Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tait Huso"'
Autor:
Lionel Chia, Bowen Wang, Jung-Hyun Kim, Li Z. Luo, Shuai Shuai, Iliana Herrera, Sophia Y. Chen, Liping Li, Lingling Xian, Tait Huso, Mohammad Heydarian, Karen Reddy, Woo Jung Sung, Shun Ishiyama, Gongbo Guo, Elizabeth Jaffee, Lei Zheng, Leslie M. Cope, Kathy Gabrielson, Laura Wood, Linda Resar
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 6 (2023)
High mobility group A1 (HMGA1) chromatin regulators are upregulated in diverse tumors where they portend adverse outcomes, although how they function in cancer remains unclear. Pancreatic ductal adenocarcinomas (PDACs) are highly lethal tumors charac
Externí odkaz:
https://doaj.org/article/309e97a7809b4c8b872864ba59ca2243
Autor:
Alyssa N. Wenzel, MD, Thomas Auld, MD, Anson Bautista, MD, Tait Huso, MD, Harpal S. Khanuja, MD
Publikováno v:
Arthroplasty Today, Vol 19, Iss , Pp 101088- (2023)
A 51-year-old woman suffered cardiac arrest requiring emergent intraosseous access that abutted the tibial component of her total knee arthroplasty. She developed a wound at the site and knee pain which was concerning for deep infection. Subsequent i
Externí odkaz:
https://doaj.org/article/9b61c534206b45e0be67cf57859233fc
Autor:
Lingling Xian, Dan Georgess, Tait Huso, Leslie Cope, Amy Belton, Yu-Ting Chang, Wenyong Kuang, Qihua Gu, Xiaoyan Zhang, Stefania Senger, Alessio Fasano, David L. Huso, Andrew J. Ewald, Linda M. S. Resar
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The function of high mobility group A1 (Hmga1) chromatin remodelling proteins in intestinal stem cells (ISC) is unknown. Here, the authors show that Hmga1 amplifies Wnt/β-catenin signalling to enhance self-renewal and inducesSox9to expand the Paneth
Externí odkaz:
https://doaj.org/article/5e3c00d6fe3d4dd9b4ee8a6610a4fe99
Autor:
Tait Huso, Karen L. Reddy, Lionel Chia, Jung-Hyun Kim, Leslie Cope, Woo Jung Sung, Shuai Shuai, Ruitao Zhang, Linda M.S. Resar
Publikováno v:
Cancer Research. 81:2414-2414
Pancreatic ductal adenocarcinomas (PDACs) are highly lethal tumors characterized by a dense desmoplastic stroma comprised of cancer associated fibroblasts (CAFs) and fibrotic scar tissue. While stromal CAFs act as a barrier to therapy and release sig
Autor:
M Koo, T N Almasri, C Inglis, Takita Felder Sumter, Linda M.S. Resar, Lionel Chia, Y-T Chang, Lingling Xian, Tait Huso, D Reid
Publikováno v:
Current Molecular Medicine. 16:353-393
Background & Objectives: Chromatin structure is the single most important feature that distinguishes a cancer cell from a normal cell histologically. Chromatin remodeling proteins regulate chromatin structure and high mobility group A (HMGA1) protein
Autor:
Michael Koo, James Turkson, David L. Huso, Tait Huso, Patrick T. Gunning, Lingling Xian, Guosheng Liu, Brent D. G. Page, Amy Belton, Li Z. Luo, Linda M.S. Resar
Publikováno v:
Leukemia & Lymphoma. 57:2681-2684
Despite dramatic improvements in treatment and survival, acute lymphoid malignancies remain the leading cause of death in children with cancer and a highly lethal malignancy in adults.[1] Acute lym...
Autor:
Karen L. Reddy, Linda M.S. Resar, Lionel Chia, Leslie Cope, Ruitao Zhang, Shuai Shuai, David L. Huso, Tait Huso, Jung Hyun Kim, Lingling Xian
Publikováno v:
Cancer Research. 80:297-297
Pancreatic ductal adenocarcinomas (PDACs) are highly lethal tumors characterized by a dense desmoplastic stroma comprised of cancer associated fibroblasts (CAFs) and fibrotic scar tissue. While stromal CAFs provide a barrier to therapy and release si
Autor:
Michael Williams, Linda M.S. Resar, Herbert H. Hill, Raymond Reeves, Amy Belton, William F. Siems, Jeong-Jin Park, Xing Zhang, David R. Gang, Lingling Xian, Tait Huso
Publikováno v:
Journal of Proteome Research. 14:1420-1431
Although significant progress has been made in the diagnosis and treatment of colorectal cancer (CRC), it remains a leading cause of cancer death worldwide. Early identification and removal of polyps that may progress to overt CRC is the cornerstone
Autor:
Leslie Cope, Linda M.S. Resar, Wenyong Kuang, Lingling Xian, David L. Huso, Andrew J. Ewald, Stefania Senger, Amy Belton, Tait Huso, Alessio Fasano, Dan Georgess, Yu Ting Chang, Xiaoyan Zhang, Qihua Gu
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
High-mobility group A1 (Hmga1) chromatin remodelling proteins are enriched in intestinal stem cells (ISCs), although their function in this setting was unknown. Prior studies showed that Hmga1 drives hyperproliferation, aberrant crypt formation and p
Autor:
Herbert H. Hill, Linda Resar, David L. Huso, Lingling Xian, Leslie Cope, Michael Williams, Raymond Reeves, David R. Gang, Tait Huso, Jeong-Jin Park, William F. Siems
Publikováno v:
Journal of proteome research. 15(12)
Because colorectal cancer (CRC) remains a leading cause of cancer mortality worldwide, more accessible screening tests are urgently needed to identify early stage lesions. We hypothesized that highly sensitive, metabolic profile analysis of stool sam