Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tajalli Ilm Chandel"'
Autor:
Syed Mohammad Zakariya, Rizwan Hasan Khan, Maroof Ali, Mariyam Afghani, Ibrar Siddique, Aiman Masroor, Tajalli Ilm Chandel
Publikováno v:
International Journal of Biological Macromolecules. 154:1448-1459
This study is based on the analysis of the recent trend of medication in neurodegenerative diseases. Due to the asymptomatic nature of the diseases, medication delays. Therefore, mechanism of medication assists in removal of the symptoms. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed17fc9b554157395c40742448b443c3
https://doi.org/10.1016/j.ijbiomac.2019.11.026
https://doi.org/10.1016/j.ijbiomac.2019.11.026
Publikováno v:
ACS Chemical Neuroscience. 11:373-384
Increasing prevalence of protein misfolding disorders urges the search for effective therapies. Although several antiaggregation molecules have been identified, their molecular process of aggregation and clinical trials are underway. The present stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd03069757c82b912734f32779df8050
https://doi.org/10.1021/acschemneuro.9b00593
https://doi.org/10.1021/acschemneuro.9b00593
Autor:
Ibrar Siddique, Ishrat Jahan, Vladimir N. Uversky, Aiman Masroor, Maroof Ali, Nida Zaidi, Shahid M. Nayeem, Masihuz Zaman, Rizwan Hasan Khan, Tajalli Ilm Chandel
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1867:275-285
Protein aggregation have been associated with several human neurodegenerative diseases, such as Parkinson's and Alzheimer's diseases. There are several small molecules that can reduce aggregation of proteins. The present study aimed to test the hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2731f5231b17245d92b6ac21fbbef0
https://doi.org/10.1016/j.bbapap.2018.10.003
https://doi.org/10.1016/j.bbapap.2018.10.003
Autor:
Rizwan Hasan Khan, Aiman Masroor, Ishrat Jahan, Maroof Ali, Ibrar Siddique, Mohammad Khursheed Siddiqi, Tajalli Ilm Chandel, Shahid M. Nayeem, Vladimir N. Uversky
Publikováno v:
Journal of Molecular Liquids. 278:553-567
This study summarises the results of multifactorial analysis of the inhibition/destabilization of human serum albumin (HSA) amyloid fibrils by an anti-Parkinson's drug, benserazide hydrochloride (BH). Different biophysical techniques have been utiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18b31a17179cacd8c5a279486ce0f201
https://doi.org/10.1016/j.molliq.2018.12.127
https://doi.org/10.1016/j.molliq.2018.12.127
Autor:
Maroof Ali, Mohsin Vahid Khan, Mohd Ishtikhar, Masihuz Zaman, Gulam Rabbani, Tajalli Ilm Chandel, Rizwan Hasan Khan
Publikováno v:
International Journal of Biological Macromolecules. 106:1115-1129
This review article summarises the possible mechanisms of the protein-ligand interaction, folding, misfolding, aggregation and inhibition of protein aggregates. Under certain stressed condition the folding process deviates from its path and results i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746ab6adc354cf003bf281ab8e89e30b
https://doi.org/10.1016/j.ijbiomac.2017.07.185
https://doi.org/10.1016/j.ijbiomac.2017.07.185
Autor:
Masihuz Zaman, Syed Mohammad Zakariya, Parvez Alam, Mohammad Ajmal, Saima Nusrat, Syed M. Meeran, Wahiduzzaman, Rizwan Hasan Khan, Tajalli Ilm Chandel
Publikováno v:
International Journal of Biological Macromolecules. 105:556-565
Protein aggregation and misfolding have been allied with numerous human disorders and thus inhibition of such occurrence has been center for intense research efforts against these diseases. Here, we investigated anti-fibrillation activity of cysteine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd306cd56212ef107587739ff4c9ab69
https://doi.org/10.1016/j.ijbiomac.2017.07.083
https://doi.org/10.1016/j.ijbiomac.2017.07.083
Autor:
Rizwan Hasan Khan, Vladimir N. Uversky, Tajalli Ilm Chandel, Sadia Malik, Qazi Noorul Mateen, Aiman Masroor
Publikováno v:
Archives of Biochemistry and Biophysics. 709:108981
Screening of inhibitors that slow down or suppress amyloid fibrils formation relies on some simple but sensitive spectroscopy techniques. Thioflavin T (ThT) fluorescence assay is one of the most common, amyloid specific and sensitive method. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d016e51b91742e3d8438e8044b69296e
https://doi.org/10.1016/j.abb.2021.108981
https://doi.org/10.1016/j.abb.2021.108981
Autor:
Masihuz Zaman, Ali S. Abdelhameed, Mohsin Vahid Khan, Mohammad Khursheed Siddiqui, Tajalli Ilm Chandel, Rizwan Hasan Khan, Mohd Rehan Ajmal
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 36:2543-2557
Protein aggregation into oligomers and mature fibrils are associated with more than 20 diseases in humans. The interactions between cationic surfactants dodecyltrimethylammonium bromide (DTAB) and tetradecyltrimethylammonium bromide (TTAB) with varyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a78d49e3ffc2487b15cf1f675330974
https://doi.org/10.1080/07391102.2017.1363085
https://doi.org/10.1080/07391102.2017.1363085
Autor:
Ali S. Abdelhameed, Masihuz Zaman, Mohd Rehan Ajmal, Mohammad Khursheed Siddiqui, Yasser E. Shahein, Rizwan Hasan Khan, Mohd Ishtikhar, Mohsin Vahid Khan, Nabeela Majid, Tajalli Ilm Chandel
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 36:1261-1273
The aggregation phenomenon (amyloid and amorphous) is associated with several pathological complications in human, such as Alzheimer's, Parkinson's, Huntington, Cataract diseases, and Diabetes mellitus type 2. In the present study we are offering evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a758f37645168239dce751915c9ca2
https://doi.org/10.1080/07391102.2017.1318718
https://doi.org/10.1080/07391102.2017.1318718
Publikováno v:
Indian Journal of Biochemistry & Biophysics; Jan2022, Vol. 59 Issue 1, p23-32, 10p