, Mayuko Yoshino, Daisuke Oikawa, Yosky Kataoka
Publikováno v:
Scientific Reports
Inflammation is a biological response associated with symptoms of various diseases and its study is important in gaining an understanding of the pathological conditions of such diseases and in making strategic plans for promoting healing. It is there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518fb1eb11b89c8cbc37d8983d0257e5
https://doi.org/10.1038/srep17205
https://doi.org/10.1038/srep17205
Autor:
Ai Kotani, Daon Ha, Takae Toyoshima, Harvey F. Lodish, Ratanakanit Harnprasopwat, Arinobu Tojo
Publikováno v:
PMC
MicroRNAs (miRNAs) are small non-coding RNAs that inhibit expression of specific target genes at the post-transcriptional level. Sequence variations in miRNA genes, including pri-miRNAs, pre-miRNAs and mature miRNAs, could potentially influence the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca49ce81300dad7339cbd54cc963420
https://orcid.org/0000-0002-7029-7415
https://orcid.org/0000-0002-7029-7415
Publikováno v:
International journal of hematology. 92(2)
MicroRNAs (miRNA) are small noncoding RNAs that posttranscriptionally regulate expression of target mRNAs. In animals, miRNAs control many developmental and physiological processes. It has recently revealed that miRNAs critically work in B cell devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d3008bc8a4879740e8e7460d17fa83
https://pubmed.ncbi.nlm.nih.gov/20614203
https://pubmed.ncbi.nlm.nih.gov/20614203
Autor:
Tasuku Honjo, Atsushi Takai, Tsutomu Chiba, Hiroshi Hiai, Kazuo Kinoshita, Munehiro Uemura, Il-mi Okazaki, Hiroyuki Marusawa, Yoko Kitawaki, Takae Toyoshima, S. Yamada
Publikováno v:
Oncogene. 28(4)
Activation-induced cytidine deaminase (AID), the only enzyme that is known to be able to induce mutations in the human genome, is required for somatic hypermutation and class-switch recombination in B lymphocytes. Recently, we showed that AID is impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752c98e4686eab1bbf80c69cccb2f07e
https://pubmed.ncbi.nlm.nih.gov/18997814
https://pubmed.ncbi.nlm.nih.gov/18997814
Autor:
Takae Toyoshima, Lu Jun, Kiyoshi Ando, Hozumi Katsuto, Ai Kotani, Kazuaki Yokoyama, Takashi Yahata
Publikováno v:
Blood. 120:50-50
Abstract 50 The Epstein-Barr virus (EBV) is one of the most major human pathogen that establish long-term latent, or chronic infections, which is associated with a heterogeneous group of lymphoma, including Burkitt's lymphoma, Hodgkin's lymphoma (HL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::846b051b43f0eb02a0f74e096b4e85a7
https://doi.org/10.1182/blood.v120.21.50.50
https://doi.org/10.1182/blood.v120.21.50.50