Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Taisuke, Takahashi"'
Autor:
Yuki Nakamura, PhD, Takeo Urakami, PhD, Kayoko Ishimaru, Nguyen Quoc Vuong Tran, PhD, Takafumi Shimizu, MS, William Sinko, PhD, Taisuke Takahashi, PhD, Sivapriya Marappan, PhD, Kishore Narayanan, PhD, Ramulu Poddutoori, PhD, Yoh Terada, PhD, Atsuhito Nakao, MD, PhD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 3, Pp 100249- (2024)
Background: The KIT receptor tyrosine kinase and its ligand, stem cell factor (SCF), control proliferation and survival of mast cells. Thus, targeting KIT signaling may show promise for the treatment of allergic diseases involving mast cells. Recentl
Externí odkaz:
https://doaj.org/article/1994ab6df89d4c908673e9912bac564f
Autor:
Hideyoshi Fuji, Eiji Kawaminami, Katsutoshi Ino, Taisuke Takahashi, Kenichiro Ishizu, Michinori Akaiwa, Hisashi Mihara, Risa Okimoto, Kenji Negoro, Hiroaki Tanaka
Publikováno v:
Chemical and Pharmaceutical Bulletin. 69:360-373
The M3 muscarinic acetylcholine receptor (mAChR) plays an essential pharmacological role in mediating a broad range of actions of acetylcholine (ACh) released throughout the periphery and central nerve system (CNS). Nevertheless, its agonistic functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28c0b3aab3d69e27ded3b916ab532e73
https://doi.org/10.1248/cpb.c20-00877
https://doi.org/10.1248/cpb.c20-00877
Autor:
Takeo Urakami, Taisuke Takahashi, Takafumi Shimizu, William Sinko, Yuki Nakamura, Kayoko Ishimaru, Vuong Tran, Ramulu Poddutoori, Kishore Narayanan, Sivapriya Marappan, Atsuhito Nakao, Yoh Terada
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:AB204
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::143ebf4fb99b1e0bb0b07fad82145ca3
https://doi.org/10.1016/j.jaci.2022.12.636
https://doi.org/10.1016/j.jaci.2022.12.636
Autor:
Atsuhito Nakao, Takeo Urakami, Yuki Nakamura, Kayoko Ishimaru, Vuong Tran, Taisuke Takahashi, Takafumi Shimizu, William Sinko, Venkateshwar Gummadi, Amit Dhudashiya, Ravikrishna Babu, Yoh Terada
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:AB205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfc3d2fb3f232d1c62bca5c4e027d074
https://doi.org/10.1016/j.jaci.2022.12.638
https://doi.org/10.1016/j.jaci.2022.12.638
Autor:
Hiroaki, Tanaka, Michinori, Akaiwa, Kenji, Negoro, Eiji, Kawaminami, Hisashi, Mihara, Hideyoshi, Fuji, Risa, Okimoto, Katsutoshi, Ino, Kenichiro, Ishizu, Taisuke, Takahashi
Publikováno v:
Chemicalpharmaceutical bulletin. 69(4)
The M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfbf09005d8e29ccec35c5c01c798cd7
https://pubmed.ncbi.nlm.nih.gov/33790081
https://pubmed.ncbi.nlm.nih.gov/33790081
Autor:
Hiroaki, Tanaka, Kenji, Negoro, Takanori, Koike, Issei, Tsukamoto, Kazuhiro, Yokoyama, Jun, Maeda, Yusuke, Inagaki, Yukinori, Shimoshige, Katsutoshi, Ino, Kenichiro, Ishizu, Taisuke, Takahashi
Publikováno v:
Bioorganicmedicinal chemistry. 28(13)
The M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89ba11792dcf6d5580dd33ef5423da03
https://pubmed.ncbi.nlm.nih.gov/32386953
https://pubmed.ncbi.nlm.nih.gov/32386953
Autor:
Bharat Lagu, Eric L. Bell, Effie Tozzo, Nirbhay Kumar Tiwari, Andrew Basinski, Arthur F. Kluge, Matthew M. Goddeeris, Ramesh S. Senaiar, Narasimha Rao Krishnamurthy, Ross Fredenburg, Sunil Kumar Panigrahi, Michael A. Patane, Mahaboobi Jaleel, Taisuke Takahashi, Peter Dwyer
Publikováno v:
ACS Medicinal Chemistry Letters. 9:935-940
The X-ray structure of the previously reported PPARδ modulator 1 bound to the ligand binding domain (LBD) revealed that the amide moiety in 1 exists in the thermodynamically disfavored cis-amide orientation. Isosteric replacement of the cis-amide wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0663921ac4e0f062d40544f2aece30db
https://doi.org/10.1021/acsmedchemlett.8b00287
https://doi.org/10.1021/acsmedchemlett.8b00287
Autor:
Ross Fredenburg, Matthew M. Goddeeris, Shekar Chellur, Ramesh S. Senaiar, Bharat Lagu, Mahaboobi Jaleel, Michael A. Patane, Nirbhay Kumar Tiwari, D. Ravi Krishna Babu, Arthur F. Kluge, Taisuke Takahashi, Effie Tozzo
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:533-536
Compound 1 regulates significantly fewer genes than the PPARδ modulator, GW501516. Both compounds are efficacious in a thermal injury model of muscle regeneration. The restricted gene profile of 1 relative to GW501516 suggests that 1 may be pharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80494cd1dc0ce8e0d6d599fa2dca230c
https://doi.org/10.1016/j.bmcl.2017.11.006
https://doi.org/10.1016/j.bmcl.2017.11.006
Autor:
Mahaboobi Jaleel, Matthew M. Goddeeris, Ramesh S. Senaiar, Peter Dwyer, Eric L. Bell, Sunil Kumar Panigrahi, Ross Fredenburg, Bharat Lagu, Narasimha Rao Krishnamurthy, Andrew Basinski, Michael A. Patane, Nirbhay Kumar Tiwari, Taisuke Takahashi, Effie Tozzo, Arthur F. Kluge
[Image: see text] The X-ray structure of the previously reported PPARδ modulator 1 bound to the ligand binding domain (LBD) revealed that the amide moiety in 1 exists in the thermodynamically disfavored cis-amide orientation. Isosteric replacement o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6579f783424d3bdf0cdce8fc284c2809
https://europepmc.org/articles/PMC6580794/
https://europepmc.org/articles/PMC6580794/
Autor:
Taisuke Takahashi, Hiroaki Tanaka, Katsutoshi Ino, Yukinori Shimoshige, Kazuhiro Yokoyama, Kenichiro Ishizu, Jun Maeda, Issei Tsukamoto, Takanori Koike, Yusuke Inagaki, Kenji Negoro
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115531
The M3 muscarinic acetylcholine receptor (mAChR) is a member of the family of mAChRs, which are associated with a variety of physiological functions including the contraction of various smooth muscle tissues, stimulation of glandular secretion, and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0a405641821c464ada1b883e8899333
https://doi.org/10.1016/j.bmc.2020.115531
https://doi.org/10.1016/j.bmc.2020.115531