Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Taishi Maeda"'
Autor:
Haruka Sakamoto, Yoshinari Okamoto, Hiroshi Kiwada, Tsutomu Ishihara, Tatsuhiro Ishida, Ken Ichiro Tanaka, Naoki Yamakawa, Rie Igarashi, Miho Takeda, Tohru Mizushima, Yutaka Mizushima, Naoko Takasaki, Masami Otsuka, Chisa Kobayashi, Ayumi Kimoto, Kanae Yuki, Mitsuko Takenaga, Taishi Maeda
Publikováno v:
Pharmaceutical Research. 26:2270-2279
We recently developed prostaglandin E(1) (PGE(1))-encapsulated nanoparticles, prepared with a poly(lactide) homopolymer (PLA, Mw = 17,500) and monomethoxy poly(ethyleneglycol)-PLA block copolymer (PEG-PLA) (NP-L20). In this study, we tested whether t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf30aa6308a4d87ea8dd6f292fe688dc
https://doi.org/10.1007/s11095-009-9943-x
https://doi.org/10.1007/s11095-009-9943-x
Autor:
Yasuo Nagaoka, Yuki Kawai, Shinichi Uesato, Koji Shimoke, Hiroshi Kuwajima, D. Nakashima, Tadao Oikawa, Taishi Maeda, Toshihiko Ikeuchi
Publikováno v:
European Journal of Medicinal Chemistry. 41:697-708
New series histone deacetylase inhibitors comprising a hydroxamic acid or 2-aminobenzamide group as a zinc-chelating function were synthesized and evaluated for antiproliferative activities against a panel of human cancer cells. The 2-aminobenzamide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733b5f27271a4a04758957e34fc6b7f0
https://doi.org/10.1016/j.ejmech.2006.02.002
https://doi.org/10.1016/j.ejmech.2006.02.002
Autor:
Tatsuhiro Ishida, Hiroshi Kiwada, Masao Shigyo, Haruka Sakamoto, Taishi Maeda, Tsutomu Ishihara, Yutaka Mizushima, Naoko Takasaki, Tohru Mizushima
Publikováno v:
Biomacromolecules. 11(10)
The accelerated blood clearance (ABC) phenomenon is induced upon repeated injections of poly(ethylene glycol) (PEG)-coated colloidal carriers. It is essential to suppress this phenomenon in a clinical setting because the pharmacokinetics must be repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fafe6e29cd4627099c3d5482de0de9
https://pubmed.ncbi.nlm.nih.gov/20795699
https://pubmed.ncbi.nlm.nih.gov/20795699
Autor:
Fumihiro Nishimura, Taishi Maeda, Ken Ichiro Tanaka, Masami Otsuka, Naoki Yamakawa, Tsutomu Ishihara, Haruka Sakamoto, Yutaka Mizushima, Takeshi Yamashita, Kanae Yuki, Naoko Takasaki, Rie Igarashi, Tohru Mizushima, Mitsuko Takenaga, Miho Takeda, Megumu Higaki, Yoshinari Okamoto, Hisao Ogawa
Publikováno v:
Pharmaceutical research. 26(7)
Prostaglandin E(1) (PGE(1)) is an effective treatment for peripheral vascular diseases. The encapsulation of PGE(1) in nanoparticles for its sustained-release would improve its therapeutic effect and quality of life (QOL) of patients.In order to enca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e299ca42c3356af1667baa75f258eb5e
https://pubmed.ncbi.nlm.nih.gov/19415470
https://pubmed.ncbi.nlm.nih.gov/19415470
Autor:
Chikako Yasuda, Nobumasa Takagaki, Toshiyuki Sakai, Shingo Yogosawa, Taishi Maeda, Yuki Kawai, Yoshihiro Sowa, Yasuo Nagaoka, Shinichi Uesato
Publikováno v:
Biologicalpharmaceutical bulletin. 28(5)
Two compounds were synthesized which have a structural component other than those of our new series histone deacetylase (HDAC) inhibitors to determine the structure-activity relationship. It was also examined whether the inhibitory effects on cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6459c1e2ff2b13d438ae6f9c690487e
https://pubmed.ncbi.nlm.nih.gov/15863892
https://pubmed.ncbi.nlm.nih.gov/15863892
Autor:
Taishi Maeda, Yasuo Nagaoka, Mineko Kurotaki, Chieko Seno, Sakiko Maruyama, Hiroshi Kuwajima, Shinichi Uesato
Publikováno v:
Bioorganicmedicinal chemistry. 12(16)
The screening tests of N-hydroxybenzamides for their HDAC-inhibitory activities led to the discovery of the promising compounds with a 2-naphthylcarbonyl group and with a 1,4-biphenylcarbonyl group. These compounds were further modified to optimize t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b82a7070b137d2728382ffc516bcfa4
https://pubmed.ncbi.nlm.nih.gov/15265487
https://pubmed.ncbi.nlm.nih.gov/15265487
Autor:
Taishi Maeda, Takao Yamori, Yasuo Nagaoka, Manabu Kitagawa, Shinichi Uesato, Hiroshi Kuwajima
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(10)
Utilizing tranexamic acid as a starting material, a series of N-hydroxycarboxamides were synthesized in order to seek new histone deacetylase (HDAC) inhibitors. Further structure optimization involving the replacement of the 1,4-cyclohexylene group w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a22d3af7c019a83b22ed485b97547d5
https://pubmed.ncbi.nlm.nih.gov/11992774
https://pubmed.ncbi.nlm.nih.gov/11992774
Autor:
Tsutomu Ishihara, Taishi Maeda, Haruka Sakamoto, Naoko Takasaki, Masao Shigyo, Tatsuhiro Ishida, Hiroshi Kiwada, Yutaka Mizushima, Tohru Mizushima
Publikováno v:
Biomacromolecules; Oct2010, Vol. 11 Issue 10, p2700-2706, 7p
Autor:
Miho Takeda, Haruka Sakamoto, Ayumi Kimoto, Chisa Kobayashi, Naoko Takasaki, Kanae Yuki, Ken-ichiro Tanaka, Mitsuko Takenaga, Rie Igarashi, Taishi Maeda, Naoki Yamakawa, Yoshinari Okamoto, Masami Otsuka, Tatsuhiro Ishida, Hiroshi Kiwada, Yutaka Mizushima, Tohru Mizushima
Publikováno v:
Pharmaceutical Research; Oct2009, Vol. 26 Issue 10, p2270-2279, 10p