Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Taka-aki Okabe"'
Publikováno v:
International Journal of Cardiology. 167:140-145
Aims We tested the hypothesis that immunoglobulin ameliorated experimental autoimmune myocarditis (EAM) in mice attributing to the suppression of reactive oxygen species (ROS)-mediated myocardial injury. Methods We intraperitoneally administered inta
Publikováno v:
Journal of Cardiovascular Pharmacology. 52:445-451
Little is known about effects of naloxone, an opiate receptor antagonist, upon experimental autoimmune myocarditis (EAM) in mice. The aim of the present study was to test the effects of naloxone upon EAM in mice. Four-week-old C57BL/6 mice were injec
Publikováno v:
International Journal of Experimental Pathology. 89:382-388
Myocarditis is caused by many agents, such as viruses, bacteria and drugs (Liu & Masun 2001). The disease is characterized by acute and chronic phases. In humans, acute myocarditis is a potentially lethal disease and precedes the development of cardi
Autor:
Koji Hasegawa, Toru Kita, Masaomi Nimata, Chiharu Kishimoto, Zuyi Yuan, Taka-aki Okabe, Keisuke Shioji
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 289:H1147-H1152
Some ANG II receptor type 1 (AT1) antagonists are reported to inhibit proinflammatory cytokine production in vitro and in vivo. However, the effects of the drugs on autoimmune diseases are unknown. We tested the hypothesis that olmesartan, a novel AT
Autor:
Toshinori Murayama, Kana Shimada, Masayuki Yokode, Toru Kita, Taka-aki Okabe, Chiharu Kishimoto
Publikováno v:
Circulation Journal. 69:1543-1546
Background Although immunoglobulin treatment, beginning simultaneously with the initiation of atherosclerosis, suppresses experimental atherosclerosis in apolipoprotein E-deficient mice, it remains unclear whether the treatment at a subsequent stage
Publikováno v:
Journal of molecular and cellular cardiology. 49(3)
We systematically investigated serial efficacy of granulocyte colony-stimulating factor (G-CSF) therapy upon experimental autoimmune myocarditis (EAM) in rats treated with and without the inhibition of nitric oxide (NO) with the analyses of tissue re
Publikováno v:
International journal of experimental pathology. 89(5)
It was previously shown that administration of the nitric oxide synthase inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME) aggravated murine viral myocarditis by increasing myocardial virus titres. Experimental autoimmune myocarditis in mice and
Publikováno v:
Experimental and clinical cardiology. 11(4)
It has already been shown that mild to moderate exercise training may protect against the development of atherosclerosis. However, the precise mechanisms behind this protection are still unknown. The hypothesis that exercise training reduces the seve
Autor:
Taka-aki Okabe, Kana Shimada, Toru Kita, Masayuki Yokode, Miki Hattori, Chiharu Kishimoto, Toshinori Murayama
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 71(7)
Background Exercise training may protect against the development of atherosclerosis, although the precise mechanisms are still unknown. The present study assessed the hypothesis that exercise training would reduce the severity of experimental atheros
Autor:
Kana Shimada, Chiharu Kishimoto, Miki Hattori, Toru Kita, Taka-aki Okabe, Toshinori Murayama, Masayuki Yokode
Publikováno v:
Cardiovascular research. 74(3)
Objective : It was shown that aerobic exercise training may protect against the development of atherosclerosis. However, the precise mechanisms are still unknown. We assessed the hypothesis that exercise training reduced the severity of experimental