Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Takaaki Oba"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Compelling evidence shows that the frequency of T cells in the tumor microenvironment correlates with prognosis as well as response to immunotherapy. However, considerable heterogeneity exists within tumor-infiltrating T cells, and significa
Externí odkaz:
https://doaj.org/article/c94c59d7608442afb2b75ec19481b43e
Autor:
Rajeev Sharma, Hongbin Chen, Takaaki Oba, Fumito Ito, Kristopher Attwood, Grace Dy, Eihab Abdelfatah, Lauren Polyakov, Joy Sarkar, Brahm Segal
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/a974234f31e447859b8bf29360478272
Autor:
Masatsugu Amitani, Takaaki Oba, Nami Kiyosawa, Hiroki Morikawa, Tatsunori Chino, Ai Soma, Tadafumi Shimizu, Koichi Ohno, Mayu Ono, Tokiko Ito, Toshiharu Kanai, Kazuma Maeno, Ken-ichi Ito
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background The skeletal muscle index (SMI), which is calculated as the ratio of skeletal muscle area at the third lumbar vertebral level divided by height squared, has been considered a prognostic factor in patients with breast cancer. Howev
Externí odkaz:
https://doaj.org/article/e96b5b24bc84458fb50f758faba7a7e3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Despite recent progress in therapeutic strategies, prognosis of metastatic triple-negative breast cancer (TNBC) remains dismal. Evidence suggests that the induction and activation of tumor-residing conventional type-1 dendritic cells (cDC1s)
Externí odkaz:
https://doaj.org/article/a47ce881037545fd9257a49e41ccbe12
Autor:
Fumine Tsukamoto, Koji Arihiro, Mina Takahashi, Ken-ichi Ito, Shozo Ohsumi, Seiki Takashima, Takaaki Oba, Masayuki Yoshida, Kazuki Kishi, Keisuke Yamagishi, Takayuki Kinoshita
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background The benefits of postoperative chemotherapy in patients with estrogen receptor (ER)-positive breast cancer remain unclear. The use of tumor grade, Ki-67, or ER expression failed to provide an accurate prognosis of the risk of relap
Externí odkaz:
https://doaj.org/article/3f42261e6f1d42f2bb5fcc6fdaaa5ceb
Autor:
Tadafumi Shimizu, Takaaki Oba, Tatsunori Chino, Ai Soma, Mayu Ono, Tokiko Ito, Toshiharu Kanai, Kazuma Maeno, Yoshinori Sato, Takeshi Uehara, Ken-ichi Ito
Publikováno v:
Thyroid Research, Vol 14, Iss 1, Pp 1-7 (2021)
Abstract Background Distant metastasis from papillary thyroid microcarcinoma (PTMC) is rare. Here we report a case of PTMC with multiple lung metastases. Case presentation A 64-year-old man presented to our hospital with abdominal pain. Computed tomo
Externí odkaz:
https://doaj.org/article/74f21cc881b24ba4b7d18bf3f9922d29
Autor:
Takayoshi Yamauchi, Toshifumi Hoki, Takaaki Oba, Vaibhav Jain, Hongbin Chen, Kristopher Attwood, Sebastiano Battaglia, Saby George, Gurkamal Chatta, Igor Puzanov, Carl Morrison, Kunle Odunsi, Brahm H. Segal, Grace K. Dy, Marc S. Ernstoff, Fumito Ito
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
There is an urgent need to discover blood-based biomarkers to predict response to immune checkpoint inhibitors (ICI). Here the authors show that effective ICI therapy correlates with increased frequency of circulating CX3CR1+CD8+ T cells in preclinic
Externí odkaz:
https://doaj.org/article/5ad9763c2d134ba4b389bb215a94772a
Autor:
Takaaki Oba, Mark D. Long, Tibor Keler, Henry C. Marsh, Hans Minderman, Scott I. Abrams, Song Liu, Fumito Ito
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Strategies to increase T cell infiltration within the tumor microenvironment could improve response to immune checkpoint blockade. Here the authors show that a combinatorial regimen based on Flt3L, radiotherapy, and TLR3/CD40 stimulation promotes int
Externí odkaz:
https://doaj.org/article/624c24703da040c89811cce847e51d8c
Autor:
Takaaki Oba, Kazuma Maeno, Daiya Takekoshi, Mayu Ono, Tokiko Ito, Toshiharu Kanai, Ken-ichi Ito
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background The prognostic nutritional index (PNI), which is an easily calculated nutritional index, is significantly associated with patient outcomes in various solid malignancies. This study aimed to evaluate the prognostic impact of PNI ch
Externí odkaz:
https://doaj.org/article/d84c5430bb4e4b74bf315d6f08e58d05
Autor:
Song Liu, Satoko Matsueda, Takaaki Oba, Fumito Ito, Kenichi Makino, Ryutaro Kajihara, Mark D Long, Kazunori Kanehira
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/84df69c6958746a3961bce3bf5a5d676