Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Takaaki Tsunematsu"'
Autor:
Shengjian Jin, Takaaki Tsunematsu, Taigo Horiguchi, Yasuhiro Mouri, Wenhua Shao, Keiko Miyoshi, Hiroko Hagita, Motoharu Sarubo, Natsumi Fujiwara, Guangying Qi, Naozumi Ishimaru, Yasusei Kudo
Publikováno v:
Cancer Medicine, Vol 12, Iss 24, Pp 22156-22169 (2023)
Abstract Background Comprehending the molecular mechanisms underlying head and neck squamous cell carcinoma (HNSCC) is vital for the development of effective treatment strategies. Deubiquitinating enzymes (DUBs), which regulate ubiquitin‐dependent
Externí odkaz:
https://doaj.org/article/b8b785699a9a4837967dc25a36773d99
Autor:
Shao Wenhua, Takaaki Tsunematsu, Masaaki Umeda, Hiroaki Tawara, Natsumi Fujiwara, Yasuhiro Mouri, Rieko Arakaki, Naozumi Ishimaru, Yasusei Kudo
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8510-8525 (2023)
Abstract It recently has been reported that partial‐epithelial–mesenchymal transition (p‐EMT) program is associated with metastasis in head and neck squamous cell carcinoma (HNSCC). We previously have identified POSTN (which encodes periostin)
Externí odkaz:
https://doaj.org/article/09aaa8792d644a6990442e78970657a6
Autor:
Mami Sato-Fukuba, Rieko Arakaki, Aya Ushio, Kunihiro Otsuka, Ruka Nagao, Shigefumi Matsuzawa, Hiroaki Tawara, Takaaki Tsunematsu, Naozumi Ishimaru
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPrimary Sjögren’s syndrome (pSS) is a systemic autoimmune disease that affects the function of exocrine glands, such as the lacrimal and the salivary glands. Extraglandular lesions and malignant lymphoma also occur during the progressi
Externí odkaz:
https://doaj.org/article/355d5854dc5a47e19901f09c97191eba
Autor:
Mami Sato, Rieko Arakaki, Hiroaki Tawara, Ruka Nagao, Hidetaka Tanaka, Kai Tamura, Yuhki Kawahito, Kunihiro Otsuka, Aya Ushio, Takaaki Tsunematsu, Naozumi Ishimaru
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
ObjectiveInnate lymphoid cells (ILCs), including natural killer (NK) cells, ILC1, ILC2, lymphoid tissue-inducer (LTi) cells, and ILC3 cell, play a key role in various immune responses. Primary Sjögren’s syndrome (pSS) is an autoimmune disease char
Externí odkaz:
https://doaj.org/article/56a4f49bc8b64752b478b705a065f41d
Autor:
Ajay Chatrath, Roza Przanowska, Shashi Kiran, Zhangli Su, Shekhar Saha, Briana Wilson, Takaaki Tsunematsu, Ji-Hye Ahn, Kyung Yong Lee, Teressa Paulsen, Ewelina Sobierajska, Manjari Kiran, Xiwei Tang, Tianxi Li, Pankaj Kumar, Aakrosh Ratan, Anindya Dutta
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-18 (2020)
Abstract Background While clinical factors such as age, grade, stage, and histological subtype provide physicians with information about patient prognosis, genomic data can further improve these predictions. Previous studies have shown that germline
Externí odkaz:
https://doaj.org/article/21ef6b3b0c234b24a63f33b4cf444aab
Publikováno v:
Viruses, Vol 14, Iss 7, p 1474 (2022)
Sjögren’s syndrome (SS) is an autoimmune disease especially targeting exocrine glands, such as the salivary and lacrimal glands. A radical therapy for SS based on its etiology has not been established because of the complex pathogenesis of the dis
Externí odkaz:
https://doaj.org/article/ff185c5f1e0a4b16979e91bf89256cfa
Autor:
Mayuko Ichimura-Shimizu, Soichiro Ishimaru, Christine (Yee-Yan) Wai, Takeo Minamikawa, Takaaki Tsunematsu, Aiko Endo, Takumi Kojima, Minoru Matsumoto, Tomoko Kobayashi, Satoshi Sumida, Takumi Kakimoto, Yuko Miyakami, Hirohisa Ogawa, Takeshi Oya, Koichi Tsuneyama
Publikováno v:
Applied Sciences, Vol 12, Iss 7, p 3566 (2022)
Background: Shellfish allergy is one of the most common food allergies. Recent studies have shown that sensitization to allergens via the skin is involved in the development of food allergies. In this study, a mouse model of shrimp allergy was genera
Externí odkaz:
https://doaj.org/article/8c92af1e65d54fe38e4181765bd2b409
Autor:
Penkhae Utaijaratrasmi, Kulthida Vaeteewoottacharn, Takaaki Tsunematsu, Pranisa Jamjantra, Sopit Wongkham, Chawalit Pairojkul, Narong Khuntikeo, Naozumi Ishimaru, Yongyut Sirivatanauksorn, Ananya Pongpaibul, Peti Thuwajit, Chanitra Thuwajit, Yasusei Kudo
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-14 (2018)
Abstract Background Cholangiocarcinoma (CCA) has an abundance of tumor stroma which plays an important role in cancer progression via tumor-promoting signals. This study aims to explore the microRNA (miRNA) profile of CCA-associated fibroblasts (CCFs
Externí odkaz:
https://doaj.org/article/58c536cf8d4a40d1a113300857ef0d2f
Autor:
Aya Ushio, Rieko Arakaki, Kunihiro Otsuka, Akiko Yamada, Takaaki Tsunematsu, Yasusei Kudo, Keiko Aota, Masayuki Azuma, Naozumi Ishimaru
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Macrophages (MΦs) are critical regulators of immune response and serve as a link between innate and acquired immunity. The precise mechanism of involvement of tissue-resident MΦs in the pathogenesis of autoimmune diseases is not clear. Here, using
Externí odkaz:
https://doaj.org/article/ad9ce62163654ed88b688092af19665b
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3239 (2021)
The relationship between autoimmunity and changes in intestinal microbiota is not yet fully understood. In this study, the role of intestinal microbiota in the onset and progression of autoimmune lesions in non-obese diabetic (NOD) mice was evaluated
Externí odkaz:
https://doaj.org/article/140908661401492f80ad3a1aec33a59f