Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Takae Kiyama"'
Autor:
Christopher J. LaFargue, Paola Amero, Kyunghee Noh, Lingegowda S. Mangala, Yunfei Wen, Emine Bayraktar, Sujanitha Umamaheswaran, Elaine Stur, Santosh K. Dasari, Cristina Ivan, Sunila Pradeep, Wonbeak Yoo, Chunhua Lu, Nicholas B. Jennings, Vinod Vathipadiekal, Wei Hu, Anca Chelariu-Raicu, Zhiqiang Ku, Hui Deng, Wei Xiong, Hyun-Jin Choi, Min Hu, Takae Kiyama, Chai-An Mao, Rouba Ali-Fehmi, Michael J. Birrer, Jinsong Liu, Ningyan Zhang, Gabriel Lopez-Berestein, Vittorio de Franciscis, Zhiqiang An, Anil K. Sood
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Antiangiogenic treatment targeting the vascular endothelial growth factor (VEGF) pathway is a powerful tool to combat tumor growth and progression; however, drug resistance frequently emerges. We identify CD5L (CD5 antigen-like precursor) as
Externí odkaz:
https://doaj.org/article/a4cffeff90ca418b8ed9c213a7bf3531
Pou4f1-Tbr1 transcriptional cascade controls the formation of Jam2-expressing retinal ganglion cells
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
More than 40 retinal ganglion cell (RGC) subtypes have been categorized in mouse based on their morphologies, functions, and molecular features. Among these diverse subtypes, orientation-selective Jam2-expressing RGCs (J-RGCs) has two unique morpholo
Externí odkaz:
https://doaj.org/article/3f2a81bc56a741e68b422cec34dcfe21
Publikováno v:
Cells, Vol 11, Iss 14, p 2203 (2022)
The retina, the accessible part of the central nervous system, has served as a model system to study the relationship between energy utilization and metabolite supply. When the metabolite supply cannot match the energy demand, retinal neurons are at
Externí odkaz:
https://doaj.org/article/970c061b7b5041e783173fb83f17340c
Autor:
Takae Kiyama, Ching-Kang Chen, Steven W Wang, Ping Pan, Zhenlin Ju, Jing Wang, Shinako Takada, William H Klein, Chai-An Mao
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-23 (2018)
Abstract Background Mitochondrial dysfunction has been implicated in the pathologies of a number of retinal degenerative diseases in both the outer and inner retina. In the outer retina, photoreceptors are particularly vulnerable to mutations affecti
Externí odkaz:
https://doaj.org/article/86e23958dde9462c9e095325aaa44ae2
Autor:
Takae Kiyama, Ye Long, Ching-Kang Chen, Christopher M. Whitaker, Allison Shay, Hongyu Wu, Tudor C. Badea, Amir Mohsenin, Jan Parker-Thornburg, William H. Klein, Stephen L. Mills, Stephen C. Massey, Chai-An Mao
Publikováno v:
Cell Reports, Vol 27, Iss 3, Pp 900-915.e5 (2019)
Summary: In the mouse retina, more than 30 retinal ganglion cell (RGC) subtypes have been classified based on a combined metric of morphological and functional characteristics. RGCs arise from a common pool of retinal progenitor cells during embryoni
Externí odkaz:
https://doaj.org/article/9c325aa44e9d4b08967f1de839af1fac
Autor:
Tudor C. Badea, Ching-Kang Chen, Nicole Weber, Ping Pan, Christopher M. Whitaker, Chai-An Mao, Stephen C. Massey, Takae Kiyama
Publikováno v:
J Comp Neurol
The mammalian retina contains more than 40 retinal ganglion cell (RGC) subtypes based on their unique morphologies, functions, and molecular profiles. Among them, intrinsically photosensitive RGCs (ipRGCs) are the first specified RGC type emerging fr
Autor:
William H. Klein, Allison Shay, Amir Mohsenin, Christopher M. Whitaker, Stephen L. Mills, Takae Kiyama, Chai An Mao, Ye Long, Tudor C. Badea, Stephen C. Massey, Jan Parker-Thornburg, Hongyu Wu, Ching-Kang Chen
Publikováno v:
Cell Reports, Vol 27, Iss 3, Pp 900-915.e5 (2019)
Summary: In the mouse retina, more than 30 retinal ganglion cell (RGC) subtypes have been classified based on a combined metric of morphological and functional characteristics. RGCs arise from a common pool of retinal progenitor cells during embryoni
Autor:
Ching-Kang Chen, Takae Kiyama, Weber, Nicole, Whitaker, Christopher M., Ping Pan, Badea, Tudor C., Massey, Stephen C., Chai-An Mao
Publikováno v:
Journal of Comparative Neurology; Oct2021, Vol. 529 Issue 15, p3513-3532, 20p
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e83686 (2014)
Retinal ganglion cells (RGCs) play important roles in retinogenesis. They are required for normal retinal histogenesis and retinal cell number balance. Developmental RGC loss is typically characterized by initial retinal neuronal number imbalance and
Externí odkaz:
https://doaj.org/article/f31fe9a069f94eb282a10751f8e2bbac