Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Taisuke, Furusho"'
Autor:
Azuma Nanamatsu, Eisei Sohara, Tatemitsu Rai, Taisuke Furusho, Koichiro Susa, Takayasu Mori, Shinichi Uchida, Shintaro Mandai, Fumiaki Ando
Publikováno v:
Hypertension. 77:1953-1963
Urinary uromodulin, secreted by renal tubular cells, protects against urinary tract infections and kidney stones. In contrast, the intracellular accumulation of uromodulin is associated with hypertension and chronic kidney disease. However, the physi
Deletion of Alox15 improves kidney dysfunction and inhibits fibrosis by increased PGD2 in the kidney
Autor:
Fumiaki Ando, Tamami Fujiki, Takuya Fujimaru, Taisuke Furusho, Ayaka Usui, Tomoki Yanagi, Koichiro Susa, Makoto Arita, Hiroaki Kikuchi, Takayasu Mori, Kenichi Asano, Kouhei Yamamoto, Eisei Sohara, Naohiro Takahashi, Yoshiaki Matsuura, Tatemitsu Rai, Shinichi Uchida, Shintaro Mandai
Publikováno v:
Clinical and Experimental Nephrology. 25:445-455
Background Lipid-metabolizing enzymes and their metabolites affect inflammation and fibrosis, but their roles in chronic kidney disease (CKD) have not been completely understood. Methods To clarify their role in CKD, we measured the mRNA levels of ma
Autor:
Naohiro, Takahashi, Hiroaki, Kikuchi, Ayaka, Usui, Taisuke, Furusho, Takuya, Fujimaru, Tamami, Fujiki, Tomoki, Yanagi, Yoshiaki, Matsuura, Kenichi, Asano, Kouhei, Yamamoto, Fumiaki, Ando, Koichiro, Susa, Shintaro, Mandai, Takayasu, Mori, Tatemitsu, Rai, Shinichi, Uchida, Makoto, Arita, Eisei, Sohara
Publikováno v:
Clinical and Experimental Nephrology
Background Lipid-metabolizing enzymes and their metabolites affect inflammation and fibrosis, but their roles in chronic kidney disease (CKD) have not been completely understood. Methods To clarify their role in CKD, we measured the mRNA levels of ma
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension. 43(8)
The distal nephron of the kidney has a central role in sodium and fluid homeostasis, and disruption of this homeostasis due to mutations of with-no-lysine kinase 1 (WNK1), WNK4, Kelch-like 3 (KLHL3), or Cullin 3 (CUL3) causes pseudohypoaldosteronism
Autor:
Shintaro Mandai, Kohei Yamamoto, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Tomokazu Okado, Naohiro Takahashi, Moko Zeniya, Naohiro Nomura, Takayasu Mori, Shinichi Uchida, Yohei Arai, Takuya Fujimaru, Kiyoshi Isobe, Eisei Sohara, Taisuke Furusho, Hiroko Hashimoto, Tatemitsu Rai
Publikováno v:
Kidney international. 97(4)
The inappropriate over-activation of the with-no-lysine kinase (WNK)–STE20/SPS1–related proline/alanine-rich kinase (SPAK)–sodium chloride cotransporter (NCC) phosphorylation cascade increases sodium reabsorption in distal kidney nephrons, resu
Autor:
Naohiro Takahashi, Tomokazu Okado, Hiroaki Kikuchi, Fumiaki Ando, Yoji Andrew Minamishima, Takahiro Yamashita, Naohiro Nomura, Eisei Sohara, Takayasu Mori, Shintaro Mandai, Yasuhiro Maejima, Tatemitsu Rai, Shinichi Uchida, Kiyoshi Isobe, Yohei Arai, Taisuke Furusho, Emi Sasaki, Yuki Yoshizaki
Publikováno v:
Kidney international. 95(1)
The kidneys consume a large amount of energy to regulate volume status and blood pressure and to excrete uremic toxins. The identification of factors that cause energy mismatch in the setting of chronic kidney disease (CKD) and the development of int
Autor:
Shintaro Mandai, Taisuke Furusho, Hiroaki Kikuchi, Naohiro Nomura, Takayasu Mori, Shinichi Uchida, Yohei Arai, Emi Sasaki, Eisei Sohara, Tatemitsu Rai
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
With-no-lysine (K) (WNK) kinases, which are mutated in the inherited form of hypertension pseudohypoaldosteronism type II, are essential regulators of membrane ion transporters. Here, we report that WNK1 positively regulates skeletal muscle cell hype
Autor:
Taisuke Furusho, Naohiro Nomura, Eisei Sohara, Daiei Takahashi, Moko Zeniya, Wakana Shoda, Shinichi Uchida, Tatemitsu Rai, Shintaro Mandai, Yuanlong Wang
Publikováno v:
Bioscience Reports
The sodium chloride cotransporter (NCC) has been identified as a key molecule regulating potassium balance. The mechanisms of NCC regulation during low extracellular potassium concentrations have been studied in vitro. These studies have shown that h
Autor:
Naohiro Nomura, Wakana Shoda, Yuanlong Wang, Shintaro Mandai, Taisuke Furusho, Daiei Takahashi, Moko Zeniya, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida
Publikováno v:
Bioscience Reports; 2/28/2018, Vol. 38 Issue 1, p1-10, 10p