Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Taishu Kawada"'
Increased Yields of the Guanine Oxidative Damage Product Imidazolone Following Exposure to LED Light
Publikováno v:
Reactions, Vol 4, Iss 4, Pp 801-810 (2023)
Among the bases of DNA, guanine is the most easily oxidized. Imidazolone (Iz) is a guanine oxidative damage, and we sought to generate Iz-containing oligomers. In this paper, we describe the methods and conditions to increase the yield of Iz by emplo
Externí odkaz:
https://doaj.org/article/5421ef0b2fe341ae8271f52f9e4e579f
Autor:
Taishu Kawada, Katsuhito Kino, Kyousuke Tokorodani, Ryuto Anabuki, Masayuki Morikawa, Takanobu Kobayashi, Kazuaki Ohara, Takayuki Ohshima, Hiroshi Miyazawa
Publikováno v:
Genes and Environment, Vol 44, Iss 1, Pp 1-8 (2022)
Abstract Urea (Ua) is produced in DNA as the result of oxidative damage to thymine and guanine. It was previously reported that Klenow fragment (Kf) exo− incorporated dATP opposite Ua, and that DNA polymerase β was blocked by Ua. We report here th
Externí odkaz:
https://doaj.org/article/f70cd6ac609e4fbc91bb357755f3599f
Autor:
Taishu Kawada, Katsuhito Kino, Yoshihiko Matsuzawa, Masayuki Morikawa, Yasuko Okamoto, Takanobu Kobayashi, Yoshiyuki Tanaka
Publikováno v:
Molbank, Vol 2022, Iss 3, p M1436 (2022)
The title compound, N′1,N′4-bis(2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylidene)succinohydrazide (1), was obtained by the reaction of formylmethylflavin and succinic acid dihydrazide. The product 1 was characterized by
Externí odkaz:
https://doaj.org/article/d6d52cf689e34e098e46879a776a2dc8
Autor:
Katsuhito Kino, Takayuki Ohshima, Hajime Takeuchi, Takanobu Kobayashi, Taishu Kawada, Masayuki Morikawa, Hiroshi Miyazawa
Publikováno v:
Challenges, Vol 12, Iss 2, p 33 (2021)
The linear no-threshold (LNT) theory describes the linear relationship between a radiation dose and its effects. However, whether the linear relationship is maintained at low radiation doses has yet to be determined. Many previous studies support the
Externí odkaz:
https://doaj.org/article/68d8f8eb12b341808e592a00db9ae84a
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7645 (2020)
Among the natural bases, guanine is the most oxidizable base. The damage caused by oxidation of guanine, commonly referred to as oxidative guanine damage, results in the formation of several products, including 2,5-diamino-4H-imidazol-4-one (Iz), 2,2
Externí odkaz:
https://doaj.org/article/b1bcd4cef3544f7aa2709066db2a8573
Autor:
Taishu Kawada, Katsuhito Kino, Kyousuke Tokorodani, Ryuto Anabuki, Masayuki Morikawa, Takanobu Kobayashi, Kazuaki Ohara, Takayuki Ohshima, Hiroshi Miyazawa
Publikováno v:
Genes and environment : the official journal of the Japanese Environmental Mutagen Society. 44(1)
Abstract Urea (Ua) is produced in DNA as the result of oxidative damage to thymine and guanine. It was previously reported that Klenow fragment (Kf) exo− incorporated dATP opposite Ua, and that DNA polymerase β was blocked by Ua. We report here th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33da9e4bc4bfc95bfc8a12ce394a1396
https://pubmed.ncbi.nlm.nih.gov/35168664
https://pubmed.ncbi.nlm.nih.gov/35168664
Publikováno v:
Global Journal of Infectious Diseases and Clinical Research. :060-061
The spread of the novel coronavirus disease (COVID-19) has caused a global pandemic. Exiting agents that act on proteins including 3-chymotrypsin-like protease (3CLpro), papain-like protease (PLpro), helicase, RNA-dependent RNA polymerase (RdRp), spi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27639ff69f382b7af35c6da9f7e1dc2f
https://doi.org/10.17352/2455-5363.000038
https://doi.org/10.17352/2455-5363.000038
Autor:
Taishu Kawada, Masayuki Morikawa, Katsuhito Kino, Hiroshi Miyazawa, Takanobu Kobayashi, Masayo Suzuki
Publikováno v:
Chemical research in toxicology. 28(6)
Mutations induced by oxidative DNA damage can cause diseases such as cancer. In particular, G:C-T:A and G:C-C:G transversions are caused by oxidized guanine and have been observed in the p53 and K-ras genes. We focused on an oxidized form of guanine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795dc71d4c304253709d1f2e27ab38db
https://pubmed.ncbi.nlm.nih.gov/26010525
https://pubmed.ncbi.nlm.nih.gov/26010525
Autor:
Masayo Suzuki, Katsuhito Kino, Taishu Kawada, Takanori Oyoshi, Masayuki Morikawa, Takanobu Kobayashi, Hiroshi Miyazawa
Publikováno v:
Journal of Biochemistry; Mar2016, Vol. 159 Issue 3, p323-329, 7p
Autor:
Masayo Suzuki, Katsuhito Kino, Taishu Kawada, Masayuki Morikawa, Takanobu Kobayashi, Hiroshi Miyazawa
Publikováno v:
Chemical Research in Toxicology; Jun2015, Vol. 28 Issue 6, p1307-1316, 10p