Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Taisuke Hirano"'
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Peptide-nucleic acids (PNAs) with pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone (PPT) as a universal base: their synthesis and binding affinity for oligodeoxyribonucleotides
Autor: Yoshihiro Hayakawa, Masanori Kataoka, Taisuke Hirano, Kenji Kuroda
Publikováno v: Organicbiomolecular chemistry. 7(14)
Peptide-nucleic acids (PNAs) including pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone (PPT) as a nucleobase were synthesized, and their binding affinity for the complementary oligodeoxyribonucleotides was investigated. We found that PNAs wi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e45404165216f7ae9bd4a821e454951
https://pubmed.ncbi.nlm.nih.gov/19582300
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3
Controlled release of protein drugs from newly developed amphiphilic polymer-based microparticles composed of nanoparticles
Autor: Masakazu Koiwa, Nobuo Ida, Yoichiro Koshi, Reiji Nishio, Yoshinori Kakizawa, Mio Nukiwa, Taisuke Hirano, Michizoe Junji
Publikováno v: Journal of controlled release : official journal of the Controlled Release Society. 142(1)
A novel formulation of biodegradable microparticles was developed for the sustained release of peptide and protein drugs. The microparticles were formed by the aggregation of protein nanoparticles through water-in-oil (W/O) emulsion-lyophilization an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419579ea71d4e12c5128d061a1ff1c26
https://pubmed.ncbi.nlm.nih.gov/19804802
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5
Binding affinity of a peptide nucleic acid containing pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a nucleobase for oligonucleotides
Autor: Yoshihiro Hayakawa, Masanori Kataoka, Kenji Kuroda, Taisuke Hirano
Publikováno v: Nucleic acids symposium series (2004). (51)
In order to examine the potentiality as a universal nucleobase of pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone (PPT) incorporated in a peptide-nucleic acid (PNA), we synthesized a PNA with PPT, that is H-Gly-CCT(PPT)TCC-Lys-NH2, and inves
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326d89f2f3a4393c73c9258480561538
https://pubmed.ncbi.nlm.nih.gov/18029684
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6
Pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H, 3H, 6H, 8H)-tetraone as a novel universal base
Autor: Masanori Kataoka, Yoshihiro Hayakawa, Taisuke Hirano, Kenji Kuroda
Publikováno v: Nucleic acids symposium series (2004). (49)
A derivative of pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone (PPT), which may form various keto-enol tautomers suitable for forming base pairs with all natural bases, and is thus expected to serve as a universal base, was synthesized. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52787420fb96555c90e543d173f10171
https://pubmed.ncbi.nlm.nih.gov/17150662
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7
Synthesis of a peptide nucleic acid oligomer with pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a nucleobase
Autor: Taisuke Hirano, Masanori Kataoka, Kenji Kuroda, Yoshihiro Hayakawa
Publikováno v: Nucleic Acids Symposium Series. 49:121-122
A peptide nucleic acid (PNA) oligomer containing pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone (PPT) as a nucleobase, which is expected to serve as a universal base, was synthesized.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5837c8fc2a7bd5abed4d3d82bc12d3de
https://doi.org/10.1093/nass/49.1.121
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