Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Taisuke Kajino"'
Autor:
Mika Iwai, Taisuke Kajino, Masahiro Nakatochi, Kiyoshi Yanagisawa, Yasuyuki Hosono, Hisanori Isomura, Yukako Shimada, Motoshi Suzuki, Ayumu Taguchi, Takashi Takahashi
Publikováno v:
Oncogene. 42:364-373
Non-coding RNAs have an integral regulatory role in numerous functions related to lung cancer development. Here, we report identification of a novel lncRNA, termed TP53-inhibiting lncRNA (TILR), which was found to function as a constitutive negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892a7e4371660a4b5cd98266502575e5
https://doi.org/10.1038/s41388-022-02546-w
https://doi.org/10.1038/s41388-022-02546-w
Autor:
Ichidai Tanaka, Gargy Parhy, Jaime Rodriguez-Canales, Veera Baladandayuthapani, Francesco C. Stingo, Toyofumi F. Chen-Yoshikawa, Rekha Jain, Seiichi Kato, Jennifer B. Dennison, Kim Anh Do, Yasushi Yatabe, Taisuke Kajino, Kohei Yokoi, Masahiro Nakatochi, Edwin R. Parra, Koji Kawaguchi, Mei Chee Tai, Clemente Aguilar-Bonavides, Ignacio I. Wistuba, Hiroyuki Katayama, Nese Unver, Muge Celiktas, Delphine Dayde, Barbara Mino, Waki Hosoda, Edwin J. Ostrin, Dilsher Dhillon, Johannes F. Fahrmann, Philip L. Lorenzi, Samir M. Hanash, Junya Fujimoto, Carmen Behrens, Yoshiko Murakami, Takayuki Fukui, Satyendra C. Tripathi, Tetsunari Hase, Yoshinori Hasegawa, Julian P. Casabar, Hong Wang, Adi F. Gazdar, Haruki Mori, Ayumu Taguchi, Luisa M. Solis
Publikováno v:
J Natl Cancer Inst
Background Approximately 20% of lung adenocarcinoma (LUAD) is negative for the lineage-specific oncogene Thyroid transcription factor 1 (TTF-1) and exhibits worse clinical outcome with a low frequency of actionable genomic alterations. To identify mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad981770cefe64c8aca4314e255a5cc6
https://doi.org/10.1093/jnci/djab183
https://doi.org/10.1093/jnci/djab183
Autor:
Takashi Murate, Atsuko Niimi, Toshiyuki Takeuchi, Takayuki Fukui, Yasuyoshi Mizutani, Tetsunari Hase, Ken Ichi Inada, Hanxiao Shi, Kazuya Shiogama, Shuta Tomida, Taisuke Kajino, Motoshi Suzuki, Toyofumi F. Chen-Yoshikawa, Takashi Takahashi, Yoshiyuki Kawamoto, Hirofumi Shibata, Takahiro Hatta, Kazuki Nagano
Publikováno v:
Cancer Science
Ceramide synthase 6 (CERS6) promotes lung cancer metastasis by stimulating cancer cell migration. To examine the underlying mechanisms, we performed luciferase analysis of the CERS6 promoter region and identified the Y‐box as a cis‐acting element
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15caf80e7a329542681ebe1a1d95c18
http://europepmc.org/articles/PMC8253294
http://europepmc.org/articles/PMC8253294
Autor:
Haruki Mori, Hisanori Isomura, Shuang Zhou, Taisuke Kajino, Yuichi Abe, Takashi Kinoshita, Seiji Natsume, Yusuke Sato, Akira Ouchi, Toru Miyake, Waki Hosoda, Koji Komori, Yasuhiro Shimizu, Masaji Tani, Ayumu Taguchi
Publikováno v:
Cancer Research. 83:3599-3599
Background: Peritoneal metastasis occurs in approximately 7% of colorectal cancer (CRC) patients and is associated with worse prognosis compared to non-peritoneal metastasis. In CRC patients with peritoneal metastasis, administration of systemic chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c576ba6ec7b2285f6f4e6442a09ef3a6
https://doi.org/10.1158/1538-7445.am2023-3599
https://doi.org/10.1158/1538-7445.am2023-3599
Autor:
Tomoya Yamaguchi, Ayumu Taguchi, Kazuo Shin-ya, Motoshi Suzuki, Takashi Takahashi, Lisa Kondo-Ida, Yukako Shimada, Behnoush Khaledian, Noritaka Kagaya, Taisuke Kajino
Publikováno v:
Cancer Science
We have previously identified receptor tyrosine kinase‐like orphan receptor 1 (ROR1) as a direct transcriptional target of TTF‐1/NKX2‐1, a lineage‐survival oncogene in lung adenocarcinoma. ROR1 sustains prosurvival signaling from multiple rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c0bebb7f8b2066c13b3f2d8bee9c1d
https://doi.org/10.1111/cas.14786
https://doi.org/10.1111/cas.14786
Autor:
Keiko Suzuki, Masahide Takahashi, Kiyoshi Yanagisawa, Masahiro Nakatochi, Ayumu Taguchi, Seiichi Kato, Teruaki Fujishita, Naoya Asai, Hisanori Isomura, Taisuke Kajino, Takashi Takahashi, Motoshi Suzuki, Tomoya Yamaguchi
Publikováno v:
Cancer Science
We previously reported that ROR1 is a crucial downstream gene for the TTF‐1/NKX2‐1 lineage‐survival oncogene in lung adenocarcinoma, while others have found altered expression of ROR1 in multiple cancer types. Accumulated evidence therefore ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e204e9f278007e6e923ef45bb50eac3a
https://pubmed.ncbi.nlm.nih.gov/33506575
https://pubmed.ncbi.nlm.nih.gov/33506575
Autor:
Zhuoran Liu, Takashi Takahashi, Yukako Shimada, Taisuke Kajino, Motoshi Suzuki, Masahiro Nakatochi, Mei Chee Tai, Sebastian Griesing
Publikováno v:
Cancer Science
Thyroid transcription factor‐1 (TTF‐1), also known as NKX2‐1, plays a role as a lineage‐survival oncogene in lung adenocarcinoma that possesses double‐edged sword characteristics. Although evidence from previous studies has steadily accumul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4f32063f8f51eb9d84b10704e6855c
https://doi.org/10.1111/cas.13271
https://doi.org/10.1111/cas.13271
Autor:
M. Iwai, Naoe Hotta, Zhuoran Liu, Motoshi Suzuki, Kiyoshi Yanagisawa, Keiko Kano, Sebastian Griesing, Taisuke Kajino, Takashi Takahashi
Publikováno v:
Oncogene. 36:3740-3748
TTF-1, also known as NKX2-1, is a transcription factor that has indispensable roles in both lung development and physiology. We and others have reported that TTF-1 frequently exhibits high expression with increased copy number in lung adenocarcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dace46e14232ab2d72634b57a569b11d
https://doi.org/10.1038/onc.2016.524
https://doi.org/10.1038/onc.2016.524
Autor:
Lisa Ida, Taisuke Kajino, Teppei Shimamura, Takashi Takahashi, Satoru Miyano, Motoshi Suzuki, Kiyoshi Yanagisawa, Shuyi Gong, Keiko Kano, Masahiro Nakatochi, Sebastian Griesing, Yukako Shimada
Publikováno v:
EMBO J
Long non-coding RNAs (lncRNAs) function in a wide range of processes by diverse mechanisms, though their roles in regulation of oncogenes and/or tumor suppressors remain rather elusive. We performed a global search for lncRNAs affecting MYC activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72efa7a0ca740776a7685b4e3ef69a6d
https://europepmc.org/articles/PMC6717891/
https://europepmc.org/articles/PMC6717891/
Autor:
Satoru Miyano, Taisuke Kajino, Teppei Shimamura, Satoshi Ito, Yusuke Matsui, Takashi Takahashi
Publikováno v:
Computational Intelligence Methods for Bioinformatics and Biostatistics ISBN: 9783030141592
CIBB
CIBB
The regulation of transcription factor activity dynamically changes across cellular conditions and disease subtypes. The identification of biological modulators contributing to context-specific gene regulation is one of the challenging tasks in syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f8d78df158c3a6e966c5498e63b757a
https://doi.org/10.1007/978-3-030-14160-8_13
https://doi.org/10.1007/978-3-030-14160-8_13