Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Takaaki YAMAMURA"'
Autor:
Hiroshi Kuse, Takaaki Yamamura, Hirofumi Yuasa, Kinji Kobayashi, Toshihide Inui, Atsushi Koguchi, Azusa Okaniwa, Toshihisa Fujiwara, Yoshiaki Kawai
Publikováno v:
Journal of Toxicologic Pathology. 7:81-86
Scanning electron microscopic observation of the organ of Corti was conducted in kanamycin (KM)-treated beagle dogs, which were subjected to time lapse recording of auditory brainstem response (ABR). KM was administered subcutaneously 5 times per wee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c99219c5a358268548054d8243214c82
https://doi.org/10.1293/tox.7.81
https://doi.org/10.1293/tox.7.81
Autor:
Hirofumi Yuasa, Toshihide Inui, Tadao Serikawa, Takaaki Yamamura, Junzo Yamada, Yoshiaki Kawai, Azusa Okaniwa
Publikováno v:
Brain Research. 517:123-133
The spontaneously epileptic rat (SER), a mutant homozygous for both zitter and tremor genes, exhibits absence-like seizures and tonic convulsions without external stimulation from 7 to 8 weeks of age. Histopathological studies of the central nervous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b02c46b901c44418dd0c40e56499195
https://doi.org/10.1016/0006-8993(90)91017-b
https://doi.org/10.1016/0006-8993(90)91017-b
Autor:
Kazutaka Kawashima, Chisato Yamaguchi, Tomonari Nishimura, Tamiko Adachi, Tatsuya Honda, Takaaki Yamamura, Yoshifumi Sasaki, Toshihisa Fujiwara, Toshihide Inui, Kinji Kobayashi, Yuki Kuwamura, Noriaki Tanimoto, Hirofumi Yuasa, Atsushi Koguchi
Publikováno v:
The Journal of toxicological sciences. 27(3)
As a part of the ILSI-HESI Alternative to Carcinogenicity Testing (ACT) program, we performed a 26-week carcinogenetic study of nonmutagenic drug, ampicillin (ABPC) in Tg-rasH2 mice. ABPC was given to Tg-rasH2 mice (0, 350, 1000, 3000 mg/kg, p.o.) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d72e9a3cd7e0c57f1eb98cf7300e03
https://pubmed.ncbi.nlm.nih.gov/12238139
https://pubmed.ncbi.nlm.nih.gov/12238139
Publikováno v:
The Journal of toxicological sciences.
The present study was performed to determine whether testicular toxicity can be detected of the administration of adriamycin (ADR), an anticancer drug, for 2 weeks. ADR was intravenously administered to Slc:SD male rats at 1 mg/kg once a week for 4 o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162ce53e4788a2128048050566524cf9
https://pubmed.ncbi.nlm.nih.gov/11349460
https://pubmed.ncbi.nlm.nih.gov/11349460
Autor:
Takaaki Yamamura, Hiroshi Kuse, Yoshiaki Kawai, Naoki Hishida, Michishige Noguchi, Masaki Hori
Publikováno v:
The Journal of toxicological sciences. 22
The acute toxicity studies of taltirelin tetrahydrate (TA-0910), a new thyrotropin-releasing hormone (TRH) analogue, were performed in Slc:ddY mice, Slc:Wistar rats and beagle dogs of both sexes. The drug was administered to mice and rats by oral(p.o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cad03ef6fb43659db330d14e7b50a8f
https://pubmed.ncbi.nlm.nih.gov/9430092
https://pubmed.ncbi.nlm.nih.gov/9430092
Autor:
Toshihide Inui, Yuki Kuwamura, Yoshiaki Kawai, Takaaki Yamamura, Tomonari Nishimura, Pete Aughton
Publikováno v:
The Journal of toxicological sciences. 22
Oncogenicity studies of taltirelin tetrahydrate (TA-0910), a new thyrotropin-releasing hormone (TRH) analogue, were carried out on CD-1 mice and CD rats. Groups of 60 male and 60 female CD-1 mice received TA-0910, by oral gavage, at dosages of 5, 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac8a8cfc76e91fb284dc17ce1938911
https://pubmed.ncbi.nlm.nih.gov/9430099
https://pubmed.ncbi.nlm.nih.gov/9430099
Autor:
Kinji KOBAYASHI, Kazutaka KAWASHIMA, Yumiko KAWASHIMA, Takaaki YAMAMURA, Hiroshi KUSE, Yuzo ASANO, Yoshiaki KAWAI, Masaki HORI, Azusa OKANIWA, Tadao SERIKAWA, Junzo YAMADA
Publikováno v:
Jikken dobutsu. Experimental animals. 42(2)
In order to investigate the relationship between visual dysfunction and retinal DA metabolism in zitter rats and spontaneously epileptic rats (SER), we measured the amounts of retinal dopamine (DA) and its metabolites, 3,4-dihydroxyphenylacetic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e169d44e02bbafbf0f27e50953c5ae8
https://pubmed.ncbi.nlm.nih.gov/8519304
https://pubmed.ncbi.nlm.nih.gov/8519304
Autor:
Azusa Okaniwa, Fujio Fujinami, Akihiro Kojima, Takaaki Yamamura, Masakazu Takeshita, Yoshio Minato, Kazunori Imaizumi
Publikováno v:
Nihon juigaku zasshi. The Japanese journal of veterinary science. 52(1)
Nine out of 19 newborn pups from 4 litters died or euthanatized on day 10 to 17 after birth in a specific-pathogen-free beagle colony which had been established by cesarean section and bottle-feeding. Necropsy showed congestion and edema of the lungs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfab941dfc6f2033b9314c7c8b115481
https://pubmed.ncbi.nlm.nih.gov/2156100
https://pubmed.ncbi.nlm.nih.gov/2156100
Publikováno v:
Journal of Veterinary Medical Science. 54:779-780
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35d73acbc3ca3e59fe3869eaf4817b8
https://doi.org/10.1292/jvms.54.779
https://doi.org/10.1292/jvms.54.779
Publikováno v:
Journal of Toxicologic Pathology. 2:85-95
Initially, morphological and endocrinological features of the thyroid gland are reviewed in view of the recent progress in thyroidology. The second part of this article deals with morphology and hormone measurement in the rat following drug-induced a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f6b34012880994bb315106c2984ccb1
https://doi.org/10.1293/tox.2.85
https://doi.org/10.1293/tox.2.85