Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Takaaki Nakamura"'
Autor:
Shun Yoshida, Takafumi Hasegawa, Takaaki Nakamura, Kazuki Sato, Naoto Sugeno, Shun Ishiyama, Kiyotoshi Sekiguchi, Muneshige Tobita, Atsushi Takeda, Masashi Aoki
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Since the identification of vacuolar protein sorting (VPS) 35, as a causative molecule for familial Parkinson’s disease (PD), retromer-mediated endosomal machinery has been a rising factor in the pathogenesis of the disease. The retromer c
Externí odkaz:
https://doaj.org/article/6f9f6bbeb9224731973eaf8ff56f8bcc
Autor:
Michinori Ezura, Akio Kikuchi, Nobuyuki Okamura, Aiko Ishiki, Takafumi Hasegawa, Ryuichi Harada, Shoichi Watanuki, Yoshihito Funaki, Kotaro Hiraoka, Toru Baba, Naoto Sugeno, Shun Yoshida, Junpei Kobayashi, Michiko Kobayashi, Ohito Tano, Shun Ishiyama, Takaaki Nakamura, Ichiro Nakashima, Shunji Mugikura, Ren Iwata, Yasuyuki Taki, Katsutoshi Furukawa, Hiroyuki Arai, Shozo Furumoto, Manabu Tashiro, Kazuhiko Yanai, Yukitsuka Kudo, Atsushi Takeda, Masashi Aoki
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Introduction: We aimed to determine whether in vivo tau deposits and monoamine oxidase B (MAO-B) detection using 18F-THK5351 positron emission tomography (PET) can assist in the differential distribution in patients with corticobasal syndrome (CBS),
Externí odkaz:
https://doaj.org/article/32c907a418364c868797fbcc1c7cd9a0
Publikováno v:
Clinical Case Reports, Vol 8, Iss 8, Pp 1594-1594 (2020)
Abstract The pathophysiological mechanism of resting tremor in Parkinson's disease remains obscure. Spinal/peripheral mechanisms may modulate oscillatory activity from central origin, thereby changing amplitude and frequency of tremor in Parkinson's
Externí odkaz:
https://doaj.org/article/4f4b71bd21b44bc19ccad24bce677bb7
Autor:
Takashi Uzu, Shin-Ichi Araki, Atsunori Kashiwagi, Masakazu Haneda, Daisuke Koya, Hiroki Yokoyama, Yasuo Kida, Motoyoshi Ikebuchi, Takaaki Nakamura, Masataka Nishimura, Noriko Takahara, Toshiyuki Obata, Nobuyuki Omichi, Katsuhiko Sakamoto, Ryosuke Shingu, Hideki Taki, Yoshio Nagai, Hiroaki Tokuda, Munehiro Kitada, Miwa Misawa, Akira Nishiyama, Hiroyuki Kobori, Hiroshi Maegawa, Shiga Committee for Preventing Diabetic Nephropathy
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0164936 (2016)
In patients with diabetes, albuminuria is a risk marker of end-stage renal disease and cardiovascular events. An increased renin-angiotensin system activity has been reported to play an important role in the pathological processes in these conditions
Externí odkaz:
https://doaj.org/article/adf3d8a2d62144fe9e04c3c18113be4e
Autor:
Takaaki Nakamura, Alison Fox-Robichaud, Ryuichi Kikkawa, Astunori Kashiwagi, Hideto Kojima, Mineko Fujimiya, Norman C.W. Wong
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 9, Pp 1709-1718 (1999)
Apolipoprotein (apo)A-I alone or as a component of high density lipoprotein particles has antiatherogenic properties. The age-dependent decline in abundance of this protein may underlie the higher risk for developing occlusive coronary artery disease
Externí odkaz:
https://doaj.org/article/524efa26957c41adb5fdbd8ad0f1cf60
Publikováno v:
Data Mining and Knowledge Discovery. 37:670-709
Publikováno v:
The Proceedings of the Fluids engineering conference. 2022:OS05-19
Publikováno v:
Endocrine Journal. 69:95-100
The etiology of central diabetes insipidus (DI) is classified into (1) idiopathic, (2) familial, and (3) secondary. Of these, familial central diabetes insipidus shows an autosomal dominant inheritance. We herein report a case in which this disease w
Autor:
Naoto Sugeno, Takafumi Hasegawa, Shun Ishiyama, Michinori Ezura, Akiko Matsunaga, Masamichi Ikawa, Akio Kikuchi, Masashi Aoki, Makoto Yoneda, Atsushi Takeda, Yasunari Nakamoto, Toru Baba, Takaaki Nakamura
Publikováno v:
Journal of Neurology. 268:4291-4295
Hashimoto’s encephalopathy with serum anti-NH2-terminal of α-enolase (NAE) antibodies occasionally displays clinical symptoms such as cerebellar ataxia and parkinsonism. We studied the frequency of anti-NAE antibodies in patients with Parkinson-pl
Autor:
Koichiro Shioya, Shun'ichiro Taniguchi, Yuji Seki, Takaaki Nakamura, Hitomi Shimizu, Tomio Matsumura
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 85:324-331
APS001F is a strain of Bifidobacterium longum genetically engineered to express cytosine deaminase that converts 5-fluorocytosine (5-FC) to 5-fluorouracil. In the present study, antitumor effects of APS001F plus 5-FC (APS001F/5-FC) in combination wit