Zobrazeno 1 - 10
of 470
pro vyhledávání: '"Tak Hang Chan"'
Autor:
Sze Wan Hung, Massimiliano Gaetani, Yiran Li, Zhouyurong Tan, Xu Zheng, Ruizhe Zhang, Yang Ding, Gene Chi Wai Man, Tao Zhang, Yi Song, Yao Wang, Jacqueline Pui Wah Chung, Tak Hang Chan, Roman A. Zubarev, Chi Chiu Wang
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 1, Pp 100-114 (2024)
Endometriosis is a common chronic gynecological disease with endometrial cell implantation outside the uterus. Angiogenesis is a major pathophysiology in endometriosis. Our previous studies have demonstrated that the prodrug of epigallocatechin galla
Externí odkaz:
https://doaj.org/article/a7cafd993de04625a91fc892b7425898
Autor:
Kai On Chu, Gene Chi Wai Man, Sze Wan Hung, Tak Hang Chan, Wai Yip Thomas Lee, Kwok Ping Chan, Chi Pui Pang, Chi Chiu Wang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Graphical Abstract
Externí odkaz:
https://doaj.org/article/e1457322e18145f2bf951601e4067ee8
Autor:
Gene Chi Wai Man, Jianzhang Wang, Yi Song, Jack Ho Wong, Yu Zhao, Tat San Lau, Kam Tong Leung, Tak Hang Chan, Huating Wang, Joseph Kwong, Tzi Bun Ng, Chi Chiu Wang
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Previous studies have shown a major green tea polyphenol (−)-epigallocatechin-3-gallate ((−)-EGCG) as a powerful anti-cancer agent. However, its poor bioavailability and requirement of a high dosage to manifest activity have r
Externí odkaz:
https://doaj.org/article/a7f334cec11049b0b24c5bf84175489e
Autor:
Sze Wan Hung, Bo Liang, Yating Gao, Ruizhe Zhang, Zhouyurong Tan, Tao Zhang, Pui Wah Jacqueline Chung, Tak Hang Chan, Chi Chiu Wang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Endometriosis is defined as endometrial tissues found outside the uterine cavity. ProEGCG is a prodrug of Epigallocatechin gallate (EGCG), a potent polyphenol found in green tea. It inhibits the development of endometriotic lesions of mouse model in
Externí odkaz:
https://doaj.org/article/f71b4a89bd1548f28d83c9a39ccd3dab
Autor:
Kin-Fai Chan, Ning Sun, Siu-Cheong Yan, Iris L. K. Wong, Hok-Kiu Lui, Kwan-Choi Cheung, Jian Yuan, Fung-Yi Chan, Zhiwei Zheng, Edward W. C. Chan, Sheng Chen, Yun-Chung Leung, Tak Hang Chan, Kwok-Yin Wong
Publikováno v:
ACS Omega, Vol 2, Iss 10, Pp 7281-7292 (2017)
Externí odkaz:
https://doaj.org/article/fe43b9ffa0e742c497654357194e1226
Autor:
Larry M.C. Chow, Tak-Hang Chan, Xiaochun Su, Wenqin Sun, Xinqing Yang, Iris L.K. Wong, Tsun Sing Chow, Kit-Ying Choy, Teng Chen, Yunjiao He, Peng Li
Figures S1 to S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01564b7f39b9c1e196ce5429dacdf466
https://doi.org/10.1158/1535-7163.22521109.v1
https://doi.org/10.1158/1535-7163.22521109.v1
Autor:
Larry M.C. Chow, Tak Hang Chan
Publikováno v:
Canadian Journal of Chemistry. 100:85-97
Multidrug resistance (MDR) is often a major impediment to successful chemotherapy in the treatment of cancer. A common mechanism for MDR is the overexpression of an active ATP-binding cassette (ABC) transporter protein, P-glycoprotein (P-gp/ABCB1, al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::471c4ca8f48d615c4d91e127fc8f77d2
https://doi.org/10.1139/cjc-2021-0108
https://doi.org/10.1139/cjc-2021-0108
Autor:
Wenqin Sun, Iris L. K. Wong, Helen Ka-Wai Law, Xiaochun Su, Terry C. F. Chan, Gege Sun, Xinqing Yang, Xingkai Wang, Tak Hang Chan, Shengbiao Wan, Larry M. C. Chow
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4377
Volume 24
Issue 5
Pages: 4377
The modulation of P-glycoprotein (P-gp, ABCB1) can reverse multidrug resistance (MDR) and potentiate the efficacy of anticancer drugs. Tea polyphenols, such as epigallocatechin gallate (EGCG), have low P-gp-modulating activity, with an EC50 over 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f66d38295de12b95ead2a18b4c76ef