Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Takaaki Kurinomaru"'
Autor:
Kayoko Hayashihara-Kakuhou, Ayano Fukuhara, Kimitoshi Takeda, Yoshihiko Abe, Naoki Ishii, John F. Carpenter, Sho Fujiwara, Susumu Uchiyama, Tsutomu Ueda, Takaaki Kurinomaru
Publikováno v:
Journal of Pharmaceutical Sciences. 111:41-50
To reduce the risk of infection during intravitreal injections, the external surface of prefilled syringes (PFSs) must be sterilized. Usually, ethylene oxide (EO) gas or vaporized hydrogen peroxide (VHP) is used for sterilization. More recently, nitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7776c1217c8f167ec9816cda6e908194
https://doi.org/10.1016/j.xphs.2021.09.003
https://doi.org/10.1016/j.xphs.2021.09.003
Publikováno v:
ACS applied materialsinterfaces.
Untethered mobile micromachines hold great promise in the development of effective and minimally invasive therapies. Although diverse medical micromachines for specific applications have been developed over the past few decades, the coordinated actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5d6b8ee986dd81ff22ddca9e694d0e
https://pubmed.ncbi.nlm.nih.gov/35822220
https://pubmed.ncbi.nlm.nih.gov/35822220
Publikováno v:
Materials Horizons. 7:877-884
Despite biomimetic artificial tissues having the potential to greatly contribute to regenerative medicine and drug screening, technologies for constructing functional tissue architectures in a sophisticated manner have not yet been fully developed. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a613ca29e895d51ebd4c410ce76e8fa
https://doi.org/10.1039/c9mh01799b
https://doi.org/10.1039/c9mh01799b
Publikováno v:
Analytical Chemistry. 91:13933-13939
Since the discovery of the active DNA demethylation pathway in mammals, numerous efforts have been made to distinguish epigenetic cytosine variants, including 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79eb930704ce66f057fd3680d6b2d8b
https://doi.org/10.1021/acs.analchem.9b03423
https://doi.org/10.1021/acs.analchem.9b03423
Publikováno v:
Analytica Chimica Acta. 1043:107-114
We report the quantitative analysis of 5-methylcytosine, a representative epigenetic modification in genomic DNA, with an enzyme-linked immunosorbent assay (ELISA). We synthesized a novel hetero-bifunctional linker molecule consisting of nitrogen mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bde948cbc0d2e9bd23ef57239d8d52
https://doi.org/10.1016/j.aca.2018.09.008
https://doi.org/10.1016/j.aca.2018.09.008
Publikováno v:
Molecular Catalysis. 455:32-37
α-Chymotrypsin (CHT) is a serine protease that hydrolyzes peptide bonds at the carboxyl end of hydrophobic amino acids. It has been shown that the enzyme activity of CHT increases one order of magnitude in the presence of some types of amine compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::377546c8f8f41bbab06e17e3e5eae392
https://doi.org/10.1016/j.mcat.2018.05.023
https://doi.org/10.1016/j.mcat.2018.05.023
Publikováno v:
Current Protocols in Nucleic Acid Chemistry. 77
Immobilization of DNA is an important step in relation to DNA-based biosensors and bioassays with multiple applications. This unit describes synthesis and applications of novel bifunctional linker molecules containing nitrogen mustard and one of two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41c5cd53f6069a998ba177514975547
https://doi.org/10.1002/cpnc.85
https://doi.org/10.1002/cpnc.85
Autor:
Ryoji Kurita, Takaaki Kurinomaru
Publikováno v:
Analytical Methods. 9:1537-1549
The determination of epigenetic modification, especially that of 5-methylcytosine in the CpG sequence in mammals, has attracted attention because it should prove valuable in a wide range of research fields including diagnosis, drug discovery and ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb08d0dceec10856a0fa52bfbf17b4e8
https://doi.org/10.1039/c7ay00232g
https://doi.org/10.1039/c7ay00232g
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 133:S432-S438
The enzyme activity of α-chymotrypsin (ChT) has been known to increase with the addition of polyelectrolytes and amine compounds that combine with oppositely charged substrates. Enzyme hyperactivation is thought to occur by changing the electrostati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e1a4a0d86cd20b67c3ab2aefb8deff9
https://doi.org/10.1016/j.molcatb.2017.03.006
https://doi.org/10.1016/j.molcatb.2017.03.006
Publikováno v:
Colloid and Polymer Science. 294:1551-1556
Recently, on/off switching of enzyme activity by noncovalent complexation with polyelectrolytes has been developed for biotechnological application. However, noncovalent complexation based on electrostatic interaction is unfavorable at high ionic str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17dd9a02b145d11ceef5c97c5a81d516
https://doi.org/10.1007/s00396-016-3916-5
https://doi.org/10.1007/s00396-016-3916-5