Discovery of novel heteroaryl alkynes for highly potent KITD816V cells inhibition to treat gastrointestinal stromal tumors

Autor: Zhicheng Xie, Lin Li, Yihao Guo, Mi Zhang, Taiwen Chen, Yongpeng Li, Xin Li, Xi Zhu, Yu Zhang, Liguang Lou, Youhong Hu

Publikováno v: Acta Pharmaceutica Sinica B, Vol 12, Iss 10, Pp 4004-4007 (2022)

Externí odkaz: https://doaj.org/article/6dd6eae4e04d466d9bdb255d98d97132

Discovery of Potent Antiallergic Agents Based on an

Autor: Zhicheng, Xie, Caigui, Xiang, Xin, Li, Chen, Fan, Taiwen, Chen, Moting, Liu, Yanjie, Ma, Fang, Bai, Wei, Tang, Youhong, Hu

Publikováno v: Journal of medicinal chemistry. 64(18)

Effective therapeutic agents are highly desired for immune-mediated allergic diseases. Herein, we report the design, synthesis, and structure-activity relationship of an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0fcd77d4f4071b17ef9e71013a5255f1
https://pubmed.ncbi.nlm.nih.gov/34476950

Development of the Asthma Impairment and Risk Questionnaire (AIRQ): A Composite Control Measure

Autor: Kari C. Nadeau, Anthony R. Ricci, Rosalba E. Puente, Karin S. Coyne, Acklema Mohammad, Patricia H. Stewart, Peggy Rubio O’Connor, Kevin R. Murphy, Nathan James Lesch, Pulin P. Patel, Russell Settipane, Reneé Stadtler, David C. Mares, Jeffrey Rehm, James M. Eudicone, Rabinder Sidhu, Weily Soong, Christine Czajkowski, Allison Ramsey, Amanda L. Michaud, Lori A. Bowers, Xavier Soler, Theodore E. Kelbel, Andrew M. Smith, S. Shahzad Mustafa, Ewa Rakowski, Martha V. White, Raji M. Ayinla, Robert A. Wise, Bruce M. Schnapf, Maxcie M. Sikora, Brett V. Kettelhut, Sherif Al-Farra, Jason M. Bellak, Tabarak Qureshi, Vipin Jain, Adam T. Cherry, Danuel Hamlin, Jennifer Trevor, Taiwen Chen, Lindsay D. Humes, Joseph Dominic Fisher, Neal Jain, Sonia N. Bains, James E. Pearl, Florence Ida Hsu, Patricia L. Luthin, Ziad R. Mattar, Chitra R. Natalie, Edward Schuman, Kartik Shenoy, Susan Estrella-Eades, Mitchell Smith, Gary N. Gross, Ileen Gilbert, Cara Kraft, Francis J. Averill, William McCann, Bradley E. Chipps, Howard J. Lee, J. Paul Cook, Leslie A. Stefanowicz, B. Steele Rolston, Jonathan R. Romeo, R. Sharon Chinthrajah, Sami Abdul Jawad, Brian Stone, Eugene R. Bleecker, Daisy Arce, David G. Hill, John G. Southard, Justin Greiwe, Jonathan Ilowite, Christine Anderson, Joann Blessing-Moore, Jorge Manuel Mercado, Amy Palmer, James P. Krainson, Jill Hanson, Sarah Villegas, Sandra G. Adams, Ellen R. Sher, Karen L. Gregory, Thomas P. Miller, Hassan Nasir, David Pham, Neil Parikh, Bryan Krajicek, John Gedell, Gale Harding, Devi K. Jhaveri, Steven L. Wise, Salim Surani, Maeve Edel O’Connor, Alan Gaines, Franco Barsanti, Andrew S. Kim, Matthew C. Wilson, Andrew A. White, David A. Beuther, Javier Perez-Fernandez, Igor Barjaktarevic, Melvin Lee Morganroth, Matthew Hegewald, Shyamsunder Subramanian, H. Gandhi, Jodi H. Biller, G. Gilbert Head, Da-Wei Liao, Nicholas L. Hartog, Carly Hopkins, Brian D. Modena, Richard A. Wachs, Rory L. Duplantier, Edward Kerwin, Robert S. Zeiger, Laren D. Tan, Aaron K. Kobernick, Randall Brown, Susan M. Smith, Jon Eric Chancellor, Alan Fein, Peter Schochet, Geoffrey Chupp, Mario F. Perez, Ronald C. Balkissoon, Derek K. Johnson, Nabeel Farooqui, Steven G. Kelsen, Diego J. Maselli, Jessica Freyer Most, Pinkus Goldberg, Deborah Simmons

Publikováno v: The Journal of Allergy and Clinical Immunology: In Practice. 8:2263-2274.e5

Background Asthma exacerbation risk increases with worsening asthma control. Prevailing numerical control tools evaluate only current symptom impairment despite the importance of also assessing risk based on exacerbation history. An easy-to-use quest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b35c0518549ee01660539bf9966fac
https://doi.org/10.1016/j.jaip.2020.02.042

Lithology prediction of Wara and Burgan Formations using prestack geostatistical inversion: a case study in Kuwait

Autor: Sethu Madhavan, Mohamed Hafez Jaseem, Anandan Mudavakkat, Taiwen Chen, Karam Mohamed Hafez Abd Rabu

Publikováno v: SEG Technical Program Expanded Abstracts 2017.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c257a19e5804949ef82778b18b52ac2
https://doi.org/10.1190/segam2017-17672646.1

Bridging the Gap - Using AVO to Detect Changes in Fundamental Elastic Constants

Autor: Bill Goodway, David Gray, Taiwen Chen

Publikováno v: 61st EAGE Conference and Exhibition.

Two new seismic amplitude with offset (AVO) equations have been derived. These equations express the change in AVO in terms of the fundamental elastic rock properties of either Bulk Modulus or Lame's Modulus with Sheaz Modulus and Density. The AVO re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56437759af2073c95e8eae8ec6e8d858
https://doi.org/10.3997/2214-4609.201407877