Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tak Mak"'
Autor:
Wing Lam, Kenny Dang, Cheuk Him Man, Xiao-Yuan Zeng, Lichuan Zheng, Nelson Ka-Lam Ng, Koon-Chuen Chan, Tsz-Ho Kwok, Timothy Chi-Chun Ng, Wing-Yan Leung, Michael Shing-Yan Huen, Carmen Chak-Lui Wong, Chi Wai Eric So, Zhixun Dou, Mark Robert Bray, Tak Mak, Anskar Yh Leung
Publikováno v:
HemaSphere, Vol 7, p e87320b0 (2023)
Externí odkaz:
https://doaj.org/article/95133beb511645219651e7d654e2337c
Autor:
Océane C.B. Martin, Anna Bergonzini, Maria Lopez Chiloeches, Eleni Paparouna, Deborah Butter, Sofia D.P. Theodorou, Maria M. Haykal, Elisa Boutet-Robinet, Toma Tebaldi, Andrew Wakeham, Mikael Rhen, Vassilis G. Gorgoulis, Tak Mak, Ioannis S. Pateras, Teresa Frisan
Publikováno v:
Cell Reports, Vol 35, Iss 1, Pp 108931- (2021)
Summary: Bacterial genotoxins cause DNA damage in eukaryotic cells, resulting in activation of the DNA damage response (DDR) in vitro. These toxins are produced by Gram-negative bacteria, enriched in the microbiota of inflammatory bowel disease (IBD)
Externí odkaz:
https://doaj.org/article/09013ccda2564c55996c3bde6c4f4f7d
Autor:
Ying-Ju Chang, Lily Zhou, Richard Binari, Armen Manoukian, Tak Mak, Helen McNeill, Vuk Stambolic
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252252 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0152259.].
Externí odkaz:
https://doaj.org/article/5815747e49c44f1a80a568ff94fea182
Autor:
Luis Palomero, Ivan Galván-Femenía, Rafael de Cid, Roderic Espín, Daniel R. Barnes, CIMBA, Eline Blommaert, Miguel Gil-Gil, Catalina Falo, Agostina Stradella, Dan Ouchi, Albert Roso-Llorach, Concepció Violan, María Peña-Chilet, Joaquín Dopazo, Ana Isabel Extremera, Mar García-Valero, Carmen Herranz, Francesca Mateo, Elisabetta Mereu, Jonathan Beesley, Georgia Chenevix-Trench, Cecilia Roux, Tak Mak, Joan Brunet, Razq Hakem, Chiara Gorrini, Antonis C. Antoniou, Conxi Lázaro, Miquel Angel Pujana
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101296- (2020)
Summary: Proper immune system function hinders cancer development, but little is known about whether genetic variants linked to cancer risk alter immune cells. Here, we report 57 cancer risk loci associated with differences in immune and/or stromal c
Externí odkaz:
https://doaj.org/article/48b5448d3f914e5b93d5435b360411fd
Autor:
Nisha Kanwar, Katia Carmine-Simmen, Ranju Nair, Chunjie Wang, Soode Moghadas-Jafari, Heiko Blaser, Danh Tran-Thanh, Dongyu Wang, Peiqi Wang, Jenny Wang, Adrian Pasculescu, Alessandro Datti, Tak Mak, John D. Lewis, Susan J. Done
Publikováno v:
EBioMedicine, Vol 52, Iss , Pp - (2020)
Background: Previously, we found that amplification of chromosome 17q24.1-24.2 is associated with lymph node metastasis, tumour size, and lymphovascular invasion in invasive ductal carcinoma. A gene within this amplicon, CACNG4, an L-type voltage-gat
Externí odkaz:
https://doaj.org/article/bcf2fd8c92ec438eb03e56d62e88cb82
Autor:
Tak Mak
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 675-679 (2016)
Abstract Real innovations in medicine and science are historic and singular; the stories behind each occurrence are precious. At Molecular Medicine we have established the Anthony Cerami Award in Translational Medicine to document and preserve these
Externí odkaz:
https://doaj.org/article/e0b0c69e6ba9432c8463f72b6b8a084e
Autor:
Ying-Ju Chang, Lily Zhou, Richard Binari, Armen Manoukian, Tak Mak, Helen McNeill, Vuk Stambolic
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152259 (2016)
The insulin/IGF-1 signaling pathway mediates various physiological processes associated with human health. Components of this pathway are highly conserved throughout eukaryotic evolution. In Drosophila, the PTEN ortholog and its mammalian counterpart
Externí odkaz:
https://doaj.org/article/e92396b3a24f482aa660954c8987946b
Autor:
Ying-Ju Chang, Scott Pownall, Thomas E Jensen, Samar Mouaaz, Warren Foltz, Lily Zhou, Nicole Liadis, Minna Woo, Zhenyue Hao, Previn Dutt, Philip J Bilan, Amira Klip, Tak Mak, Vuk Stambolic
Publikováno v:
eLife, Vol 4 (2015)
Adipose tissue is crucial for the maintenance of energy and metabolic homeostasis and its deregulation can lead to obesity and type II diabetes (T2D). Using gene disruption in the mouse, we discovered a function for a RhoA-specific guanine nucleotide
Externí odkaz:
https://doaj.org/article/88d9c968a27b4031b4373750c5e2dd80
Autor:
Connor Yanchus, Kristen L. Drucker, Thomas M. Kollmeyer, Ricky Tsai, Warren Winick-Ng, Minggao Liang, Ahmad Malik, Judy Pawling, Silvana B. De Lorenzo, Asma Ali, Paul A. Decker, Matt L. Kosel, Arijit Panda, Khalid N. Al-Zahrani, Lingyan Jiang, Jared W. L. Browning, Chris Lowden, Michael Geuenich, J. Javier Hernandez, Jessica T. Gosio, Musaddeque Ahmed, Sampath Kumar Loganathan, Jacob Berman, Daniel Trcka, Kulandaimanuvel Antony Michealraj, Jerome Fortin, Brittany Carson, Ethan W. Hollingsworth, Sandra Jacinto, Parisa Mazrooei, Lily Zhou, Andrew Elia, Mathieu Lupien, Housheng Hansen He, Daniel J. Murphy, Liguo Wang, Alexej Abyzov, James W. Dennis, Philipp G. Maass, Kieran Campbell, Michael D. Wilson, Daniel H. Lachance, Margaret Wrensch, John Wiencke, Tak Mak, Len A. Pennacchio, Diane E. Dickel, Axel Visel, Jeffrey Wrana, Michael D. Taylor, Gelareh Zadeh, Peter Dirks, Jeanette E. Eckel-Passow, Liliana Attisano, Ana Pombo, Cristiane M. Ida, Evgeny Z. Kvon, Robert B. Jenkins, Daniel Schramek
Publikováno v:
Science
Establishing causal links between inherited polymorphisms and cancer risk is challenging. Here, we focus on the single-nucleotide polymorphism rs55705857, which confers a sixfold greater risk of isocitrate dehydrogenase ( IDH) –mutant low-grade gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0962bd008ed19485d953421b33939b
https://doi.org/10.1126/science.abj2890
https://doi.org/10.1126/science.abj2890
Autor:
Connor Yanchus, Kristen L. Drucker, Thomas M. Kollmeyer, Ricky Tsai, Minggao Liang, Lingyan Jiang, Judy Pawling, Asma Ali, Paul Decker, Matt Kosel, Arijit Panda, Ahmad Malik, Khalid N. Al-Zahrani, J. Javier Hernandez, Musaddeque Ahmed, Sampath Kumar Loganathan, Daniel Trcka, Antony Michaelraj, Jerome Fortin, Parisa Mazrooei, Lily Zhou, Andrew Elia, Mathieu Lupien, Housheng Hansen He, Liguo Wang, Alexej Abyzov, James W. Dennis, Michael D. Wilson, Jeffrey Wrana, Daniel Lachance, Margaret Wrensch, John Wiencke, Len A. Pennacchio, Diane E. Dickel, Axel Visel, Michael Taylor, Gelareh Zadeh, Peter Dirks, Jeanette E. Eckel-Passow, Tak Mak, Evgeny Kvon, Robert B. Jenkins, Daniel Schramek
Establishing causal links between inherited polymorphisms and cancer risk is challenging. Here, we focus on the single nucleotide polymorphism rs55705857 (A>G), which confers a 6-fold increased risk of IDH-mutant low-grade glioma (LGG) and is amongst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::180fd8f9c159efa7af618e701ec0e230
https://doi.org/10.1101/2022.03.08.22272044
https://doi.org/10.1101/2022.03.08.22272044
