Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Taisei Kinoshita"'
Autor:
Wei Li, Mark D Claypool, Annabelle M Friera, John McLaughlin, Kristen A Baltgalvis, Ira J Smith, Taisei Kinoshita, Kathy White, Wayne Lang, Guillermo Godinez, Donald G Payan, Todd M Kinsella
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94032 (2014)
Numerous human diseases can lead to atrophy of skeletal muscle, and loss of this tissue has been correlated with increased mortality and morbidity rates. Clinically addressing muscle atrophy remains an unmet medical need, and the development of precl
Externí odkaz:
https://doaj.org/article/408c765604924646b1fef41e484a25ef
Autor:
Yonchu Jenkins, Tian-Qiang Sun, Vadim Markovtsov, Marc Foretz, Wei Li, Henry Nguyen, Yingwu Li, Alison Pan, Gerald Uy, Lisa Gross, Kristen Baltgalvis, Stephanie L Yung, Tarikere Gururaja, Taisei Kinoshita, Alexander Owyang, Ira J Smith, Kelly McCaughey, Kathy White, Guillermo Godinez, Raniel Alcantara, Carmen Choy, Hong Ren, Rachel Basile, David J Sweeny, Xiang Xu, Sarkiz D Issakani, David C Carroll, Dane A Goff, Simon J Shaw, Rajinder Singh, Laszlo G Boros, Marc-André Laplante, Bruno Marcotte, Rita Kohen, Benoit Viollet, André Marette, Donald G Payan, Todd M Kinsella, Yasumichi Hitoshi
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81870 (2013)
Modulation of mitochondrial function through inhibiting respiratory complex I activates a key sensor of cellular energy status, the 5'-AMP-activated protein kinase (AMPK). Activation of AMPK results in the mobilization of nutrient uptake and cataboli
Externí odkaz:
https://doaj.org/article/9f3bbe0f39b0498d932c53dbf27c0985
Autor:
Jinlan Jiang, Nobuhiko Kojima, Taisei Kinoshita, Atsushi Miyajima, Weiqun Yan, Yasuyuki Sakai
Publikováno v:
Cell Transplantation, Vol 11 (2002)
To investigate the feasibility of fetal liver cells for liver tissue engineering, the supporting function of poly-l-lactic acid (PLLA) for fetal liver cells and the effects of oncostatin M (OSM) on hepatic differentiation were studied. After preparin
Externí odkaz:
https://doaj.org/article/dd0aa83984814ceca8f78c35d2b2335d
Autor:
Ann Rowley, Brian S. Brown, Mary Stofega, Hana Hoh, Rebecca Mathew, Violeta Marin, Rong-Xian Ding, Ryan A. McClure, Fabiola M. Bittencourt, Jun Chen, Tarikere Gururaja, Taisei Kinoshita, Xueqing Wang, Alexey Rivkin, Kevin R. Woller
Publikováno v:
ACS Chemical Biology. 17:1315-1320
Interleukin-1 receptor-associated kinase 3 (IRAK3) is a pseudokinase mediator in the human inflammatory pathway, and ablation of its function is associated with enhanced antitumor immunity. Traditionally, pseudokinases have eluded "druggability" and
Supplementary Figure S3. Response of cell signaling pathways to treatment with ibrutinib in multiple cell lines. Cells were treated for 1 hour with ibrutinib. 50,000 cells were loaded in each lane.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9ec84c461ecc62b2d44b50b3dac791
https://doi.org/10.1158/1535-7163.22508073.v1
https://doi.org/10.1158/1535-7163.22508073.v1
Supplementary Figure S2. Response of BT-474 (A) and SK-BR-3 (B) cells to treatment with different ErbB kinase inhibitors. The cells were treated with inhibitors continuously for 72 hours, and alamarBlue® assay was used to quantify cell growth.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032b59d63d16ad874db1b4b2674bcdb0
https://doi.org/10.1158/1535-7163.22508076.v1
https://doi.org/10.1158/1535-7163.22508076.v1
Supplementary Tables 1 and 2; Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::accc43c0e25045a194223343dc03f1fd
https://doi.org/10.1158/1535-7163.22508064.v1
https://doi.org/10.1158/1535-7163.22508064.v1
Supplementary Figure S5. Ibrutinib irreversibly inhibited SK-BR-3 cells, and bound covalently to EGFR and HER4 in rapid dilution assays. (A) SK-BR-3 cells were treated with ibrutinib at 0.1 and 0.5 µM for varied times before washing twice with fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eb4ceab206717ec04678c4a164b75dd
https://doi.org/10.1158/1535-7163.22508067.v1
https://doi.org/10.1158/1535-7163.22508067.v1
Supplementary Figure S4. Ibrutinib inhibited the growth of BT-474 xenograft tumors and related signaling pathways in the tumor samples. (A) Inhibition of BT-474 xenograft growth in NOD-SCID mice by ibrutinib administered at once -daily doses of 3 mg/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b54e5ed297905f65db178c4c5e9f917
https://doi.org/10.1158/1535-7163.22508070.v1
https://doi.org/10.1158/1535-7163.22508070.v1
Supplementary Figure S1. Response of MDA-MB-361 cells to multiple inhibitors. MD-MB-361 cells were plated in 96-well plates overnight before treatment with inhibitors for 72 hours. CellTiter-Glo® was used for quantifying cell growth. The assay was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5076069814bfcbd7bf81bc5d9e53c85d
https://doi.org/10.1158/1535-7163.22508079
https://doi.org/10.1158/1535-7163.22508079