Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Takaaki OZAWA"'
Autor:
Daiki Goto, Kenji Yanishi, Takaaki Ozawa, Jun Yoshimura, Hirofumi Kawamata, Ayumu Fujioka, Tomotsugu Seki, Kan Zen, Satoaki Matoba
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 12 (2024)
Background Acute mesenteric ischemia is rare, and few large‐scale trials have evaluated endovascular therapy (EVT) and open surgical revascularization (OS). This study aimed to assess clinical outcomes after EVT or OS for acute superior mesenteric
Externí odkaz:
https://doaj.org/article/c3d165435b5b4caa80ff228f29caf00b
Autor:
Tatsuyuki Matsudaira, Sosuke Nakano, Yusuke Konishi, Shimpei Kawamoto, Ken Uemura, Tamae Kondo, Koki Sakurai, Takaaki Ozawa, Takatoshi Hikida, Okiru Komine, Koji Yamanaka, Yuki Fujita, Toshihide Yamashita, Tomonori Matsumoto, Eiji Hara
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Cellular senescence, a state of irreversible cell-cycle arrest caused by a variety of cellular stresses, is critically involved in age-related tissue dysfunction in various organs. However, the features of cells in the central nervous system
Externí odkaz:
https://doaj.org/article/d6b2fb2ed0004f7fb3c9b513eaae3a5e
Publikováno v:
Neuropsychopharmacology Reports, Vol 42, Iss 4, Pp 521-525 (2022)
Abstract Caffeine is the most widely consumed psychostimulant drug which could affect learning and memory acting through central adenosine receptors. Although caffeine has been suggested to impair the acquisition and the expression of auditory fear c
Externí odkaz:
https://doaj.org/article/ccc36840a44d401c9fea7e3f6f2319bc
Publikováno v:
Neuropsychopharmacology Reports, Vol 41, Iss 4, Pp 526-531 (2021)
Abstract Aim Acute N‐methyl‐D‐aspartate (NMDA) receptor antagonism is an important pharmacological animal model of schizophrenia. In previous studies, schizophrenia patients show impaired goal‐directed behavior in an outcome‐specific devalu
Externí odkaz:
https://doaj.org/article/3a4603df747e4ebba2d69877d50b1106
Functional organization of the midbrain periaqueductal gray for regulating aversive memory formation
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-9 (2021)
Abstract Innately aversive experiences produce rapid defensive responses and powerful emotional memories. The midbrain periaqueductal gray (PAG) drives defensive behaviors through projections to brainstem motor control centers, but the PAG has also b
Externí odkaz:
https://doaj.org/article/c88cd17ca161455abdcc225e028711ff
Autor:
Yoshiatsu Aomine, Koki Sakurai, Tom Macpherson, Takaaki Ozawa, Yoichi Miyamoto, Yoshihiro Yoneda, Masahiro Oka, Takatoshi Hikida
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Importin α3 (Gene: Kpna3, the ortholog of human Importin α4) is a member of the importin α family and participates in nucleocytoplasmic transport by forming trimeric complexes between cargo proteins and importin β1. Evidence from human studies ha
Externí odkaz:
https://doaj.org/article/5950c7e75ce74768bb30982df01a1325
Autor:
Koki Sakurai, Taichi Itou, Makiko Morita, Emiko Kasahara, Tetsuji Moriyama, Tom Macpherson, Takaaki Ozawa, Yoichi Miyamoto, Yoshihiro Yoneda, Atsuo Sekiyama, Masahiro Oka, Takatoshi Hikida
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Importin α1/KPNA1 is a member of the Importin α family widely present in the mammalian brain and has been characterized as a regulator of neuronal differentiation, synaptic functionality, and anxiety-like behavior. In humans, a de novo mutation of
Externí odkaz:
https://doaj.org/article/1985221431214bfd8e0df3309ab94647
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254570 (2021)
Spontaneous recognition tests, which utilize rodents' innate tendency to explore novelty, can evaluate not only simple non-associative recognition memory but also more complex associative memory in animals. In the present study, we investigated wheth
Externí odkaz:
https://doaj.org/article/ca744df6e34544c38e2c4e925ab190cf
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171629 (2017)
Hippocampal de novo mRNA and protein synthesis has been suggested to be critical for long-term spatial memory. However, its requirement in each memory process (i.e. encoding, consolidation and retrieval) and the differences in the roles of de novo mR
Externí odkaz:
https://doaj.org/article/3cec84e9ad7d41bd8c7b469f63b2ae74
Autor:
Jun, Shiraishi, Yuya, Asano, Yusuke, Kakei, Fumiaki, Ito, Jun, Yoshimura, Eisuke, Kataoka, Takaaki, Ozawa, Daisuke, Ito, Akiteru, Kojima, Masayoshi, Kimura, Eigo, Kishita, Yusuke, Nakagawa, Masayuki, Hyogo, Takahisa, Sawada
Publikováno v:
Minerva Cardiology and Angiology. 71
Although drug-coated balloon (DCB) -based stent-less percutaneous coronary intervention (PCI) for de novo lesions has attracted more attention, outcomes of the DCB procedure for hemodialysis (HD) patients are reported to be inferior to those for non-