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pro vyhledávání: '"Takaaki Iiboshi"'
Autor:
Takaaki Iiboshi, Kuniomi Tachibana, Masashi Kusaba, Nobutoki Takamune, Shibata Hideaki, Shozo Shoji, Mamoru Umeda, Shogo Misumi, Tadashi Nakasone, Masafumi Endo, Daisuke Nakayama, Ryouzaburo Mukai
Publikováno v:
The Journal of Immunology. 176:463-471
A synthetic cycloimmunogen targeting the HIV-1 coreceptor CCR5 was evaluated for its capacity to induce CCR5-specific Abs with anti-HIV-1 activity in cynomolgus macaques. The cyclic closed-chain dodecapeptide (cDDR5) mimicking the conformation-specif