Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Taiyoun Rhim"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116272- (2024)
Interest in multifunctional polymer nanoparticles for targeted delivery of anti-cancer drugs has grown significantly in recent years. In this study, tumor-targeting echogenic polymer micelles were prepared from poly(ethylene glycol) methyl ether-alky
Externí odkaz:
https://doaj.org/article/0a5ee5d0b61746b1ad4e94a2d8febf5b
Autor:
Kunho Chung, Irfan Ullah, Yujong Yi, Eunhwa Kang, Gyeongju Yun, Seoyoun Heo, Minkyung Kim, Seong-Eun Chung, Seongjun Park, Jaeyeoung Lim, Minhyung Lee, Taiyoun Rhim, Sang-Kyung Lee
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 290 (2024)
Ischemic stroke-induced neuronal cell death leads to the permanent impairment of brain function. The Fas-mediating extrinsic apoptosis pathway and the cytochrome c-mediating intrinsic apoptosis pathway are two major molecular mechanisms contributing
Externí odkaz:
https://doaj.org/article/e8231abf1c5246b7990ae1ed4c26a8e0
Autor:
Sungeun Chung, Yujong Yi, Irfan Ullah, Kunho Chung, Seongjun Park, Jaeyeoung Lim, Chaeyeon Kim, Seon-Hong Pyun, Minkyung Kim, Dokyoung Kim, Minhyung Lee, Taiyoun Rhim, Sang-Kyung Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 661 (2024)
Apoptosis plays a crucial role in neuronal injury, with substantial evidence implicating Fas-mediated cell death as a key factor in ischemic strokes. To address this, inhibition of Fas-signaling has emerged as a promising strategy in preventing neuro
Externí odkaz:
https://doaj.org/article/859089b4818e46f89e1d35c5e23ce12c
Publikováno v:
Toxics, Vol 12, Iss 1, p 7 (2023)
Poly(vinyl chloride) (PVC) is widely used to produce various consumer goods, including food packaging, toys for children, building materials, and cosmetic products. However, despite their widespread use, phthalate plasticizers have been identified as
Externí odkaz:
https://doaj.org/article/80bd74fc5cba4c6e9ca1875462abc26e
Autor:
Young Kyoung Han, Eun Ju Jeong, Yerang Seo, In Young Lee, Suim Choi, Hyewon Lee, Choonggu Kim, Taiyoun Rhim, Kuen Yong Lee
Publikováno v:
ACS Nano. 17:70-83
The demand for body fat reduction is increasing. However, conventional lipolytic approaches fail to control adipose tissue reduction and cause severe side effects in adjacent nonadipose tissues. A strategy to specifically reduce subcutaneous fat usin
Publikováno v:
BioMed Research International, Vol 2020 (2020)
BioMed Research International
BioMed Research International
Chemotherapy based on 5-fluorouracil (5-FU) is the standard approach for colon cancer treatment, and resistance to 5-FU is a significant obstacle in the clinical treatment of colon cancer. However, the mechanisms underlying 5-FU resistance in colon c
Publikováno v:
Nanoscale. 12(2)
Cell-type-specific genes involved in disease can be effective therapeutic targets; therefore, the development of a cell-type-specific gene delivery system is essential. In this study, targeted delivery of Chil3 and Chil4 siRNA to activated macrophage
Publikováno v:
Gene Therapy. 24:727-734
Asthma is a multifactorial disease that is influenced by the interaction of genetic and environmental factors. Because of its complex nature, there is no cure for asthma currently. Instead, reliever and controller medications are used to treat asthma
Publikováno v:
Journal of Drug Targeting. 25:156-162
Glioblastoma is the most malignant form of brain tumor. In this study, combination therapy with temozolomide (TMZ) and the herpes simplex virus thymidine kinase (HSVtk) gene was evaluated in glioblastoma models. The R7L10 peptide was used as a carrie
Autor:
Taiyoun Rhim, Kuen Yong Lee
Publikováno v:
Macromolecular Research. 24:577-586
Nano-sized systems have been used extensively for the delivery of various therapeutics, such as pharmaceuticals, proteins, and nucleic acids. Exosomes are small extracellular vesicles secreted from parent cells by fusion of multivesicular late endoso