Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Tajie H. Harris"'
Autor:
Ashley R. Ricciardelli, Ariadna Robledo, Jason E. Fish, Peter T. Kan, Tajie H. Harris, Joshua D. Wythe
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2876 (2023)
Brain arteriovenous malformations (bAVMs) are focal vascular lesions composed of abnormal vascular channels without an intervening capillary network. As a result, high-pressure arterial blood shunts directly into the venous outflow system. These high
Externí odkaz:
https://doaj.org/article/5985cf6a8cae4f38adf4124f37d75884
Autor:
Samantha J. Batista, Katherine M. Still, David Johanson, Jeremy A. Thompson, Carleigh A. OʼBrien, John R. Lukens, Tajie H. Harris
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Control over T. gondii infection in the brain involves microglial cells, but how these cells execute this control is not clear. Here the authors show that unlike IL-1β dominant macrophages, microglia are primed for gasdermin-D-dependent IL-1α produ
Externí odkaz:
https://doaj.org/article/3dcd849f496a440e86d76c688c091fee
Autor:
Shinya Hidano, Louise M. Randall, Lucas Dawson, Hans K. Dietrich, Christoph Konradt, Peter J. Klover, Beena John, Tajie H. Harris, Qun Fang, Bradley Turek, Takashi Kobayashi, Lothar Hennighausen, Daniel P. Beiting, Anita A. Koshy, Christopher A. Hunter
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT The local production of gamma interferon (IFN-γ) is important to control Toxoplasma gondii in the brain, but the basis for these protective effects is not fully understood. The studies presented here reveal that the ability of IFN-γ to inh
Externí odkaz:
https://doaj.org/article/b1805e78fdca4cabb73b13758748f715
Autor:
Lindsey A Shallberg, Anthony T Phan, David A Christian, Joseph A Perry, Breanne E Haskins, Daniel P Beiting, Tajie H Harris, Anita A Koshy, Christopher A Hunter
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010296 (2022)
Initial TCR engagement (priming) of naive CD8+ T cells results in T cell expansion, and these early events influence the generation of diverse effector and memory populations. During infection, activated T cells can re-encounter cognate antigen, but
Externí odkaz:
https://doaj.org/article/e36f4bc3486d41dcb1fa8011ac3cf398
Autor:
Michael A Kovacs, Maureen N Cowan, Isaac W Babcock, Lydia A Sibley, Katherine Still, Samantha J Batista, Sydney A Labuzan, Ish Sethi, Tajie H Harris
Publikováno v:
eLife. 11
The discovery of meningeal lymphatic vessels that drain the CNS has prompted new insights into how immune responses develop in the brain. In this study, we examined how T cell responses against CNS-derived antigen develop in the context of infection.
Autor:
Michael A Kovacs, Maureen N Cowan, Isaac W Babcock, Lydia A Sibley, Katherine Still, Samantha J Batista, Sydney A Labuzan, Ish Sethi, Tajie H Harris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe86b45fed3a64113e3dadfb938ec33e
https://doi.org/10.7554/elife.80775.sa2
https://doi.org/10.7554/elife.80775.sa2
Autor:
Tajie H. Harris, Breanna R. Noffsinger, Natasha D. Sheybani, Aizhen Xiao, Alexandra R. Witter, Laryssa Manigat, Timothy N. J. Bullock, Suchet Taori, Richard J. Price, Qing Zhong, Benjamin Purow
Publikováno v:
J Neurooncol
PURPOSE: Due to the recent rise in immunotherapy research to treat glioblastoma (GBM), immunocompetent mouse models have become increasingly crucial. However, the character and kinetics of the immune response against the most prevalent immunocompeten
Autor:
Michael A. Kovacs, Maureen N. Cowan, Isaac W. Babcock, Lydia A. Sibley, Katherine Still, Samantha J. Batista, Sydney A. Labuzan, Ish Sethi, Tajie H. Harris
The discovery of meningeal lymphatic vessels that drain the central nervous system (CNS) has prompted new insights into how neuroinflammation develops. In this study, we examined how T cell responses against CNS-derived antigen develop in the context
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b246830831e62b4b9b3986c35632fb1
https://doi.org/10.1101/2022.06.02.494581
https://doi.org/10.1101/2022.06.02.494581
Autor:
Maureen N. Cowan, Michael A. Kovacs, Ish Sethi, Isaac W. Babcock, Katherine Still, Samantha J. Batista, Carleigh A. O’Brien, Jeremy A. Thompson, Lydia A. Sibley, Sydney A. Labuzan, Tajie H. Harris
Publikováno v:
PLoS pathogens. 18(9)
Toxoplasma gondiiis a ubiquitous intracellular protozoan parasite that establishes a life-long chronic infection largely restricted to the central nervous system (CNS). Constant immune pressure, notably IFN-γ-STAT1 signaling, is required for prevent
Autor:
Lindsey A Shallberg, Anthony T Phan, David A Christian, Joseph A Perry, Breanne E Haskins, Daniel P Beiting, Tajie H Harris, Anita A Koshy, Christopher A Hunter
Initial TCR engagement of CD8+T cells results in T cell expansion, and these early events influence the generation of diverse effector and memory populations. During infection, some activated T cells re-encounter cognate antigen, but how these events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a99f45c26207e021752dccf1ab35498d
https://doi.org/10.1101/2022.01.25.477653
https://doi.org/10.1101/2022.01.25.477653