Výsledky vyhledávání - "Taishi Niimi"

Development of a spray-type adhesion barrier

Autor: Taishi Niimi, Miho Kai, Tetsuro Kawanishi, Ishihara Hiroyuki, Naotaka Chino

Publikováno v: Polymer Journal. 52:473-479

We developed a novel spray-type dextrin hydrogel-based adhesion barrier designed to create a site-specific barrier on a target. Our novel hydrogel is composed of Powder A, which mainly contains N-hydroxysuccinimide-modified carboxymethyl dextrin and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16ceab5529e19b9bb2037ef45d57ac7b
https://doi.org/10.1038/s41428-020-0306-0

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Synthesis and evaluation of novel phosphasugar anticancer agents

Autor: Mayumi Yamaoka, Nobuhisa Ozaki, Keita Kiyofuji, Satoki Nakamura, Junko Yamashita, Akiho Sawada, Mitsuji Yamashita, Kazuhide Asai, Mitsuo Toda, Masaki Sugiyama, Taishi Niimi, Manabu Yamada, Reiko Makita, Michio Fujie, Takuya Suyama, Kazunori Ohnishi

Publikováno v: Pure and Applied Chemistry. 84:37-48

Starting materials of phosphasugars, 1-phenyl-2-phospholene 1-oxides, were prepared from dienes and phenylphosphonous dichloride (dichlorophenylphosphine). Several substituted novel phosphasugars (3- or 4-halo-substituted)-1-phenyl-2-phospholene 1-ox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::58d5701661e00fe84110ab816dfe82fd
https://doi.org/10.1351/pac-con-11-10-09

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Preparation of Phospha Sugar Analogues and Their Evaluation as Novel Molecular Targeting Anticancer Agents

Autor: Michio Fujie, Taishi Niimi, Kenji Tsunekawa, Satoru Ito, Junko Yamashita, Nobuhisa Ozaki, Satoki Nakamura, Manabu Yamada, Kazuhide Asai, Takuya Suyama, Mitsuji Yamashita

Publikováno v: Phosphorus, Sulfur, and Silicon and the Related Elements. 186:936-944

Phospha sugars were prepared by a novel synthetic route starting from phosphorus heterocyclic compounds, 2-phospholenes. The anhydro- and deoxy-phospha sugar derivatives have been revealed to have potential anticancer activities against human leukemi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d18326030263c06022f051902820cb80
https://doi.org/10.1080/10426507.2010.530326

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Preparation and Characterization of Phospha Sugar Analogues, 2,3-Dibromo-3-methyl-1- phenylphospholane 1-Oxide Derivatives, as Novel Anticancer Agents

Autor: Junko Yamashita, Manabu Yamada, Michio Fujie, Mitsuji Yamashita, Takuya Suyama, Taishi Niimi, Satoki Nakamura, Kazuhide Asai, Kasthuraiah Maddali

Publikováno v: Phosphorus, Sulfur, and Silicon and the Related Elements. 185:2286-2291

The synthesis of new phospha sugar analogues or phosphorus heterocycles and their biological activities as novel anticancer agents are reported in this article. A 1,2-dibromo-1,2-dideoxy phospha sugar derivative, 2,3-dibromo-3-methyl-1-phenylphosphol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ad0aa908aa8dae3b1103f0eb075622b
https://doi.org/10.1080/10426501003598622

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Preparation and characterization of novel 4-bromo-3,4-dimethyl-1-phenyl-2-phospholene 1-oxide and the analogous phosphorus heterocycles or phospha sugars

Autor: Kazuhide Asai, Kasthuraiah Maddali, Satoki Nakamura, Takuya Suyama, Kazunori Ohnishi, Michio Fujie, Junko Yamashita, Manabu Yamada, Taishi Niimi, Mitsuji Yamashita, Nobuhisa Ozaki

Publikováno v: Bioorganicmedicinal chemistry letters. 20(19)

4-Bromo-3,4-dimethyl-1-phenyl-2-phospholene 1-oxide ( 3c ) was first synthesized from 3,4-dimethyl-1-phenyl-2-phospholene 1-oxide ( 2c ) by a bromo-radical substitution reaction occurred at C-4 position by N -bromosuccinimide and 2,2′-azobisisobuty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0163e0b7899e0ba61866da48a2136bb8
https://pubmed.ncbi.nlm.nih.gov/20801031

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Development and pharmacologic characterization of deoxybromophospha sugar derivatives with antileukemic activity

Autor: Isao Hirano, Mitsuji Yamashita, Junko Yamashita, Yukiko Iguchi, Takuya Suyama, Kazunori Ohnishi, Kiyoshi Shibata, Michio Fujie, Taishi Niimi, Takaaki Ono, Kazuhide Asai, Daisuke Yokota, Kasthuraiah Maddali, Satoki Nakamura

Publikováno v: Investigational new drugs. 28(4)

Here, we synthesized two phospha sugar derivatives, 2,3,4-tribromo-3-methyl-1-phenylphospholane 1-oxide (TMPP) and 2,3-dibromo-3-methyl-1-phenylphospholane 1-oxide (DMPP) by reacting 3-methyl-1-phenyl-2-phospholene 1-oxide with bromine, and investiga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6646062cfe8f66e51713932a909499da
https://pubmed.ncbi.nlm.nih.gov/19436953

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