Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Taishi YONEZAWA"'
Autor:
Xiaoxiao Liu, Naru Sato, Tomohiro Yabushita, Jingmei Li, Yuhan Jia, Moe Tamura, Shuhei Asada, Takeshi Fujino, Tsuyoshi Fukushima, Taishi Yonezawa, Yosuke Tanaka, Tomofusa Fukuyama, Akiho Tsuchiya, Shiori Shikata, Hiroyuki Iwamura, Chieko Kinouchi, Kensuke Komatsu, Satoshi Yamasaki, Tatsuhiro Shibata, Atsuo T Sasaki, Janet Schibler, Mark Wunderlich, Eric O'Brien, Benjamin Mizukawa, James C Mulloy, Yuki Sugiura, Hitoshi Takizawa, Takuma Shibata, Kensuke Miyake, Toshio Kitamura, Susumu Goyama
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 1, Pp n/a-n/a (2023)
Abstract Inosine monophosphate dehydrogenase (IMPDH) is a rate‐limiting enzyme in de novo guanine nucleotide synthesis pathway. Although IMPDH inhibitors are widely used as effective immunosuppressants, their antitumor effects have not been proven
Externí odkaz:
https://doaj.org/article/80b4174013704cb29ecfb11251a79951
Autor:
Keita Yamamoto, Susumu Goyama, Shuhei Asada, Takeshi Fujino, Taishi Yonezawa, Naru Sato, Reina Takeda, Akiho Tsuchiya, Tomofusa Fukuyama, Yosuke Tanaka, Akihiko Yokoyama, Hikaru Toya, Ayana Kon, Yasuhito Nannya, Rena Onoguchi-Mizutani, Shinichi Nakagawa, Tetsuro Hirose, Seishi Ogawa, Nobuyoshi Akimitsu, Toshio Kitamura
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109576- (2021)
Summary: Paraspeckles are membraneless organelles formed through liquid-liquid phase separation and consist of multiple proteins and RNAs, including NONO, SFPQ, and NEAT1. The role of paraspeckles and the component NONO in hematopoiesis remains unkno
Externí odkaz:
https://doaj.org/article/51f0dc93f4604f38953cd945fbc72291
Autor:
Tsuyoshi Fukushima, Yosuke Tanaka, Fiona K. Hamey, Chih-Hsiang Chang, Toshihiko Oki, Shuhei Asada, Yasutaka Hayashi, Takeshi Fujino, Taishi Yonezawa, Reina Takeda, Kimihito Cojin Kawabata, Tomofusa Fukuyama, Terumasa Umemoto, Keiyo Takubo, Hitoshi Takizawa, Susumu Goyama, Yasushi Ishihama, Hiroaki Honda, Berthold Göttgens, Toshio Kitamura
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 4144-4158.e7 (2019)
Summary: Quiescent hematopoietic stem cells (HSCs) are typically dormant, and only a few quiescent HSCs are active. The relationship between “dormant” and “active” HSCs remains unresolved. Here we generate a G0 marker (G0M) mouse line that vi
Externí odkaz:
https://doaj.org/article/c600fc8360c6414eb2954aef793c2274
Autor:
Shuhei Asada, Susumu Goyama, Daichi Inoue, Shiori Shikata, Reina Takeda, Tsuyoshi Fukushima, Taishi Yonezawa, Takeshi Fujino, Yasutaka Hayashi, Kimihito Cojin Kawabata, Tomofusa Fukuyama, Yosuke Tanaka, Akihiko Yokoyama, Satoshi Yamazaki, Hiroko Kozuka-Hata, Masaaki Oyama, Shinya Kojima, Masahito Kawazu, Hiroyuki Mano, Toshio Kitamura
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
ASXL1 gene is often mutated in myeloid malignancies. Here, the authors show that mutant ASXL1 and BAP1 are in a positive feedback loop such that BAP1 induces monoubiquitination of mutant ASXL1, which in turn enhances BAP1 activity to potentiate myelo
Externí odkaz:
https://doaj.org/article/b54c40c22a2a4a1b8cfc19f69a4b3607
Autor:
Kenta NAKASE, Shuta AKETA, Yasushi SHIN, Misato INOUE, Rinsei TEI, Masanori KISHI, Takanori FURUTA, Shizuka MIYAZA, Hiromitsu SASAKI, Yumi KO, Seisuke MIYAMAE, Yoshitomo UCHIYAMA, Hidetsugu MAEKAWA, Junichi IIDA, Taishi YONEZAWA
Publikováno v:
Surgery for Cerebral Stroke. 50:170-176
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aafbe4c0f53ebabff32a685dfbc4bc04
https://doi.org/10.2335/scs.50.170
https://doi.org/10.2335/scs.50.170
Autor:
Xiaoxiao Liu, Naru Sato, Tomohiro Yabushita, Jingmei Li, Yuhan Jia, Moe Tamura, Shuhei Asada, Takeshi Fujino, Tsuyoshi Fukushima, Taishi Yonezawa, Yosuke Tanaka, Tomofusa Fukuyama, Akiho Tsuchiya, Shiori Shikata, Hiroyuki Iwamura, Chieko Kinouchi, Kensuke Komatsu, Satoshi Yamasaki, Tatsuhiro Shibata, Atsuo T Sasaki, Janet Schibler, Mark Wunderlich, Eric O'Brien, Benjamin Mizukawa, James C Mulloy, Yuki Sugiura, Hitoshi Takizawa, Takuma Shibata, Kensuke Miyake, Toshio Kitamura, Susumu Goyama
Publikováno v:
EMBO molecular medicineReferences.
Inosine monophosphate dehydrogenase (IMPDH) is a rate-limiting enzyme in de novo guanine nucleotide synthesis pathway. Although IMPDH inhibitors are widely used as effective immunosuppressants, their antitumor effects have not been proven in the clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1794d97dd2d4857c2bef277c60e3907
https://pubmed.ncbi.nlm.nih.gov/36453131
https://pubmed.ncbi.nlm.nih.gov/36453131
Autor:
Katharina Wohlan, Lorenzo Brunetti, Joanne I. Hsu, Katie A. Matatall, Rebecca L. Murdaugh, Linda Zhang, Anna Guzman, Jack Toups, Daniel Hormaechea-Agulla, Carina Rosas, Meghan Kisiel, Ayumi Kitano, Tianyuan Hu, Yu-Jung Tseng, Bailee N. Kain, Sara Biesiadny, Jonathan Tiessen, Minhua Li, Marcus Florez, Sarah Waldvogel, Kristen Kurtz, Mira Jeong, Duy Le, Daniel E. Morales-Mantilla, Hannah Yan, Alejandra Garcia Martell, Chiraag D. Kapadia, Yung-Hsin Huang, Shannon E. Conneely, Rogelio Aguilar, Xiangguo Shi, Tianpeng Gu, Hyojeong Han, Yajian Jiang, Jason Rogers, Taishi Yonezawa, Apoorva Thatavarty, Ruoqiong Cao, Trisha K. Wathan, Nesa Mercer, Daniel Kennedy, Ayala Tovy, Jaime M. Reyes, Marek Kimmel, Yun Huang, Daisuke Nakada, Katherine Y. King, Margaret A. Goodell
Publikováno v:
Blood. 140:8590-8591
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8854d5a1012ab58db00736729d253d29
https://doi.org/10.1182/blood-2022-164858
https://doi.org/10.1182/blood-2022-164858
Autor:
Hikaru Toya, Naru Sato, Taishi Yonezawa, Yosuke Tanaka, Akihiko Yokoyama, Tetsuro Hirose, Yasuhito Nannya, Keita Yamamoto, Tomofusa Fukuyama, Rena Onoguchi-Mizutani, Takeshi Fujino, Akiho Tsuchiya, Shinichi Nakagawa, Reina Takeda, Ayana Kon, Seishi Ogawa, Shuhei Asada, Susumu Goyama, Toshio Kitamura, Nobuyoshi Akimitsu
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109576-(2021)
Summary: Paraspeckles are membraneless organelles formed through liquid-liquid phase separation and consist of multiple proteins and RNAs, including NONO, SFPQ, and NEAT1. The role of paraspeckles and the component NONO in hematopoiesis remains unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6836b89b7ddd47951277e1cd27fb863
https://pubmed.ncbi.nlm.nih.gov/34433054
https://pubmed.ncbi.nlm.nih.gov/34433054
Autor:
Hirotaka Takahashi, Toshio Kitamura, Shiori Shikata, Taishi Yonezawa, Susumu Goyama, Tatsuya Sawasaki
Publikováno v:
Biochemical and Biophysical Research Communications. 505:905-909
RUNX1 is a member of RUNX transcription factors and plays important roles in hematopoiesis. RUNX1 function is under the tight control through posttranslational modifications, including phosphorylation and ubiquitination. We previously developed a lum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1675e52f01de95172552a5601bc8a6
https://doi.org/10.1016/j.bbrc.2018.10.006
https://doi.org/10.1016/j.bbrc.2018.10.006
Autor:
Taishi Yonezawa, Keiyo Takubo, Berthold Göttgens, Yosuke Tanaka, Toshio Kitamura, Y Hayashi, Tsuyoshi Fukushima, Chih-Hsiang Chang, Shuhei Asada, Terumasa Umemoto, Tomofusa Fukuyama, Reina Takeda, Takeshi Fujino, Yasushi Ishihama, Hiroaki Honda, Hitoshi Takizawa, Toshihiko Oki, Fiona K. Hamey, Kimihito Cojin Kawabata, Susumu Goyama
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 4144-4158.e7 (2019)
Quiescent hematopoietic stem cells (HSCs) are typically dormant, and only a few quiescent HSCs are active. The relationship between “dormant” and “active” HSCs remains unresolved. Here we generated a G0 marker (G0M) mouse line that visualizes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb294f1a699209a865c00c7ce878557
https://www.repository.cam.ac.uk/handle/1810/300038
https://www.repository.cam.ac.uk/handle/1810/300038
