Zobrazeno 1 - 10
of 237
pro vyhledávání: '"Taisei Mushiroda"'
Autor:
Jody Phelan, Paula Josefina Gomez-Gonzalez, Nuria Andreu, Yosuke Omae, Licht Toyo-Oka, Hideki Yanai, Reiko Miyahara, Supalert Nedsuwan, Paola Florez de Sessions, Susana Campino, Neneh Sallah, Julian Parkhill, Nat Smittipat, Prasit Palittapongarnpim, Taisei Mushiroda, Michiaki Kubo, Katsushi Tokunaga, Surakameth Mahasirimongkol, Martin L. Hibberd, Taane G. Clark
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-7 (2023)
Few genetic loci have been associated with tuberculosis infection, possibly because of the influence of genetic variation in the pathogen. Here, the authors integrate human and Mycobacterium tuberculosis genetics to find genome-genome interactions as
Externí odkaz:
https://doaj.org/article/2b522c62dfb541f2b481485cd6e24b3a
Autor:
Ahmed El‐Boraie, Julie‐Anne Tanner, Andy Z.X. Zhu, Katrina G. Claw, Bhagwat Prasad, Erin G. Schuetz, Kenneth E. Thummel, Koya Fukunaga, Taisei Mushiroda, Michiaki Kubo, Neal L. Benowitz, Caryn Lerman, Rachel F. Tyndale
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 1, Pp 204-220 (2022)
Abstract CYP2A6 activity, phenotyped by the nicotine metabolite ratio (NMR), is a predictor of several smoking behaviors, including cessation and smoking‐related disease risk. The heritability of the NMR is 60–80%, yet weighted genetic risk score
Externí odkaz:
https://doaj.org/article/227fec3dc8d24dc2934491cf383a5b28
Autor:
kohei Ninomiya, Takeo Saito, Tomo Okochi, Satoru Taniguchi, Ayu Shimasaki, Rei Aoki, Takeo Hata, Taisei Mushiroda, Tetsufumi Kanazawa, Masashi Ikeda, Nakao Iwata
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Pharmacogenetics/pharmacogenomics have enabled the detection of risk of human leukocyte antigen (HLA) variants for clozapine-induced agranulocytosis/granulocytopenia (CIAG). To apply this evidence to the clinical setting, we compared the cos
Externí odkaz:
https://doaj.org/article/a65e8c4460b843719e3bbad2bb573c4f
Autor:
Chakkaphan Runcharoen, Koya Fukunaga, Insee Sensorn, Nareenart Iemwimangsa, Sommon Klumsathian, Hang Tong, Nam Sy Vo, Ly Le, Tin Maung Hlaing, Myo Thant, Shamsul Mohd Zain, Zahurin Mohamed, Yuh-Fen Pung, Francis Capule, Jose Nevado, Catherine Lynn Silao, Zeina N. Al-Mahayri, Bassam R. Ali, Rika Yuliwulandari, Kinasih Prayuni, Hilyatuz Zahroh, Dzul Azri Mohamed Noor, Phonepadith Xangsayarath, Dalouny Xayavong, Sengchanh Kounnavong, Somphou Sayasone, Zoe Kordou, Ioannis Liopetas, Athina Tsikrika, Evangelia-Eirini Tsermpini, Maria Koromina, Christina Mitropoulou, George P. Patrinos, Aumpika Kesornsit, Angkana Charoenyingwattana, Sukanya Wattanapokayakit, Surakameth Mahasirimongkol, Taisei Mushiroda, Wasun Chantratita
Publikováno v:
Human Genome Variation, Vol 8, Iss 1, Pp 1-6 (2021)
Abstract Pharmacogenomics can enhance the outcome of treatment by adopting pharmacogenomic testing to maximize drug efficacy and lower the risk of serious adverse events. Next-generation sequencing (NGS) is a cost-effective technology for genotyping
Externí odkaz:
https://doaj.org/article/d9ba2428e119486e956cf700ff929c5d
Autor:
Keiko Hikino, M.D., Ph.D, Masaru Koido, Ph.D., Kohei Tomizuka, B.S., Xiaoxi Liu, Ph.D., Yukihide Momozawa, D.V.M., Ph.D., Takayuki Morisaki, M.D., Ph.D., Yoshinori Murakami, M.D., Ph.D., The Biobank Japan Project, Taisei Mushiroda, Ph.D., Chikashi Terao, M.D., Ph.D.
Publikováno v:
EBioMedicine, Vol 70, Iss , Pp 103532- (2021)
Background: The underlying pathology of inguinal hernia is still not fully known; thus, further investigations of genetic backgrounds is needed. Here, we aimed to identify genetic factors attributing to inguinal hernias and explore the polygenic arch
Externí odkaz:
https://doaj.org/article/f5623259c36d489bb1e3e331798a39bd
Autor:
Xiao-Yu Zuo, Qi-Sheng Feng, Jian Sun, Pan-Pan Wei, Yoon-Ming Chin, Yun-Miao Guo, Yun-Fei Xia, Bo Li, Xiao-Jun Xia, Wei-Hua Jia, Jian-Jun Liu, Alan Soo-Beng Khoo, Taisei Mushiroda, Ching-Ching Ng, Wen-Hui Su, Yi-Xin Zeng, Jin-Xin Bei
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-11 (2019)
Abstract Background The male predominance in the incidence of nasopharyngeal carcinoma (NPC) suggests the contribution of the X chromosome to the susceptibility of NPC. However, no X-linked susceptibility loci have been examined by genome-wide associ
Externí odkaz:
https://doaj.org/article/38e8451dc36b44588032740922b7d6f0
Autor:
Noppadol Chanhom, Sukanya Wattanapokayakit, Nusara Satproedprai, Supharat Suvichapanich, Surakameth Mahasirimongkol, Usa Chaikledkaew, Wanvisa Udomsinprasert, Taisei Mushiroda, Jiraphun Jittikoon
Publikováno v:
Heliyon, Vol 7, Iss 4, Pp e06852- (2021)
Antituberculosis drug-induced liver injury (ATDILI) is the common adverse reaction of antituberculosis drugs. Glutathione S-transferases (GSTs), which are phase II metabolizing enzymes for detoxification, are recognized as potential mediators of hepa
Externí odkaz:
https://doaj.org/article/8f4f4884bd864234a2ec5801481db618
Autor:
Koya Fukunaga, Ken Kato, Takuji Okusaka, Takeo Saito, Masashi Ikeda, Teruhiko Yoshida, Hitoshi Zembutsu, Nakao Iwata, Taisei Mushiroda
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Variability in the enzymatic activity of N-acetyltransferase 2 (NAT2) is an important contributor to interindividual differences in drug responses. However, there is little information on functional differences in N-acetylation activities according t
Externí odkaz:
https://doaj.org/article/b1cd9917e30e40b192f8a82352d4445a
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/aefca20188e741aba8092817308f3087
Autor:
Daniel Shepshelovich, Amanda R. Townsend, Osvaldo Espin‐Garcia, Lidija Latifovic, Chris J. O’Callaghan, Derek J. Jonker, Dongsheng Tu, Eric Chen, Eric Morgen, Timothy J. Price, Jeremy Shapiro, Lillian L. Siu, Michiaki Kubo, Alexander Dobrovic, Mark J. Ratain, Wei Xu, Taisei Mushiroda, Geoffrey Liu
Publikováno v:
Cancer Medicine, Vol 7, Iss 11, Pp 5478-5487 (2018)
Abstract Background Two germ line Fc‐γ receptor (FCGR) polymorphisms, rs1801274 [FCGR2A; His(H)131Arg(R)] and rs396991 [FCGR3A; Phe(F)158Val(V)], produce altered proteins through amino acid substitutions. We previously reported that the FCGR2A H/H
Externí odkaz:
https://doaj.org/article/628a67c545864055ae4f182dd106b2be