Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Taka-aki Takeda"'
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 10, p 2179 (2017)
More than one-third of newly synthesized proteins are targeted to the early secretory pathway, which is comprised of the endoplasmic reticulum (ER), Golgi apparatus, and other intermediate compartments. The early secretory pathway plays a key role in
Externí odkaz:
https://doaj.org/article/b9a936fbf86540a48cc8f546cd073a27
Autor:
Yukina Nishito, Kathryn Mary Taylor, Naoya Kubo, Tokuji Tsuji, Yu-ki Tanaka, Sachiko Ueda, Eisuke Suzuki, Yasumitsu Ogra, Mayu Matsunaga, Tomohiro Yamazaki, Taka-aki Takeda, Ayako Fukunaka, Taiho Kambe, Namino Ogawa, Takashi Fujiwara
Publikováno v:
J Biol Chem
Numerous zinc ectoenzymes are metalated by zinc and activated in the compartments of the early secretory pathway before reaching their destination. Zn transporter (ZNT) proteins located in these compartments are essential for ectoenzyme activation. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fb8beda46493f1a12bfe36d136aff9
https://doi.org/10.1074/jbc.ra120.012610
https://doi.org/10.1074/jbc.ra120.012610
Autor:
Daniel Lea, Tamami Matsushita, Masasuke Araki, Shigeru Taketani, Lars N. Royall, Taka-aki Takeda
Publikováno v:
Brain Research. 1675:51-60
Iris neural stem/progenitor cells from mature porcine eyes were investigated using a new protocol for tissue culture, which consists of dispase treatment and Matrigel embedding. We used a number of culture conditions and found an intense differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ebc6c0bab95902bfccc1360e504888
https://doi.org/10.1016/j.brainres.2017.08.027
https://doi.org/10.1016/j.brainres.2017.08.027
Autor:
Yuka Adachi, Jun-ichi Fujisawa, Shingo Izawa, Taka-aki Takeda, Keiko Ohnishi, Machiko Sasai, Shigeru Taketani
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1861:1813-1824
Background The degradation of heme significantly contributes to cytoprotective effects against oxidative stress and inflammation. The enzyme heme oxygenase-1 (HO-1), involved in the degradation of heme, forms carbon monoxide (CO), ferrous iron, and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a23dc3d3b717c4ce3f2dd3876a1335
https://doi.org/10.1016/j.bbagen.2017.03.018
https://doi.org/10.1016/j.bbagen.2017.03.018
Autor:
Kazuhisa Fukue, Toshiyuki Fukada, Taka-aki Takeda, Takafumi Hara, Teruhisa Takagishi, Taiho Kambe
Publikováno v:
The Journal of Physiological Sciences. 67:283-301
Zinc (Zn) is an essential trace mineral that regulates the expression and activation of biological molecules such as transcription factors, enzymes, adapters, channels, and growth factors, along with their receptors. Zn deficiency or excessive Zn abs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260071d81052db78505e2b83bd2978dc
https://doi.org/10.1007/s12576-017-0521-4
https://doi.org/10.1007/s12576-017-0521-4
Autor:
Israel Sekler, Yusaku Miyamae, Masaya Nagao, Eitan Hoch, Kazuhisa Fukue, Tokuji Tsuji, Dax Fu, Ayako Fukunaka, Taiho Kambe, Seiji Masuda, Taka-aki Takeda, Takashi Fujiwara, Chengfeng Merriman, Yukina Nishito, Shigeyuki Fujimoto
Publikováno v:
Biochemical Journal. 473:2611-2621
Secretory and membrane-bound zinc-requiring enzymes are thought to be activated by binding zinc in the early secretory pathway. One such enzyme, tissue-non-specific alkaline phosphatase (TNAP), is activated through a two-step mechanism, via protein s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d7f2de1041fb43fbda1ec78032375a
https://doi.org/10.1042/bcj20160324
https://doi.org/10.1042/bcj20160324
Autor:
Ayu Matsunaga, Yukina Nishito, Seiichiro Himeno, Satoshi Kono, Hiroshi Narita, Fumie Teranishi, Tomohiro Yamazaki, Fumiko Okazaki, Rajini Rao, Natsuko Tsuji, Hitomi Fujishiro, Taiho Kambe, Taka Aki Takeda, Hiroaki Miyajima, Karin Tuschl
Publikováno v:
Journal of Biological Chemistry. 291:14773-14787
Manganese homeostasis involves coordinated regulation of specific proteins involved in manganese influx and efflux. However, the proteins that are involved in detoxification/efflux have not been completely resolved nor has the basis by which they sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0150c1343cf6bc0cce59ea7b98598881
https://doi.org/10.1074/jbc.m116.728014
https://doi.org/10.1074/jbc.m116.728014
Autor:
Tatsuyoshi Kawamura, Hitoshi Shirakawa, Katsutoshi Nishino, Minami Ooi, Fumito Tani, Taka Aki Takeda, Miki U. Kobayashi, Tomoko Goto, Shiho Miyazaki, Michio Komai, Mayu Matsunaga, Taiho Kambe
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-13 (2018)
Zinc deficiency causes myriad pathophysiological symptoms, but why distinct phenotypes are generated by zinc deficiency remains unclear. Considering that several ectoenzymes involved in purinergic signaling through extracellular adenine-nucleotide hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6ac3f489ec9914c98d960f2f9f5078
http://hdl.handle.net/2433/244792
http://hdl.handle.net/2433/244792
Publikováno v:
Archives of biochemistry and biophysics. 611
In humans, about 1000 enzymes are estimated to bind zinc. In most of these enzymes, zinc is present at the active site; thus, these enzymes are functional as "zinc-requiring enzymes". Of these zinc-requiring enzymes, zinc-requiring ectoenzymes (defin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9838383027aff4d9463139344a4af1
https://pubmed.ncbi.nlm.nih.gov/27046342
https://pubmed.ncbi.nlm.nih.gov/27046342
Publikováno v:
Scientific Reports
It is well known that haem serves as the prosthetic group of various haemoproteins that function in oxygen transport, respiratory chain and drug metabolism. However, much less is known about the functions of the catabolites of haem in mammalian cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05fef0fba3c28d9d3a8bcf3360a75df
https://doi.org/10.1038/srep10488
https://doi.org/10.1038/srep10488