Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Taiyu Shen"'
Autor:
Yindi Xiong, Taiyu Shen, Peng Lou, Jingyue Yang, John P. Kastelic, Jingping Liu, Chuang Xu, Bo Han, Jian Gao
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Bovine mastitis is an infectious disease that causes substantial economic losses to the dairy industry worldwide. Current antibiotic therapy faces issues of antibiotic misuse and antimicrobial resistance, which has aroused concerns for both
Externí odkaz:
https://doaj.org/article/54f1115638504e278faffa01707cbf58
Autor:
Wanli Zhao, Taiyu Shen, Bichen Zhao, Moli Li, Zhaoju Deng, Yihui Huo, Ben Aernouts, Juan J. Loor, Androniki Psifidi, Chuang Xu
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Subacute ruminal acidosis (SARA) causes an increase in endotoxin, which can induce immune and inflammatory responses in the ruminal epithelium of dairy cows. In non-ruminants, epigallocatechin-3-gallate (EGCG), a major bioactive i
Externí odkaz:
https://doaj.org/article/9cfeb27fad3c4285978a0e933341833c
Autor:
Hao Yu, Minghe Fan, Xiying Chen, Xiuhuan Jiang, Juan J. Loor, Ahmad Aboragah, Cai Zhang, Hongxu Bai, Zhiyuan Fang, Taiyu Shen, Zhe Wang, Yuxiang Song, Xinwei Li, Guowen Liu, Xiaobing Li, Xiliang Du
Publikováno v:
Journal of Dairy Science, Vol 105, Iss 8, Pp 6997-7010 (2022)
ABSTRACT: Activated autophagy-lysosomal pathway (ALP) can degrade virtually all kinds of cellular components, including intracellular lipid droplets, especially during catabolic conditions. Sustained lipolysis and increased plasma fatty acids concent
Externí odkaz:
https://doaj.org/article/28de0d8ad64b49579b82beb0d899bd83
Autor:
Kaiming Yue, Xudong Pu, Juan J. Loor, Qianming Jiang, Jihong Dong, Taiyu Shen, Guojin Li, Wenwen Gao, Lin Lei, Xiliang Du, Yuxiang Song, Guowen Liu, Xinwei Li
Publikováno v:
Journal of Dairy Science, Vol 105, Iss 7, Pp 6030-6040 (2022)
ABSTRACT: When ketosis occurs, supraphysiological levels of free fatty acids (FFA) can cause oxidative injury to the mammary gland and autophagy can regulate the cellular oxidative status. The aim of this study was to investigate the autophagy status
Externí odkaz:
https://doaj.org/article/b2d95c4ddb9645b79a048f5faed308f8
Autor:
Xiliang Du, Chiara Di Malta, Zhiyuan Fang, Taiyu Shen, Xiaodi Niu, Meng Chen, Bo Jin, Hao Yu, Lin Lei, Wenwen Gao, Yuxiang Song, Zhe Wang, Chuang Xu, Zhijun Cao, Guowen Liu, Xinwei Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 6, Pp 2869-2886 (2022)
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis and insulin resistance and there are currently no approved drugs for its treatment. Hyperactivation of mTOR complex 1 (mTORC1) and subsequent impairment of the transcripti
Externí odkaz:
https://doaj.org/article/34596150e8264f92a01c724846c248f1
Autor:
Zhiyuan Fang, Xinwei Li, Shu Wang, Qianming Jiang, Juan J. Loor, Xiuhuan Jiang, Lingxue Ju, Hao Yu, Taiyu Shen, Men Chen, Yuxiang Song, Zhe Wang, Xiliang Du, Guowen Liu
Publikováno v:
Journal of Dairy Science, Vol 105, Iss 5, Pp 4520-4533 (2022)
ABSTRACT: Ketosis occurs most frequently in the peripartal period and is associated with liver injury and steatosis. Lysosomes serve as the terminal degradative station and contribute to liver homeostasis through their role in the digestion of dysfun
Externí odkaz:
https://doaj.org/article/3f6e8cc2991f448d9ae827b5e3eb6d0d
Autor:
Zhiyuan Fang, Yanyong Xu, Guowen Liu, Qi Shao, Xiaodi Niu, Wenjun Tai, Taiyu Shen, Minghe Fan, Meng Chen, Lin Lei, Wenwen Gao, Yuxiang Song, Zhe Wang, Xiliang Du, Xinwei Li
Acetaminophen (APAP) overdose is the predominant cause of drug-induced liver injury worldwide. The macroautophagy/autophagy-lysosomal pathway (ALP) is involved in the APAP hepatotoxicity. TFEB (transcription factor EB) promotes the expression of gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c7a6ad94ef65f98a454fbfb66f0dae
Autor:
Guowen Liu, Lingxue Ju, Zhe Wang, Xinwei Li, Meng Chen, Juan J. Loor, Ahmad Aboragah, Taiyu Shen, Zhiyuan Fang, Yiwei Zhu, Hao Yu, Hongsheng Ouyang, Yuxiang Song, Xiliang Du, Bo Jin
Publikováno v:
Journal of Dairy Science. 104:11973-11982
Free fatty acids (FFA)-induced hepatic inflammation agravates liver injury and metabolic dysfunction in dairy cows with ketosis or fatty liver. Under stressful conditions, autophagy is generally considered as a cell protection mechanism, but whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ca6293fab715c690abe713799a073f
https://doi.org/10.3168/jds.2021-20273
https://doi.org/10.3168/jds.2021-20273
Autor:
Xinghui Wang, Yiwei Zhu, Xinwei Li, Heyuan Wang, Guowen Liu, Zhicheng Peng, Zhiyuan Fang, Xiliang Du, Juan J. Loor, Guanghou Shui, Yuxiang Song, Meng Chen, Taiyu Shen, Zhe Wang, Zhen Shi
Publikováno v:
Br J Pharmacol
Background and purpose Identifying safe and effective compounds that target to mitophagy to eliminate impaired mitochondria may be an attractive therapeutic strategy for non-alcoholic fatty liver disease. Here, we investigated the effects of cyanidin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ddcd90ac1597d8e5a73a6b60c283ee
https://doi.org/10.1111/bph.15083
https://doi.org/10.1111/bph.15083
Publikováno v:
Journal of Dairy Research. 87:52-55
The experiments reported in this research communication aimed to compare the serum nonesterified fatty acid (NEFA) composition in ketotic cows and healthy cows during the perinatal period. NEFAs play significant roles in etiology and pathology of ket
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5d78baa102470b09783191f31d3a2f
https://doi.org/10.1017/s002202991900092x
https://doi.org/10.1017/s002202991900092x