Zobrazeno 1 - 10
of 359
pro vyhledávání: '"Takaaki, Fujii"'
Autor:
Daisuke Kato, Hiroyuki Kameda, Naoya Kinota, Takaaki Fujii, Bai Xiawei, Zhou Simi, Yoshiki Takai, Simon Chau, Yoshiki Miyasaka, Tomoji Mashimo, Yoichiro Abe, Masato Yasui, Kazuyuki Minowa, Kohsuke Kudo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The aquaporin-4 (AQP4) water channel is essential in neurofluid dynamics. AQP4 loss impairs solute exchange between the cerebrospinal fluid (CSF) and interstitial fluid (ISF). However, whether AQP4 expression affects solute clearance from th
Externí odkaz:
https://doaj.org/article/e73bbbf27a75479ab52ad1b58a25589a
Autor:
Sasagu Kurozumi, Kyoichi Kaira, Hiroshi Matsumoto, Masafumi Kurosumi, Takehiko Yokobori, Yoshikatsu Kanai, Chikako Sekine, Chikako Honda, Ayaka Katayama, Mio Furuya, Sho Shiino, Takaya Makiguchi, Nigel P. Mongan, Emad A. Rakha, Tetsunari Oyama, Takaaki Fujii, Ken Shirabe, Jun Horiguchi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract L-type amino acid transporter 1 (LAT1), also referred to as SLC7A5, is believed to regulate tumor metabolism and be associated with tumor proliferation. In invasive breast cancer, we clinicopathologically investigated the utility of LAT1 exp
Externí odkaz:
https://doaj.org/article/4daa3a3afb8940298b1d057e671dbd12
Autor:
Takaaki Fujii, Yuko Nakazawa, Misato Ogino, Sayaka Obayashi, Reina Yajima, Chikako Honda, Hideharu Nakamura, Takaya Makiguchi, Ken Shirabe
Publikováno v:
World Journal of Surgical Oncology, Vol 19, Iss 1, Pp 1-7 (2021)
Abstract Background Immediate breast reconstruction with skin-sparing (SSM) or nipple-sparing mastectomy (NSM) has become a common procedure. In this study, we evaluated the distance between breast tumor and skin in a series of patients undergoing IB
Externí odkaz:
https://doaj.org/article/6de05b862052490dafc9c33f4c0376ea
Publikováno v:
In Vivo; Jul/Aug2024, Vol. 38 Issue 4, p1935-1938, 4p
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Short-term synaptic plasticity is a fast and robust modification in neuronal presynaptic output that can enhance release strength to drive facilitation or diminish it to promote depression. The mechanisms that determine whether neurons displ
Externí odkaz:
https://doaj.org/article/0169aea43b4549faa17ab3ee1c7c007e
Autor:
Keiko Yanai, Takaaki Fujii, Jun Horiguchi, Yuko Nakazawa, Sasagu Kurozumi, Sayaka Obayashi, Reina Yajima, Ken Shirabe
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background S-1 and cyclophosphamide (CPA) can be given orally, and their combination may have great potential for treating metastatic breast cancer (MBC). A phase I study of sequential S-1 and CPA therapy was conducted in patients with MBC;
Externí odkaz:
https://doaj.org/article/e3ff1f9d18734ada96a5ca6baee57be1
Autor:
Sasagu Kurozumi, Mansour Alsaleem, Cíntia J. Monteiro, Kartikeya Bhardwaj, Stacey E. P. Joosten, Takaaki Fujii, Ken Shirabe, Andrew R. Green, Ian O. Ellis, Emad A. Rakha, Nigel P. Mongan, David M. Heery, Wilbert Zwart, Steffi Oesterreich, Simon J. Johnston
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-11 (2020)
Abstract Background Invasive lobular carcinoma (ILC) accounts for 10–15% of primary breast cancers and is typically estrogen receptor alpha positive (ER+) and ERBB2 non-amplified. Somatic mutations in ERBB2/3 are emerging as a tractable mechanism u
Externí odkaz:
https://doaj.org/article/d4597b94e0d64f6d896b2a13a644a68c
Autor:
Hiroko Toda, Naohiko Seki, Sasagu Kurozumi, Yoshiaki Shinden, Yasutaka Yamada, Nijiro Nohata, Shogo Moriya, Tetsuya Idichi, Kosei Maemura, Takaaki Fujii, Jun Horiguchi, Yuko Kijima, Shoji Natsugoe
Publikováno v:
Molecular Oncology, Vol 14, Iss 2, Pp 426-446 (2020)
Aberrantly expressed microRNA (miRNA) are known to disrupt intracellular RNA networks in cancer cells. Exploring miRNA‐dependent molecular networks is a major challenge in cancer research. In this study, we performed RNA‐sequencing of breast canc
Externí odkaz:
https://doaj.org/article/992e6c16aa6044f88fc160dae4633968
Autor:
Chikako Kanno Honda, Sasagu Kurozumi, Takaaki Fujii, Pourquier, Didier, Khellaf, Lakhdar, Boissiere, Florence, Jun Horiguchi, Tetsunari Oyama, Ken Shirabe, Colinge, Jacques, Takehiko Yokobori, Turtoi, Andrei
Publikováno v:
Theranostics; 2024, Vol. 14 Issue 5, p1873-1885, 13p
Autor:
Mami, Kikuchi, Takaaki, Fujii, Chikako, Honda, Keiko, Tanabe, Yuko, Nakazawa, Misato, Ogino, Sayaka, Obayashi, Ken, Shirabe
Publikováno v:
Anticancer Research. 43:217-221
Despite advances in the treatment of breast cancer, metastatic breast cancer (MBC) remains difficult to cure, and few MBC patients survive 10 years after receiving a breast cancer metastasis diagnosis. We collected the cases of patients with MBC who